Objective:To explore the influence of background data in multinutrient treatment for neonate with infection pneumonia. To study the relative risk factors in VA nutritional state. Methods:the orally vitamin A and vitamin E,zinc, selenite daily in 111 neonates in the randomized,double-blind, placebo-controlled,clinical Trial for 7 days treatment. We investigated and analyze the relevant biochemical,immune evidence, clinic data and background data, with multivariate stepwise regression analysis. Results:Mother’s age, parity,gestation age and birth weight play positive influence to clinical restoring. Neonate’s age and birth weight play a positive role to serum IgM in early stage of pneumonia,but mother’ s age is negativity. Neonate’s age is positivity in enhancing serum VA,and is negativity in advancing serum IgM. Mother’s age play a negative role to heighten serum RBP. Conclusion:Mother’s age,parity,gestation age and neonate’s age is important factors to influence the clinical treatment effect. Great age and many parity mother’s neonate,earlier period and large for date infant are more possible to VAD during sick period,and are more slow to recover. So they need the nutritional intervention all the better.

0.05).There were statistical significant differences in the cellular immunity between the immunization and no-immunization group( P

The ultrastructure of magnetotactic bacteria strain WD\|1 was reported.A thin sectioned profile of it clearly showed its cell wall,cell membrane,poly\|?\|hydroxybutyrates and magnetosomes.Meanwhile,the method of batch culture of strain WD\|1 was also reported,135mg/L dry cells could be gotten with this method.The energy profiles of X\|ray collected after electron excitation in SEM indicated that both dry cells and magnetosomes contained such mineral elements as P,S,Ca,Si,Al and Fe with different content.The iron content of its cells and magnetosomes was 3 07% and 84 57% respectively.

Objective To investigate the relationship between the doses of epidural morphine administered for postoperative analgesia and postoperative urinary retention (POUR). Methods Sixty ASA Ⅰ patients aged < 20-56 yr undergoing atthroscopic knee operation under epidural anesthesia were randomly divided into 3 groups ( n = 20 each) : group Ⅰ and Ⅱ received epidural morphine 1 and 3 mg in 5 ml of normal saline (NS) respectively at the end of operation (group M1, M2 ); group Ⅲ received NS 5 ml instead of morphine (group C). Urinary retention was defined as the patient could not void, when bladder volume was ≥ 600 ml measured using ultrasound. Bladder urine volume was measured before anesthesia and at 4, 6, 8, 10 and 12 h after operation. The occurrence of urinary retention, the first postoperative voiding time, VAS scores and the incidences of vomiting and pruritus were recorded. Results The 3 groups were comparable with respect to age, M/F sex ratio, preoperative bladder urine volume, the amount of local anesthetic used during operation and duration. The incidences of urinary retention, vomiting and pruritus were 65%, 60% and 90% respectively in group M2 and significantly higher than those in the other 2 groups. The first postoperative voiding time was significantly longer in group M2 than in the other 2 groups. VAS scores were significantly lower in group M1 and M2 than in group C. There was no significant difference in VAS scores between group M1 and M2. Conclusion Epidural morphine increases the incidence of POUR in a dose-dependent manner, and 1 mg is the recommended dose.

There is a significance of pregnancy thyroid hormone reference ranges establishment,because the consequences of thyroid dysfunction during pregnancy are terrible.This review will focus on meaning of pregnancy thyroid hormone reference range,importance of TPO antibody testing and current advances of methodology.

Objective To study the effect of Xuebijing, a Chinese traditional medicine injection, on the THP-1 cells challenged by endotoxin, and to explore whether it induces endotoxin tolerance. Methods The THP-1 cells were pretreated with Xuebijing in different concentrations (10, 25, 50 mg/mL) and times (4, 12, 24 hours), and then challenged by endotoxin. The level of TNF-α in culture supernatant was detected by ELISA assay, and the expression of TLR4 and IRAK-M mRNA were detected by Real time-PCR technique. Results There was no significant difference in TNF-α level among all the groups (pretreated with different concentrations of Xuebijing for different time) (P>0.05). Only in 50 mg/mL Xuebijing group, TLR4 mRNA was 1.547-fold increase in 24 h than in 4 h group (P<0.05). Only when pretreated for 24 h, IRAK-M mRNA was 1.349-fold increase in 50 mg/mL Xuebijing group than in control group (P<0.05). However,there was no significant difference among other groups (P>0.05). Conclusions Xuebijing can not block the release of TNF-α from the THP-1 cells challenged by endotoxin;and it does not induce endotoxin tolerance. When pretreated with high concentration of Xuebijing for long time, the expression of both TLR4 and IRAK-M mRNA is up-regulated, but its significance is not yet clear.

Clinically,peripheral nerve injury is common,treatment is still a clinical problem.Because of the peripheral nerve's particular dissection and the function,repair of its damage is a complex process,meticulous microsurgical technique can be used to restore nerve continuity,but the restoration of nerve function is still not satisfactory.Recently,the domestic and foreign scholars has made effort and achieved some success,particularly,the allograft nerve transplant has applied in clinical.

ObjectiveTo study the distribution and expression of NMDA receptor subunit 2A in the spinal cord of morphine tolerant rats. MethodsTwelve Sprague-Dawley rats were randomly divided into two groups with 6 rats each: control group (C) were intrathecally administrated 0.9% NaCl 10μl and morphine group(M) received 10μg morphine (i.t.). Drugs were administrated twice daily for 7 consecutive days. Tail flick latency (TFL) in the hot water immersion test was used to evaluate changes of thermal hyperalgesia latency of each group before and 30min after administration every morning. Rats were killed the day after last administration and L4～5 segment of the spinal cord was removed for determination the expression of NR2A by immunofluorescence method. ResultsTFL of group M was decreased gradually after chronic administration of morphine intrathecally. There was no significant difference between group M[(3.25±0.93)s] and group C[(2.66±0.27)s] on the 7th day (P＞0.05). A morphine tolerant model was established successfully. NR2A was distributed throughout the rat spinal cord. The expression of NR2A in group M(OD:9617±1233) was increased compared with group C(OD:2.66±0.93) (t=3.133,P＜0.05).ConclusionThe expression of NR2A was upregulated after repeated administration of morphine intrathecally in the superficial dorsal horn of spinal cord of morphine tolerant rats,which may be part of the mechanisms of morphine tolerance.

Tendons are dense connective tissues that mediate the attachment of the muscle system to the skeletal system. While the methods for clinical tendon repair remain less satisfactory, tissue engineering may pro- vide promising future. Therefore, understanding the natural tendon development process is important for tendon en- gineering. Scleraxis and Tenomodulin are relatively specific molecule makers for tendon and ligment and play im- portant roles in the tendon development. This article gives review of the molecular structure, the expression regula- tion, and the roles of Scleraxis and Tenomodulin in tendon development, in order to better understand the process of tendon development.

Objective To investigate the effect of electroacupuncture plus early rehabilitation training on the function recovery after surgery for cervical spinal cord injury. Methods Sixty patients with cervical spinal cord injury undergone anterior cervical decompression and internal fixation were randomized into a treatment group and a control group, 30 cases in each group. The treatment group was intervened by electroacupuncture plus rehabilitation training, while the control group was by rehabilitation training alone. The Frankel’s grading (FG), Barthel Index (BI), and Functional Independence Measure (FIM) were adopted for evaluation before and after intervention. Results The FG was not significantly changed after intervention in both groups (P>0.05). After intervention, there was no significant difference in comparing FG between the two groups (P>0.05). The BI and FIM scores were significantly changed after intervention in both groups (P＜0.01). There were significant differences in comparing BI and FIM scores between the two groups (P＜0.05). Conclusion Electroacupuncture plus early rehabilitation training can promote the function recovery after surgery for cervical spinal cord injury, and improve the quality of life.