1.Analysis of related factors of incision infection in abdominal surgical operation
Chinese Journal of Primary Medicine and Pharmacy 2017;24(5):751-754
Objective To explore the abdomen surgical incision infection risk factors,and to put forward prevention countermeasures.Methods 1 854 patients with abdominal surgery were selected as subjects.According to whether had surgical incision infection,they were divided into the infection group(76 cases)and the non -infection group(1 778 cases).Single factor analysis and Pearson correlation analysis were used to summarize abdominal surgical incision infection risk factors.Results Single factor analysis results showed that age,BMI,category of incision,operation timing,operation time,diabetes mellitus,drainage tube placement,summer were risk factors for abdominal surgery incision infection (t or χ2 =8.925,5.840,5.376,5.445,5.846,19.674,5.846,19.674,all P <0.05).Pearson correlation analysis showed that age,BMI,category of incision,operation timing,operation time,diabetes mellitus, drainage tube placement and summer surgery were risk factors for abdominal surgery incision infection (r =0.746, 0.689,0.746,0.689,0.691,0.548,0.760,0.548,all P <0.05).Conclusion Abdominal surgery incision infection is associated with many factors.It is necessary for all kinds of risk factors for targeted intervention to reduce incision infection rate.
2.Observation of the effect of cervical cerclage in the treatment of cervical incompetence
Chinese Journal of Primary Medicine and Pharmacy 2014;(z1):19-20
Objective To explore the clinical results of cervical cerclage in the treatment of cervical incom -petence.Methods Selected 63 cases of cervical incompetence of pregnant women ,according to the patient′s treat-ment voluntarily that they were divided into the observation group (cervical cerclage +conservative therapy)40 cases and the control group (conservative therapy)23 cases,indicators of pregnancy outcomes were compared between the two groups .Results There were 3 cases the late abortions ,8 cases premature deliveries ,29 cases full-term pregnan-cies in the observation group ,there were 9 cases the late abortions ,9 cases premature deliveries ,5 cases full -term pregnancies in the control group,using test,there were the differences of the statistical significants between them (χ2 =16.623,P<0.01);In the observation group,there were 0 case the late abortions,6 cases premature deliveries, 20 cases full-term pregnancies at 10~16 gestational weeks among 20 cases,there were 9 cases the late abortions,9 cases premature deliveries ,5 cases full-term pregnancies at 17~25 gestational weeks among the other 20 cases,using test,there were the differences of the statistical significants between the two time stages (χ2 =10.882,P<0.05). Conclusion For pregnant women with cervical incompetence ,cervical cerclage was made early in the pregnancy ,can extend effectively the gestational times ,improve the fetal survival .
6.Gender-specific issues in the management of patients with acute coronary syndrome.
Chinese Medical Journal 2008;121(23):2371-2373
Acute Coronary Syndrome
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diagnosis
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therapy
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Female
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Humans
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Male
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Risk Factors
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Sex Factors
9.Effect of hydroxychloroquine on the expression of suppressors of cytokine signaling in MRL/lpr mice kidney
Chinese Journal of Rheumatology 2014;18(11):773-776
Objective To study the effect of hydroxychloroquine (HCQ) on the suppressors of cytokine signaling (SOCS) in the kidney of MRL/lpr mice and evaluate the protection of HCQ on lupus nephritis.Methods Twenty-six rats were randomly divided into 3 groups:the control group which was consisted of 6 mice; the MRL/lpr group which was consisted of 10 mice; and the HCQ group which was consisted of 10.24-hour urinary protein level and anti dsDNA levels were tested.The expressions of SOCS-1 and SOCS-3 protein were determined by western blot.Analysis of variance was used to determine statistically significant differences between the two groups.A P value less than 0.05 was considered to be statistically significant.Results Compared with the control group,the levels of 24-hour urinary protein [(2 356.6±509.3) mg vs (440.3±90.1)mg] and anti ds-DNA (128.7±32.3 vs 14.9±1.4) were significantly increased in the MRL/lpr group,the expression levels of SOCS-1 and SOCS-3 protein were increased.After treated with HCQ,the levels of 24-hour urinary protein [(70.8±11.1) mg vs (2 356.6±509.3) mg] and anti-dsDNA (111.8±330.1 vs 128.7±32.3)were significantly decreased,the expression level of SOCS-1 and SOCS-3 protein decreased significantly (P＜ 0.05).Conclusion HCQ can inhibit SOCS expression in the kidney of lupus mice,reduce proteinuria and delay progression of immune disorders and lupus nephritis.
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