To study the clinical and pathological features of hepatocellular adenomas.History and comprehensive imaging features in 6 patients with confirmed hepatocellular adenomas were reviewed retrospectively and correlated with pathological findings.The results showed that all six patients had solitary adenomas. Of the 6 patients, 4 were men and 2 were women. The diameter of tumors ranged from 4 to 11 centimeters, with an average of 8.5 centimeters. All the adenomas were hypervascular, and were nearly isoattenuating to normal liver on nonenhanced, portal vein period and delayed images except for areas of necrosis, hemorrhage, or focal fatty degeneration. Six lesions showed heterogeneously high signal intensity on T1 weighted images of MRI. All tumors were resected completely, and there were no serious complications and death. It suggested that these tumors may have some common features on CT and MRI images that should allow us to improve our diagnostic ability, if we could contrast imaging features with pathological characters. The surgical operation is effective.

Objective: To establish a highly effective transformation method of Cryptococcus neoformans. Methods: Special reagents was used to make C. neoformans take in external DNA under given condition. This chemical transformation result was compared with that of electrotransformation. The feasibility of this chemical transformation was tested by plasmid stability test. Results: The efficiency of this chemical transformation was more than 103 transformants/?g plasmid DNA, far more than that of the traditional electrotransformation. Conclusion: An appropriate transformation method is established for C. neoformans transformation, which has high transformation efficiency.

Objective To evaluate the CT and pathological features of head and neck pilomatricoma.Methods We retrospectively analyzed the CT findings of 13 patients with head and neck pilomatricoma which were pathologically confirmed.Of them 7 patients received plain CT,2 patients received contrast-enhancement,and 4 patients received plain CT plus contrast-enhancement.Results All the patients presented with solitary tumors,9 of them occurred in the parotid gland region,one in the left occipital,one in the right forehead,one in the right parietal,and another one in the left eyelid.The maximal diameter of the tumors ranged from 0.6 to 2.3 cm with a mean of 1.5 cm.All lesions were well-circumscribed,with partial attachment to the overlying skin.Most of lesions were isodense relative to adjacent skeletal muscle on nonenhanced CT scans,sand-like or nodular calcifications within the masses were showed in 8 cases,and no cystic degeneration was found.On contrast-enhanced imaging,mild to moderate homogenous enhancement was showed in 3 cases,heterogeneous moderate enhancement with patchy nonenhancing necrosis area in one case,marked enhancement in one case,and complete calcification with no enhancement in one case.Conclusion Head and neck pilomatricoma presents with certain characteristics on CT,which are useful in the clinical diagnosis and differential diagnosis.