1.Management of electronic medical record
Journal of Medical Postgraduates 2003;0(11):-
It is an important object to manage current electronic medical history.Authors report the quantity management of electronics medical record, the history cases' legal effect and secrete management,the case's usage management and the case's safe management so as to increase the management quantity of electronics medical cases.
2.Problem and consideration in the evaluation of diagnosis
Journal of Medical Postgraduates 2004;0(01):-
The statistical index of diagnosis coincidence was the base for the evaluation of diagnostic quality. By the problem analysis of diagnostic coincidence assessing, we were to establish standard criteria uniform and strict methods of evaluation; to enhance diagnosis coincidence rate, and to make full use of statistical index.
3.Appliance of electric signature and related regulations in electric medical records
Dan ZHANG ; Fenghua LI ; Wanming FU
Journal of Medical Postgraduates 2004;0(02):-
Considering technology,regulations and other factors,nowadays we still use the records of print instead of in digital.《Electric Signature Law》makes a new environments for the study of electric medical records system.It regulates the writing,originally form and the save of electric medical records,affirms its value of evidence in court and prescribes what is dependable electric signature.
4.The construction of periodical quality and the management of medical quality
Li LU ; Wanming FU ; Weihong ZAHNG
Journal of Medical Postgraduates 2003;0(11):-
By analying the relationship between the construction of the periodical and the management of the medical quality, the author explained the positive effect of strengthening the former on level raising of the latter, She also proposes that the value of the periodical can be raised by the quality construction including superiority orientation and creativity development. In this way we will raise the additional value of the management of medical quality and provide a high-level information platform for the quality mangement of hospital.
5.On the problems of infringement on patients' privacy in medical activities
Caixia YANG ; Wanming FU ; Dan ZHANG
Journal of Medical Postgraduates 2003;0(11):-
In the recent years,infringement on patients' privacy in medical activities is drawing wider attention.In medical practice there exit some common phenomena of this kind,such as some medical staff spreading the information of medical record to irrelevant people,going beyond their duty to pry into or deliberately disclose patients privacy,intentionally harass of directly intrude upon patients' private parts,etc.These problems can be gradually reduced or avioded by strengthening medical staff's awareness of self-discipline,offering related education and advice to patients,and perfecting relevant laws and regulations.
6.Determination of catalpol in dried rehmannia root and Taohong Siwu Decoction with high performance liquid chromatography
Chunyan GUO ; Xuemei BAI ; Wanming ZHANG ; Zhibao WANG ; Yurong FU
Journal of Integrative Medicine 2004;2(2):135-7
OBJECTIVE: To determinate the catalpol contents in dried rehmannia root and Taohong Siwu Decoction containing rehmannia root with high performance liquid chromatography (HPLC). METHODS: Catalpol was separated on a YWG-C18 column using water-acetonitrile (99.4:0.6) as mobile phase and detective wavelength at 210 nm. RESULTS: The linear curve of tested catalpol concentration within the range of 0.0536-5.3600 microg/microl was ideal (n=5, r=0.999 7). The average recovery rate of the dried rehmannia root and Taohong Siwu decoction was 98.7% (RSD=0.48%) and 98.2% (RSD=1.29%) respectively. CONCLUSION: HPLC method is accurate and valuable for the quality control of Radix Rehmanniae and Taohong Siwu Decoction.
7.Determination of gallic acid and total phenolic acid in Sedum Aizoon L.
Yurong FU ; Wanming ZHAN ; Guimin CHEN ; Xuemei BAI
Chinese Traditional Patent Medicine 1992;0(07):-
AIM: To develop the methods for the quantitative analysis of gallic acid and total phenolic acid in Sedum Aizoon L. METHODS: Gallic acid was analyzed by HPLC on a Hypersil BDS C_(18) column and detected at 271 nm.The mobile phase was methol-water(adjusted to pH=3.0 with H_3PO_4)(90∶10)at a flow rate of 1.0 mL/min.Total phenolic acid was analyzed by spectrophotometry at 720 nm.The colour-developing agent was the mixture solution of 0.6%FeCl_3—0.9%K_3[Fe(CN)_6](1∶0.9). RESULTS: Calibration graphs were constructed in the range of 0.343 0-1.200 ?g(r=0.999 7) for gallic acid and 0.4640-2.320 ?g/mL(r=(0.999 3)) for total phenolic acid.The average recoveries were 97.91%(n=6) for gallic acid and 99.21%(n=6) for total phenolic acid.The RSD of the methods were 1.8% and 2.0%,respectively. CONCLUSION: The methods were fast,reliable,accurate and suitable for analysis of gallic acid and total phenolic acid and quality control in Sedum Aizoon L.
8.Factor analysis of quality guidelines for medical treatment
Junhao GUO ; Caixia YANG ; Wanming FU ; Yuxiu LIU ; Hui CAI
Journal of Medical Postgraduates 2003;0(06):-
Objective: To explore the potential influencing factors of the quality guidelines for medical treatment by factor analysis.Method: We analyzed with the SPSS package 9 quality guidelines for medical treatment in the department of integrated TCM and Western medicine of a hospital,including the out-patient person-time,the number of discharges,the average days of hospitalization,the rate of bed utilization,the frequency of bed rotation,the rate of cure and improvement,the case fatality rate,the coincidence rate of diagnoses at admission and discharge,and the success rate of emergency treatment.Results: Four common factors were extracted,namely,the quantifiable factor,determined by the out-patient person-time,the number of discharges,the average days of hospitalization and the frequency of bed rotation;the treatment factor,determined by the cure and improvement rate and case fatality rate;the diagnostic factor,determined mainly by the rate of bed utilization and the coincidence rate of diagnoses at admission and discharge;and the emergency treatment factor,determined by the success rate of emergency treatment.The cumulative contribution rate of the 4 factors was 85.1%.Conclusion: The amount of medical work,the techniques of treatment,the ability of diagnosis and the efficiency of emergency rescue are the main influencing factors of quality guidelines for medical treatment.
9.The summarization and analyze for our hospital’s articles collected by statistic source magazines for 15 years
Wanyu ZHANG ; Jun ZHENG ; Shuguang ZHANG ; Wanming FU ; Li LU ; Ya DING
Journal of Medical Postgraduates 2003;0(05):-
Objective: To explore the managemental essential ,we have Analyzed retrospectively 4635 articles collected by nation for 15 years in our hospital . Methods: According to the article database which collected our hospital's published articles from 1990-2004 provided by the center of article statistics and analyze of china science and technology institute of national department of science and technology, Windows Access 2000 was used to export articles, and Excel was used to sort﹑collect the results. Results: The embodied number was increased year by year , the authors were mainly from key department, clinical department with master or doctor degree and with high title of professional post, the condition of embodied articles is positive related with research level. Conclusion: It has validated the objective and meaning of the article management; and explained that the article is the talents strength expression,the science research platform,the science research management effects,the subject building collection and the symbol of connecting with the world .
10.Primary intracranial DICER1-mutant sarcoma: a clinicopathological analysis of seven cases
Liqiong OU ; Shaoyan XI ; Lingyi FU ; Wenguang ZHANG ; Xinyi XIAN ; Yanhui LIU ; Jingping YUN ; Jing ZENG ; Wanming HU
Chinese Journal of Pathology 2024;53(12):1231-1237
Objective:To investigate the clinicopathological features, immunophenotype, molecular characteristics, and differential diagnosis of primary intracranial DICER1-mutant sarcoma in order to better understand this tumor type.Methods:A retrospective analysis was conducted on 7 cases of primary intracranial DICER1-mutant sarcoma diagnosed in the Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou, China between 2021 and 2023 using next-generation sequencing. At the same time, 10 gliosarcomas, 4 intracranial FET::CREB fusion-positive mesenchymal tumors, 4 malignant meningiomas, 3 malignant solitary fibrous tumors, 3 malignant peripheral nerve sheath tumors, 3 synovial sarcomas and 3 rhabdomyosarcomas (total 30 cases) were selected as control.Results:Among the 7 patients with primary intracranial DICER1-mutant sarcoma, 6 were male and 1 was female, aged 10-32 years (median, 23 years). The tissue morphology was predominantly spindle or pleomorphic sarcoma-like, with 6 cases exhibiting eosinophilic globules, and 3 cases showing rhabdomyoblastic or rhabdomyosarcoma-like cell differentiation. Immunohistochemistry revealed focal desmin expression in 3 cases (3/7), ATRX loss in 3 cases (3/7), and p53 mutant pattern in 4 cases (4/7). Additionally, 4 cases (4/7) showed focal or diffuse SALL4 expression, whereas the control cases (30 cases) did not exhibit SALL4 protein expression, suggesting that SALL4 may possess certain auxiliary diagnostic value. Next-generation sequencing confirmed that all 7 cases of primary intracranial DICER1-mutant sarcoma harbored mutations in the DICER1 gene, with 5 cases having the mutation site at p.E1813D. Until May 2024, all 7 patients were alive.Conclusions:Primary intracranial DICER1-mutant sarcoma is a rare tumor. Understanding its morphological characteristics, immunohistochemical and molecular markers and differential diagnosis is crucial to avoid misdiagnosis and to improve diagnostic accuracy of this tumor.