1.Clinical study on effects of removing-stasis and resuscitating methods on conscious state of patients with severe cerebral injury
Jie ZHOU ; Wanmin CHE ; Kai LI ; Tao DONG ; Quanhua ZHAO ; Zhenxing MIN
International Journal of Traditional Chinese Medicine 2010;32(2):150-151
Objective To explore the effects of removing-stasis and resuscitating methods on patients with severe cerebral injury. Methods Retrospective analysis was performed with clinical data of 47 patients. All 47 patients were recruited into a control group(n=21) and a treatment group(n=26). The control group was treated with conventional western medicines; while the treatment group was additional treated with traditional Chinese medicine on the basis of the control group. Results The rate for resuscitation after one week's treatment was 73.08% and 57.14% in the treatment group and the control group respectively, showing significant differences (P<0.01). The total effective rate was 76.92% and 61.90% in the treatment group and the control group respectively, also showing significant difference (P<0.05) . Conclusion The method of removing-stasis and resuscitating can promote severe cerebral injury patients regain their consciousness, and improve their prognosis.
2.Influence of edaravone on hydrocephalus and prognosis of patients with moderate and severe traumatic brain injury
Kai LI ; Jie ZHOU ; Wanmin CHE ; Limei SONG ; Quanhua ZHAO ; Tao DONG
Journal of Clinical Medicine in Practice 2014;(16):128-130
Objective To observe the influence of edaravone on hydrocephalus and prognosis of patients with moderate and severe traumatic brain injury (TBI).Methods 124 patients with hy-drocephalus due to moderate and severe TBI admitted were randomly divided into treatment group (n =63)and control group (n =61).Routine treatment was given to control group,on which basis edara-vone was intravenously injected to treatment group.Hydrocephalus volumes before treatment and 3,7, 14 and 28 days after treatment,Glasgow Coma Scale (GCS)scores 28 days after treatment as well as Glasgow Outcome Scale (GOS)scores 6 months after follow up were observed.Results Hydroceph-alus volumes 3 and 7 days after treatment extended significantly than those before treatment in both groups (P <0.01),decreased apparently 14 and 28 days after treatment (P <0.01),and were smal-ler in treatment group than in control group (P <0.01 ).28 days after treatment,GCS scores in-creased significantly in both groups than those before treatment (P <0.01)and were higher in treat-ment group than in control group (P <0.01).6 months after follow up,GOS score was better in treat-ment group than in control group (P <0.05).Conclusion Edaravone can significantly reduce hydro-cephalus in patients with moderate and severe TBI and improve the prognosis.
3.Influence of edaravone on hydrocephalus and prognosis of patients with moderate and severe traumatic brain injury
Kai LI ; Jie ZHOU ; Wanmin CHE ; Limei SONG ; Quanhua ZHAO ; Tao DONG
Journal of Clinical Medicine in Practice 2014;(16):128-130
Objective To observe the influence of edaravone on hydrocephalus and prognosis of patients with moderate and severe traumatic brain injury (TBI).Methods 124 patients with hy-drocephalus due to moderate and severe TBI admitted were randomly divided into treatment group (n =63)and control group (n =61).Routine treatment was given to control group,on which basis edara-vone was intravenously injected to treatment group.Hydrocephalus volumes before treatment and 3,7, 14 and 28 days after treatment,Glasgow Coma Scale (GCS)scores 28 days after treatment as well as Glasgow Outcome Scale (GOS)scores 6 months after follow up were observed.Results Hydroceph-alus volumes 3 and 7 days after treatment extended significantly than those before treatment in both groups (P <0.01),decreased apparently 14 and 28 days after treatment (P <0.01),and were smal-ler in treatment group than in control group (P <0.01 ).28 days after treatment,GCS scores in-creased significantly in both groups than those before treatment (P <0.01)and were higher in treat-ment group than in control group (P <0.01).6 months after follow up,GOS score was better in treat-ment group than in control group (P <0.05).Conclusion Edaravone can significantly reduce hydro-cephalus in patients with moderate and severe TBI and improve the prognosis.