Objective To evaluate the value of high frequency color Doppler ultrasound in detecting the growth of orthotopic prostate tumor in nude mice. Methods Thirty-five orthotopic prostate tumor models of BALB/c nude mice were established. High frequency color Doppler ultrasound was used to monitor the growth of tumors in five randomly selected BALB/c nude mice after 2 - 8 weeks. After examination,the nude mice were immediately sacrificed under narcotism. The tumors were dissected, fixed and embedded. The sections were stained by HE and reviewed under microscope as the gold standard of detecting the growth of orthotopic prostate tumors. The growth curves were recorded and analyzed. Results High frequency color Doppler ultrasound can be used to observe the size, resonance, blood supply and necrosis of tumors. The tumors grew fastest in 4～6 weeks after injection. After seven weeks, necrosis can be found in the center of the tumors while the boundary of the tumor was not clear. Conclusions High frequency color Doppler ultrasound can be a reliable method to monitor the growth of orthotopic prostate tumor in BALB/c nude mice.

The standardized training of resident doctors is the main form of medical education after graduation. The standardization training of ultrasound doctors was guided by post competence, and was explored from the aspects, such as training target, teaching management, teaching method, teaching mode, and examination means. In this study, we adhered to the tutor responsibility system, and horizontal multi-module and vertical step-by-step teaching modes, made study plans according to local conditions, and improved the assessment system, so as to build a standardized and practical training system for ultrasound residents.

It is never an easy thing to diagnose heart vascular disease only depending on the unenhanced postmortem computed tomography (PMCT). This article reported a case of sudden natural death after the complaint of anterior chest pain in which coronary artery calcification (CAC) was clearly displayed using PMCT scan. The entire coronary artery system was almost reconstructed via multiplanar reformation (MPR) and volume-rendering reconstruction (VR), and the total calcium score of the coronary arteries was obtained with CaScoring automatic analysis software. The results showed that CAC was conspicuous; the total calcium score was 640.3, considerably higher than 400. The pulmonary ground-glass opacity (GGO) and small amount of fluid both in the subglottic trachea and main bronchi were also found. The imaging results confirmed those of autopsy. In addition, the results concluded that PMCT might serve as an invaluable adjunct to the classic autopsy procedure.
Autopsy ; Calcinosis/diagnosis* ; Cause of Death ; Coronary Artery Disease/diagnosis* ; Coronary Vessels/pathology* ; Death, Sudden/etiology* ; Forensic Pathology ; Humans ; Tomography, X-Ray Computed/methods*