1.Reading and displaying DICOM RT structure based on Matlab
China Medical Equipment 2016;13(6):5-7,8
Objective:To design a software to read and display CT and RT structure and draw a new contour without treatment planning system (TPS).Methods: In order to display the contour information drawn by doctors, the first step was to match CT images and RT structure then the same screen rendering of CT and RT structures could be applied. In order to add contour in RT structure obtaining the coordinates interactively, connecting coordinate points were the essential steps. Then a unique identity was given in the area of that contour to ensure its unique results. Results: The software successfully read and displayed CT and RT structures and drew a new contour without TPS.Conclusion: In this study, the software establishes a basis to improve the precision of the radiotherapy dose.
2.Comparison of the clinical effect of three types of drainage for treating malignant obstructive jaundice
Chinese Journal of Primary Medicine and Pharmacy 2013;20(14):2112-2114
Objective To observe the clinical efficacy of three types of drainage in the treatment of malignant obstructive jaundice.Methods 84 patients with malignant obstructive jaundice were selected,40 cases were treated with bridge drainage,24 cases were undergone percutaneous transhepatic cholangial drainage(PTCD) and 20 cases were treated with Roux-En-Y anastomosis.The changes of total bilirubin and direct bilirubin were detected 1,3,7 and 14 days after operation.Results The total bilirubin and direct bilirubin after 1,3,7 and 14 days had significantly decreased compared with pre-treatment(P <0.05),the decline rates in bridge drainage group were faster than the other two groups (P < 0.05).Conclusion The three types of drainage for treating malignant obstructive jaundice have exact effect,and the bridge drainage can reduce the bilirubin to lower levels more quickly than the other two methods.
6.Research progress of Bruton tyrosine kinase inhibitors in mantle cell lymphoma
Journal of Leukemia & Lymphoma 2016;25(6):377-380
Mantle cell lymphoma (MCL), is a disease with high heterogeneity, which is insensitivity to the chemotherapy and presents poor prognosis. Appearance of the Bruton tyrosine kinase (BTK) targeted inhibitors, such as ibrutinib, provides novel treatment strategy for MCL. This review focused on the latest achievements of BTK inhibitors in MCL treatment.
7.Clinical Observation on Rhubarb Enema and Glauber's Salt Topical Treating Acute Pancreatitis
Journal of Zhejiang Chinese Medical University 2015;(7):545-547,554
[Objective]To discuss the clinical efficacy of Rhubarb Enema and Glauber's salt Topical on acute pancreatitis.[Methods]Select in our hospital from April 2010 to April 2014 60 AP patients were randomly divided into two groups,n=30 for each.The treatment one was treated with Rhubarb Enema and Glauber's salt Topical on the basis of western medicine,the control group only received conventional western treatment.After 7 days,observe clinical symptoms and laboratory parameters changes,e.g.exhaust defecation, bowel sounds, serum amylase and C-reactive protein,and compare the two groups before and after the treatment of APACHEⅡand BISAP score. [Result] The clinical effective rate was 90% in treatment group and was better than the control group 73.33%,the difference was obvious(P<0.05). Treatment group patients exhaust defecation,bowel sounds were obviously improved,serum amylase,c-reactive protein index decreased obviously(P<0.05). APACHEⅡand BISAP score index decreased obviously(P<0.05), the difference was all obvious for the treatment group.But there's no significant statistical differences between before and after treatment for the control group(P>0.05). [Conclusion]Rhubarb Enema and Glauber's salt topical treatment for acute pancreatitis have a significant effect.
8.Explicit/Implicit Self-Esteem and Individual's Mental Health
Chinese Mental Health Journal 1989;0(03):-
Objective: To study the relationship between explicit/implicit self-esteem and mental health. Methods: 49 college students (including 26 male and 23 female, mean age 22) completed Rosenberg Self-esteem Scale and SCL-90. Their implicit self-esteem was measured by Implicit Association Test (IAT). Results: The results indicated a moderate to strong correlation between explicit self-esteem and mental health level. Yet the implicit indicator show insignificant influence on mental health. Conclusion: The study tends to support the hypothesis that implicit self-esteem is a independent structure from explicit self-esteem
9.A Meta analysis for 4250 portal hypertension cases undergoing surgery in Chinese literature
Zhengfeng WANG ; Guangwen ZHOU
Chinese Journal of General Surgery 2012;27(8):643-649
ObjectiveTo systematically evaluate the therapeutic effect of gastroesophageal devascularization( GD),portasystemic shunt( PSS),devascularization plus portasystemic shunt ( GD + PSS) for the treatment of 4250 cirrhotic portal hypertension cases reported in Chinese literature. MethodsThe literatures about the effect of gastroesophageal devascularization,portasystemic shunt,devascularization plus portasystemic shunt on portal hypertension were collected from Wanfang databases, China National Knowledge Infrastructure(CNKI) from 1980 to 2011.RevMan 4.2 and SPSS 13.0 were used for data analysis. ResultsIn this study 17 reports were enrolled into the meta-analysis.The results of the mta-analysis showed that long term survival rate in the group of GD plus PSS was higher than that in group of GD [OR=1.73,95%CI (1.23,2.44),P <0.01].That in group of PSS was similar with the group of GD [ OR =0.87,95 % CI (0.63,1.20),P =0.40 ].That of group GD plus PSS was similar with the group of PSS [ OR =1.73,95% CI (0.95,3.13),P =0.07 ].For recurrent variceal bleeding rate,that in group of PSS was lower than that in the group of GD[ OR =0.46,95% CI (0.35,0.61 ),P <0.01 ].That in the group of GD plus PSS was lower than that in the group of GD [ OR =0.25,95% CI (0.18,0.35),P < 0.01 ].The group of GD plus PSS was similar to that of group of PSS [ OR =0.72,95% CI ( 0.40,1.29 ),P =0.27 ].Encephalopathy rate was higher in the group of PSS than the group of GD [ OR =3.57,95% CI (2.43,5.23 ),P <0.01 ].That in group of GD plus PSS was lower than that in the group of PSS[ OR =0.37,95% CI (0.20,0.69),P <0.01 ],while that in GD plus PSS was similar to the group of GD[ OR =1.58,95% CI (1.02,2.43),P =0.04 ].ConclusionsThe only significant factor influencing the long term result in Chinese patients with portal hypertension is preoperative liver function.The three types of operation have different benefits and disadvantages.
10.Quality assurance strategy for HbA1c POCT
Chinese Journal of Laboratory Medicine 2014;37(12):896-898
At present,HbA1c is regarded as the gold standard in of the diagnosis of diabetes mellitus.Point-of-care HbA1c testing is popular used in China,however,the quality assurance of POCT HbA1c lags behind that of central laboratory HbA1c testing.The quality assurance strategy for POCT HbA1c must be taken into consideration.Strategies should include risk management,personnel evaluation,troubleshooting system,quality control,proficiency testing,method validation and calibration.