Acupuncture Points ; Child, Preschool ; Dyspepsia ; therapy ; Female ; Fever ; therapy ; Humans ; Male ; Massage

Objective Approach mammographic wire-localization biopsy technology's value in diagnose of dditescenee focus of infection about breast disease. Methods Utilizing specific purpose computer stereotaxis system, utilize mammographic wire-localization for 47 pieces delitescenee focus of infection about breast disease which can't be touehed in clinical ,at guide wire's leading exsect focus of infection and make molybdenum target for tissue by ex- cisional, then make patho-test when the focus of infection were completely resection. Results 45 patients have 47 pieces delitescence focus of infection,detaining 47 guide wire,all operations succeed only by once,and the focus of in- fection are completely resection,the correct rate of diagnose is 100% .The result of patho:13 cases are breast cancer and that have 14 pieces focus of infection,one of them is both sides,benign lesion are 32 cases and 33 pieces focus of infection. Conclusion The biopsy by mammographie wire-localization is convenient and accurate, can make sure the character of delitescence focus of infection about breast disease,which cart raise the rate of diagnosis in earlier period breast cancer.

Objective　To observe the effects of repeated subconvulsive electrical stimulations to hippocampus on rat's emotional behavior and spatial learning and memory. Mehtods　The hippocampus of Wistar rats were repeatedly stimulated by constant pulsating current with intratrain frequencies of 16 Hz, pulsating duration of 1 ms, train duration of 10 s and interstimulus interval of 7 min for 5 days. Results　The experimental rats displayed the long-term significant abnormalities of emotional behaviors, such as substantial changes of behavioral habits, hyperarousal, hypersensitive frightened reactions, anxiety-like behaviors, and transitory spatial learning and memory disorder. Conclusion　The stable and practical animal model satisfied most characteristics of posttraumatic stress disorder (PTSD).

Objective To explore the influence of adenoid hypertrophy on the state of the middle ear in children.Methods Two hundred and seventy two adenoid hypertrophy patients,aged from 2 to 12 years old,were examined with otoscopy,tympanometry and temporal bone computered tomography before adenoidectomy.The average age of the patients was 6.3 years old.These patients were divided into two groups:Group A contained 94 normal hearing patients(188 ears),Group B 178 patients(356 ears) containing of hearing loss.Results Out of the temporal bone computed tomography (CT) revealed that 209 patients(396 ears) had middle ear effusions in(72.79%,396/544ears),and 37 patients(65/188 ears,34.57%) hydrotympanum in Group A and 172 patients(331/356 ears,92.98%) in Group B.All the 396 ears effusion were confirmed by operation.Three hundred seventy three ears effusion were confirmed by the CT and operation in the two groups,377 ears with B type tympanogram(373/377,98.94%),93.85%(61/65 ears) in Group A,100%(312/312 ears) in Group B,respectively.The positive predictive value for middle ear effusion of the B-type tympanogram was higher in Group B than in Group A(P＜0.01).Fourteen ears with peak pressure ＜-200 daPa revealed hydrotyrnpanum and 23 ears with normal acoustic stapedius reflex revealed no fluid by CT and operation in 73 ears with C-type tympanogram.CT also revealed two patients suffered from large vestibular aqueduct syndrome and one with cochlear malformation in Group B.Conclusion Type B tracing tympanogram has a high positive predictive value for middle ear effusion in adenoid hypertrophy children.Type C tympanogram could not exclude effusion when the peak pressure is＜-200 daPa.CT is the best tool for identifying hydrotympanum.

Objective To discuss the community-based psychological support model for people living with HIV/AIDS. Methods A community-based psychological support team was set up. The team composed of psychology experts,community volunteers,community physicians,community nurses and family members of patients. It provided psychological care and emotional support to people living with HIV/AIDS through activities such as psychological counseling,health education,anti-discrimination advocacy and peer exchanges. Results This model significantly reduced the anxiety and depression,and increased life satisfaction of people living with HIV/AIDS(P<0.01). Conclusions The community-based psychological support model has more advantages than the traditional psychological support. It gives full play to the community on AIDS prevention and control functions,as well as has great significance to mobilize social forces to control the spread of AIDS.

Background and purpose: x-linked inhibitor of apoptosis (XIAP) is one of the crucial kinds of inhibitor of apoptosis protiens (IAPs) which belongs to an apoptosis-supressing factor family. It has been found that XIAP is significantly expressed in many kinds of tumor cells, and there is a correlation between XIAP expression level and chemoresistance. We aimed to study the relationship between chemoresistance and the expression of XIAP induced by gemcitabine (GEM) in pancreatic carcinoma cell line BxPC-3. Methods: The pancreatic carcinoma cell line BxPC-3 was incubated in DMEM, and the cells were treated with 3.10 μg/mL GEM for different sections (0, 24, 36, 48 and 72 h, 0 h was the contral group). Then changes of the cell cycle and apoptosis index were evaluated by flow cytometry, mRNA transcription and expression of XIAP were also examined by RT-PCR and Westem blot. Results: In control group the apoptosis rate was (1.23±1.6)%, while the apoptosis rates were (10.3±1.8)%, (14.2±1.5)%, (18.8±1.7)% and (20.3±2.0)%, respectively, in experimental groups, cell cycle analysis showed that G_0-G_1 phase arrest was induced by GEM, and there was a significant differences (F=146.24, P<0.05). But there was no significant difference in apoptosis rates between the 48 h and 72 h groups (P>0.05). We also found that the longer the cells were treated with GEM, the more mRNA transcription and expression of XIAP were detected (F=83.72, F=103.58, P<0.05). Between the 24 h group and 36 h group (P>0.05), which were different from the 36 h and 48 h groups, 48 h and 72 h groups (P<0.05), no significant differences were found in mRNA transcription and expression of XIAP. Conclusion: GEM could obviously inhibit proliferation and induce apoptosis of BxPC-3 cells, and drug sensitivity decreased with prolongation of exposure time. GEM might induce and increase the expression of XIAP, which might influence the apoptosis of the cells later, and the disturbance of apoptosis progression might have contributed to chemoresistance.

Long-term or even permanent neuronal injury can follow administration of general anesthetics.It has been confirmed that some elderly patients may experience a decline in cognitive function after general anesthesia.However,the effects of general anesthetics on the central nervous system have not been determined yet.Here we summarize the effects of general anesthetics on the central nervous system in pediatric patients and immature animals.

Objective To explore an effective treatment for knee osteoarthritis.Methods All patients were randomly recruited into an observation group(n=41)and a control group(n=37).The observation group was treated by warming needling.while the control group was treated by common acupuncture combined with TDP. Results The effective rate of the observation group and the control group was 90.24%and 70.27%respectively,showing significant difference(P<0.05).Conclusion The warming needling was effective in treating knee osteoarthritis.

Objective To evaluate the effects of intravenous anesthesia with propofol and fentanyl on flexible fiberoptic bronchoscopy (FFB).Methods Forty ASA Ⅰ - Ⅱ patients undergoing elective FFB were randomly divided into two groups (20 cases in each group): control group and intravenous anesthesia group.All patients received airway local topical anesthesia with 2% lidocaine before the procedure.The patients in intravenous anesthesia group received propofol 1.5 mg/kg and fentanyl 1 μ g/kg intravenous injection for induction while in control group normal saline was given instead.Supplemental oxygen was administered by the endoscopy face mask.The mean arterial pressure (MAP),heart rate (HR)and pulse oxygen saturation (SpO_2) were continuously monitored and recorded before induction of anesthesia (T_1, baseline), 1 min after intravenous injection (T_2) ,immediately and 3 min after intubation (T_3,T_4),after FFB (T_5).The persistence time of the procedure was noted.When the patients responded to commands exactly, the recovery time was recorded.All patients were interviewed for the global tolerance to the procedure, the acceptance of another fiberoptic bronchoscopy and the degree of amnesia.Results All of the 40 patients finished FFB successfully.VAS postoperation and dependence scores were lower in intravenous anesthesia group than those in contrel group[(1±2),(2±3) scores and (7±1),(7±3) scores](P< 0.05).MAP and HR at T_3, T_4 and T_5 were significantly increased compared with baseline values at T_1 in control group (P <0.05).MAP and HR at T_2 was lower than those at T_1,HR at T_3 was higher than that at T_1 in intravenous anesthesia group (P < 0.05 ).Compared with control group, MAP and HR at T_3, T_4 and Ts were lower, HB at T_2 was lower in intravenous anesthesia group (P < 0.05).There was no awareness during the FFB in intravenous anesthesia group.Conclusion Intravenous anesthesia with propofol and fentanyl is safe and effective for FFB.

Cystatin C (Cys C) is used to evaluate the glomerular filtration rate (GFR), renal function and thus reflects changes in endogenous marker. Cys C is not affected by gender, muscle mass, malignancy and its production rate is usually constant, making it one of ideal markes of GFR. This article focuses on clinical application and research of Cys C in a variety of renal diseases, especially in renal dysfunction at an early stage of clinical significance.