Objective To observe the clinical curative effect of Xuezhikang maintaining treatment for senile hyperlipidemia.Methods According to the digital table,96 elderly patients with hyperlipidemia were selected and randomly divided into the three groups.The control group 1 with 32 cases took orally rosuvastatin before sleeping 10mg per time,1 time /day,12 weeks one treatment course.The control group 2 with 32 cases took orally Xuezhikang capsule before sleeping 0.6g 2 times/day,12 weeks one treatment course.The treatment group with 32 cases took first orally rosuvastatin before sleeping 10 mg/time,1 time /day for 4 weeks,then changed to use Xuezhikang capsule 0.6g 2 times/day for six weeks.The total treatment course was 12 weeks.Results After treatment,TC,TG,LDL-C in three groups all declined significantly and HDL-C increased.The curative effect was similar in treatment group and control group 1 with no statistical difference(P >0.05).Conclusion Xuezhikang has similar efficacy with rosuvastatin 10 mg/time in hyperlipidemia,and recommand Xuezhikang clinical use for its lower price.

Citrin deficiency,caused by mutations in SLC25A13,is an autosomal recessive genetic disorder with two age-related phenotypes:adult-oneset type Ⅱ citrullinemia and neonatal intrahepatic cholestasis.Recently,it has been found mostly in individuals of East Asian ancestry.In south China,there is a high mutation carrier frequency especially.There is still a lack of criteria for clinical or biochemical diagnosis of this disease,gene analysis is the main basis of the current diagnosis consequently.Surging number of case reports indicate that Citrin deficiency is not a self-limited disease.Early diagnosis and proper treatments may improve the prognosis.This paper focuses on the current researches in order to make further comprehensiom.

Objective: To study the effect of fish-oil fatty emulsion on immunity of post-operation patients with malignancy tumors.Methods: Forty-three post-operation patients with malignancy tumors were randomly divided into control group and study group and both groups were provided with parenteral nutrition treatment [104.6 kJ(25 kcal/kg)].Fish-oil fatty emulsion was given to the study group.The level of serum albumin,immunity function,jaundice index,aminotransferase,blood lipid and morbidity rate of infectious complications of the two groups were compared.Results: After five days of post-operation treatment,in the study group,the immunity function was significantly improved and morbidity rate of infectious complications declined.The levels of serum albumin,the blood lipid,jaundice index,and aminotransferase had no significant difference between the two groups.Conclution:Fish-oil fatty emulsion is beneficial to the immunity function and can emilsion decrease infectious complications of post-operation patients with malignancy tumors.

This article introduces concept of quality of work life and analyses main factors influencing quality of teachers'work life. In order to stabilize emotion of teachers and retain excellent teachers,we put forward the suggestions for improving and enhancing the quality of teachers'work life.

During the whole process of rescue operations,the teleconsultation vehicle has not only realized long-range consultation function but also played a vital important role in emergency communication,propagation,contaction,etc.Its manifestation tracks out some practical methods for the emergency rescue operation hereafter.

To meet with the new problems of curriculum design about prevention medicine field to undergraduate in medical college,based on our teaching practice,we tried to explore some teaching measures about fieldwork of health education,in term of updating teaching methods and skills so as to enhance our students' integrated quality,cultivate and bring up more and more capable new-pattern preventive medical students fit for the public requirements.

OBJECTIVE:To establish a HPLC method for the determination of dolastron mesylate.METHODS:The sample was separated on Diamonsil C18 column.The mobile phase consisted of acetonitrile-water-1mol? L-1 ammonium formate(450∶ 440∶ 110)(pH=8.0 adjusted with trithylamine)with a flow rate of 1.0mL? min-1.The UV detection wavelength was set at 285nm and the sample size was 20? L.RESULTS:The linear range of dolasetron mesylate was 24～ 56? g? min-1(r=0.999 6),with average recovery at 99.7%(RSD=0.74%).CONCLUSION:The established is simple,sensitive and reproducible,and suitable for the quality control of dolasetron mesylate.

Objective To investigate the effects of Wuling Powder on insulin resistance of C57BL/6J mice induced by high lipid diet, and discuss the mechanism. Methods C57BL/6J mice were randomly divided into six groups:normal group, model group, rosiglitazone group, Wuling Powder in low, middle, and high dose groups, 10 mice per group. Besides the normal group, other five groups were fed with high fat and sugar diet, with a purpose to establish insulin resistance model. Normal group and model group were given pure water. Rosiglitazone group received a gavage with rosiglitazone of 0.75 mg/kg. Wuling Power low, middle, and high groups received gavage with Wuling Power of 1.23, 3.69, 11.07 g/kg, respectively, the does volume was 0.2 mL/10 g, once a day. The weight and abdominal girth were detected every week. At the end of the sixth week, mice were given 12-hour fasting, and their eyeball were taken for blood. The body weight, length, and fat in abdomen and both kidneys were detected. Paraffin section was made with HE staining. FPG and FINS of each group were detected. ISI and IRI were calculated, and TC and TG were detected. Results Compared with the model group, Wuling Powder can significantly reduce the body weight and abdominal girth of mice (P<0.01, P<0.001), improve liver fatty degeneration, lower the FPG, FINS, TCH, TG, IRI, and increase the ISI in mice (P<0.05, P<0.01). Conclusions Wuling Powder has the effect of preventing insulin resistance of C57BL/6J mice induced by high lipid diet.

ObjectiveTo analyze the influencing factors of the blood pressure fluctuation during the perioperative period of pheochromocytoma,and discuss the ways to improve the hemodynamics.Methods The clinical data of patients with pheochromocytoma who had received operation from 2000 to 2010 werestudied retrospectively.The influencing factors of perioperative blood pressure fluctuation were analyzed by statistical methods including Pearson correlation analysis and Logistic regression.ResultsAccording to Pearson correlation analysis,the influencing factors of the highest fluctuation value of the systolic blood pressure ( △ SBP) during the operation included the preoperative highest systolic blood pressure (r =0.196,P =0.013 ),the content of preoperative 24-hour urine epinephrine ( r =0.207,P =0.008 ) and the lost blood volume during the operation (r =0.253,P=0.003).Logistic regression analysis showed that the postoperative persisting hypotension was influenced by the content of preoperative 24-hour urine norepinephrine(OR =1.273,P =0.002) and preoperative preparation duration(OR =0.921,P =0.034);the risk factors of postoperative hypertension were residual tumor (OR =16.920,P =0.001 ) and the preoperative hematocritchange(OR =1.467,P =0.018).ConclusionsIn spite of the adequate preoperative preparation,great changes of blood pressure would still occur during the perioperative period of pheochromocytoma,and it is influenced by many factors.Corresponding measures aiming to these factors should be taken to decrease the perioperative blood pressure fluctuation and surgical risks.

ObjectiveTo investigate the feasibility of apphcation of risk factors management in nursing of the fever outpatient.Methods145 patients from May to December 2009 admitted to fever clinic was defined as the control group, 157 patients from January to May 2010 admitted to fever clinic were set as the observation group. The control group was given routine nursing, while the observation group adopted risk factor management measures. The management indices of the two groups were compared.ResultsThe patients' recognition score of risk factors of fever clinic was (85.4 ± 2.7)in the observation group, higher than(73.2 ± 3.9)in the control group. Patients' satisfaction degree was 84.7％ in the observation group, higher than 67.6％ in the control group. Rate of risk event of the observation group was 1.3％, lower than 6.2％ in the control group, the incidence of nursing errors was 0.6％ in the observation group, lower than 4.1％ in the control group, rate of patients' complaints of nurses was 1.3％ in the observation group, lower than 5.5％ in the control group.ConclusionsThe implementation of risk factors management in fever clinics can reduce medical accidents, improve nursing quality, so this clinical management mode deserves promotion and application.