Objective To study the significance of acute pancreatitis AP complications by acid-base distur-bance. Methods The arterial blood gas, serum electrolytes parameter and clinical data of 85 patients were analyzed.Results Acid-base disturbance of different types commonly existed in the early stage of AP patients. There are sig-nificant statistical differences in the indices of PaO2, PaCO2, SaO2 between group MAP and group SAP( P < 0.05 or P < 0.01 ). Conclusion Acid-base disturbance are very common in the AP patients and this-will make the condition worse,they should be treated promptly.

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Skin toxicities are the most common adverse effects of epidermal growth factor receptor inhibitors(EGFRI).It can result in significant physical and psyehological discomfort,and even leads to interruption or dose modification,and consequently affect the curative effect. Nowadays this adverse effect has attracted lot of attention.It is proposed that clinical management and treatment measures for skin toxicities should be further studied to improve the patients life quality,and guarantee the continuity and best curative effect of the treatment.But more researches on the pathogenesis and its prognostic significance are still expected.

ObjectiveTo revise the Chinese version of the screening for somatofonn symptoms-7( SOMS-7).Methods——( 1 )306 patients with somatoform disorder were selected in Psychiatry Clinic of Shengjing Hospital of China Medical University.(2) With convenient sampling,207 residents were selected in Xian village of Xintang town of Zengcheng district in Guangzhou and 288 in Tongji Road community of Chancheng district in Foshan.Besides,283 residents were selected in Changnan Community of Huanggu District and Jixiang Community of Dadong District in Shenyang.After 10 to 14 days,63 female and 73 male of the community subjects were selected randomly to fill in the scale again.All of the subjects filled in the Chinese version of the SOMS-7.Results ( 1 ) The internal consistency of the Chinese version of the SOMS-7 was 0.944 for female and 0.945 for male.The test-retest reliability was 0.869 for symptom count and 0.823 for severity index.The correlation with somatization subscale of SCL-90 was 0.805 for symptom count and 0.824 for severity index.(2) Based on the diagnostic criteria of somatoform disorder in DSM-Ⅳ,ROC curves were drawn.The AUC was 0.935 for symptom count and 0.942 for severity index in female,while 0.916 for symptom count and 0.926 for severity index in male.When 2.5 (female) or 1.5 (male) was chosen for symptom count and 15.5 (female) or 14.5 (male) for severity index,the youden in-dex reached a maximum.ConclusionThe Chinese version of the SOMS-7 showed a good reliability and validity,being reliable and valid as a tool to screen patients with somatoform disorder.

Objective To compare the efficacy of 10-day sequential therapy (including rabeprazole amoxillin clarithromycin tinidazole) and 7-day traditional trigeminy therapy (including rabeprazole amoxillin and clarithromycin) in patients with duodenobulbar ulcer and Hp infection. Methods Ninty-five patients with duodenobulbar ulcer and Hp infection were enrolled into the study and divided into two groups randomly:sequential therapy group and traditional trigeminy therapy group. Patients in the first group received 10-day sequential medications:rabeprazole 10 mg plus amoxillin 1 g for the first 5 days,followed by rabeprazole 10 mg plus clarithromycin 500 mg and tinidazole 500 mg for another 5 days;while in the second group patients received the standard 7-day traditional triple medications:rabeprazole 10 mg plus clarithromycin 500 mg and tinidazole 400 mg. All drugs were given twice daily. All patients received rabeprazole 10 mg daily following the two types of therapys for another four weeks. Hp statuses were assessed by rapid urease test and 14C urea breath test at baseline and 4 weeks after completion of the treatment. Ulcer cicatrization was assessed by gastroscope. Results The eradication rate of Hp infection was significantly higher in sequential group than triple group (89.5%vs. 70. 2%, P ＜ 0. 05 ), but we found no statistically significant difference in the comparison of the ulcer cicatrization rate between sequential group and triple group ( 87.5% vs. 82. 9%, P ＞ 0. 05 ). Conclusion Sequential therapy had a better Hp eradication effect than standard triple therapy, but the eradication rate was very close between the two therapys.

Objective To investigate the potential complications of renal transplant patients, to develop appropriate treatment programs to reduce the incidence. Methods Clinical data of 42 patients with renal transplantation were retrospectively analyzed. Blood type of the donors and recipients were same in 32 cases; Blood type of the donors was 0 and recipients blood type was A,3 cases;Donors blood type was 0 and recipients blood type was B,2 cases; Donors blood type was O and recipients blood type was AB,4 cases; Donors blood type was B and recipients blood type was AB,lease. Results In alll cases, there were acute rejection in 2 cases,pulmonary infection in 2 cases, wound infection in 1 case,urinary leakage in 1 case,urinary tract infection in 2 cases.42 cases were all cured up. One patient lost kidney function and required dialysis therapy 4 years after kidney transplantation, the remaining 40 patients were good. Conclusion Early detection and timely management of complications of renal transplantation played a very important role in improving the survival rate.

Objective To compare effects between the laparoscopic surgery and open surgery for the bigger adrenal adenoma(＞4cm) patients in Qinghai.Methods Altogether 57 cases of bigger adrenal adenoma patients(＞4cm)in the affiliated hospital of Qinghai university and Qinghai People's Hospital from 2012 to 2016 were selected and divided into two groups (A and B) according to surgical programs difference.Group A (23 cases)wcre givcn laparoscopic surgcry and Group B (34 cases)were given open surgery (And 2 cases in group A turned into open surgery were out of statistics).The operative time,blood loss,hospital stay and drainage tube removal time were compared.Results The operative time,blood loss,hospital stay and draiuage tube removal time in Group A were significantly better than those in Group B,with statistical significance (P ＜ 0.05).Conclusion The use of laparoscopic surgery for the bigger adrenal adenoma(＞4cm) patients is safer and more effective than open surgery.

Objective: To investigate the the sleep quality of frontier armymen located in the Gobi desert and its corre- lated factors. Methods: The sleep quality of 302 frontier armymen located in the Gobi desert was assessed with Pittsburgh Sleep Quality Index (PQSI). Results: The total scores of PQSI was 6.79?3.39,and 49.7% of the armymen suffered from sleep problems.The total scores of PQSI were correlated with health status,satisfaction with work,influence by the relation- ship with opposite sex,pressure from study and work,et al. Conclusion: The sleep quality problem of the frontier armymen located in the Gobi desert was more than normal people, and special measures should be taken to improve their sleep quality.

Objective To improve the diagnosis and management of closed renal trauma,and to reduce the rate of nephrectomy. Methods A total of 189 cases (146 men and 43 women; mean age,38 years) of closed renal trauma were retrospectively studied. A variety of examinations, including urinary analysis, B-ultrasonography, intravenous urography( IVU) and CT,were used for the diagnosis in these patients. Among them,closed renal trauma was accompanied by celiac viscera injury in 27 cases,by encephalic injury in 5, by fractures of spine and limbs in 13,and by compound trauma and shock in 3. Of the 189 cases, 156 were treated with conservative therapy, including 3 of spleen rupture,2 of encephalic injury,7 of fracture of spine and limbs;27 cases were treated with operation, including 15 with kidney repair,5 with partial nephrectomy, 7 with nephrectomy;3 cases were treated with selective renal artery embolization. Results Three patients with severe closed renal trauma died of compound trauma and shock soon after admission,and the other 186 patients recovered. Of them, 102 cases were followed up from 3 months to 8 years. Among patients undergoing conservative treatment renal hypertension occurred in 3 cases, urinoma in 1 , kidney atrophy in 1 and local hydronephrosis in 1. In patients undergoing surgery or selective kidney artery embolization, no subsequent complication occurred. Conclusions CT scan can provide a major basis for the diagnosis and treatment choice as well as early detection of urinoma of closed renal trauma. For closed renal trauma below grade IV ,conservative treatment is the better option.

Objective To investigate the feasibility and safety of laparoscopic surgical treatment of ulcerative colitis(UC).Methods The clinical data of 5 cases who underwent laparoscopic surgery for the treatment of ulcerative colitis were reviewed.Results All 5 cases successfully underwent laparoscopic surgery.Among them,4 had total proctocolectomy and ileal pouch-anastomosis(IPAA),and 1 had subtotal colectomy plus total proctectomy,and cecum-anal anastomosis.The median operating time was 7.5(6.5-9)h,the median blood loss was 250(150-400)mL,the median time to begin semi-fluid intake after operation was 62(60-86)h,the median time of hospital stay was 12(10-14)d,Postoperative pelvic infection occurred in 1 case,adhesive intestinal obstruction occurred in another case.The median follow-up time was 22(10-34)months,and the average number of daily bowel movement was 6.5(4-10)d;they were relapse-free,and had normal daily living and work at follow-up.Conclusions Laparoscopic surgical treatment of ulcerative colitis is associated with minor trauma and rapid recovery,and is safe and reliable,but further accumulation of cases is required.