The latest literatures on eslicarbazepine acetate in the treatment of epilepsy from home and abroad were referred. The results showed that the oral absorption of eslicarbazepine acetate is quick with long half life, linear pharmacokinetics and low potential of drug-drug interactions. Compared with carbamazepine and oxcarbazepine, eslicarbazepine acetate is more effective against epilepsy.

Referred to the latest literatures on raltegravir from home and abroad, the effect and safety of raltegravir in the treat-ment of AIDs were reviewed. The results showed that raltegravir was a necessary component for the initial treatment and repeated treat-ment of AIDs. Up till now, there was no report on its serious adverse reactions and drug interactions.

Objective To observe the clinical efficacy of therapy of nourishing kidney and liver for the treatment of hypomenorrhea with the syndrome of kidney deficiency and liver stagnation. Methods Fifty-one hypomenorrhea patients with the syndrome of kidney deficiency and liver stagnation were randomized into treatment group(N =25) and control group (N = 26). The treatment group was treated with oral use of Yangyin Shugan Capsules (mainly composed of Radix Bupleuri, Radix Paeoniae Alba, Radix Rehmanniae Preparata, and Fructus Ligustri Lucidi). The control group was given placebo capsules orally. After treatment for 8 weeks , the overall efficiency and therapeutic effect on menstruation of the two groups were evaluated according the changes of traditional Chinese medicine(TCM) symptom scores. Results(1) The total effective rate of the treatment group was 84.0％, and that of the control group was 15.4％, the difference being significant between the two groups (P < 0.01). (2) The effective rate on the menstrual volume and menstrual color and texture of the treatment group was 64.0％, 68.0％, and that of the control group was 7.7％, 15.4％ respectively, the difference being significant(P < 0.01). However, the difference of effect on improving menstrual period was insignificant between the two groups (P > 0.05). Conclusion Therapy of nourishing kidney and liver is effective for the treatment of hypomenorrhea with the syndrome of kidney deficiency and liver stagnation, and has obvious effect on improving menstrual volume and TCM symptoms.

Objective To align the mapping points from the locations of catheter electrodes with CT/MR image three-dimension data of the cardiac chamber. Methods Most of existing algorithms assumed that two spaces spanned respectively by mapping points and by CT/MR data were orthogonal, and thus modulated only 9 free-degrees of three-dimension translations, rotations and scaling for registration. However, our research showed that the above two spaces might be not always orthogonal. So we introduced affine transformation model based on 12 free-degrees and the corresponding iterative closest point algorithm to realize the registration and further incorporate the registration algorithm with the clinical operations. Combining with OpenGL, we realized the proposed algorithm via Visual C]+]+ 6.0 software. Results Simulation results showed that the residual registration errors on average were decreased from 40 pixels before registration to 1.5 pixels after registration. This algorithm was further validated in animal experiments. Conclusion This proposed three-dimension mapping registration algorithm well realizes the registration in three-dimension cardiac mapping and has practical application values.

Objective To investigate clinical efficacy of different ventilator parameters on acute left heart failure.Methods One hundred and nineteen patients with acute left heart failure were randomly divided into A,B,C,D group.Patients in A,B,C,D groups were treated separately with higher air pressure,high pressure,medium pressure or low pressure respectively.In each group,clinical efficacy,heart rate (HR),arterial partial pressure of oxygen (PaO2),pulse oxygen saturation (SpO2),partial pressure of carbon dioxide (PaCO2) and pH were measured.Results There were significant differences among the four groups in terms of HR,PaO2,SpO2,PaCO2 and pH (F =32.21,29.46,12.34,36.47,18.38 ; P ＜ 0.05).Compared with that in A,C and D group,the levels of HR,PaO2,SpO2,PaCO2 and pH in B group were significant difference (P ＜ 0.05).Meanwhile those indices in B group were difference among before and after treatment (t =12.25,13.46,8.75,9.83,2.58 ;P ＜ 0.05).The efficacy rates of four groups were significant different (x2 =0.97,P =0.012),and in B group was 93.1％,higher than that of other 3 groups(71.0％,65.6％,51.8％ ;P ＜0.05).Condusion The ventilator parameters(10-15 cmH2O,55％-75％ FiO2 at beginning and later revised the FiO2 to 30％-40％) was proved to be worthy in treating acute left heart failure.

Discussed in the paper are case-based payment practice in China,and outcomes of this practice for the past ten years.The authors pointed out that compared with DRGs,such a practice is exposed to such risks as low coverage of diseases,incompatible policies,defective pricing method,and lack of comprehensive evaluation.It indicates that China is on the initial stage of case-based payment reform which should be promoted with reference to international experiences.

Objective To study the clinical efficacy of treatment of atrophic scars of facial hemangioma after isotopes radiotherapy with micro-plasma.Methods A total of 52 patients with atrophic scars were selected under micro-plasma treatment for 4 times,one time every six weeks.And their efficacies were evaluated by compared with single standard of that before and after the treatment.Results By means of rate of clinical index,the total effective rate of atrophic scars was 82.7％.The degree of improvement was as follows:cured in 53.8％,marked effective in 28.9％,effective in 17.3％ and no case ineffective.The total effective rate of hyperpigmentation was 90.3％,including cured in 59.6％,marked effective in 30.8％,effective in 9.6％ and no ineffective cases.Conclusions Micro-plasma is an effective therapy for atrophic scars of facial hemangioma after isotopes radiotherapy,which can significantly improve the depression degree of scars,eliminate the hyperpigmentation and improve the color of scars,but it only has adverse reactions of wound pain and postoperative wound erythema.

OBJECTIVE:To observe the efficacy of the reduced glutathione against hepatic lesion induced by antituberculotic agents.METHODS:A total of 226 patients with pulmonary tuberculosis undergoing short- course chemotherapy were randomly assigned to receive antituberculotic agents plus reduced glutathione throughout the course(treatment group,n = 114 cases) or to receive Inosine plus Glucurolactone(control group,n = 112).The patients were followed for 3～6 months with the incidence of hepatic lesion compared between the two groups.RESULTS:There were significant differences between the treatment group and the control group in the incidence of hepatic lesion,6 cases(5.3%) in treatment group vs.29 cases (25.9%) in the control group(P

Objective To compare efficacy of indirect immunofluorescence (IFA) and real‐time fluorescent polymerase chain re‐action(PCR) in detection of mycoplasma pneumonia in children .Methods A total of 137 children clinically diagnosed as Mycoplas‐ma pneumoniae(MP) infection were selected and divided into groups by age ,including <1 years old group(35 cases) ,1- <5 years old group(69 cases) and 5-15 years old group(33 cases) .Blood specimen and throat swabs were collected and detected by using IFA and real‐time fluorescent PCR .At the same time ,all of the selected children were treated with conventional therapy ,according to total effective rate ,positive coincidence rates of the two methods were statistically analysed by age .Results The positive coinci‐dence rates in children with MP infection <1 years old and 1- <5 years old detected by using real‐time fluorescent PCR were high‐er than that detected by using IFA ,while among children 5-15 years old ,the positive coincidence rate was higher detected by using IFA compared with that detected by using real‐time fluorescent PCR ,all had statistically significant differences (P<0 .05) .The o‐verall positive coincidence rates of the two methods were not significantly different(P>0 .05) .Conclusion IFA and real‐time fluo‐rescent PCR both could be used as effective methods for detecting MP ,but there are some differences of detective efficacy between the two methods in each age group .Therefore ,it is suggested that for children under 5 years old real‐time fluorescent PCR might be selected ,for children aged 5 years old and over IFA might be selected ,in order to improve the detection accuracy and provide better guidance to clinical medication .