Pterygium is a common ocular surface disorder that has high rate of prevalence and recurrence. Currently, its pathogenesis is still unclear. Scholars agree that it's relevant to joint action of many factors. With the development of molecular biology, genetic and molecular studies concerning the pterygium achieved a breakthrough progress. Now the development of study in the pathogenesis of pterygium is reviewed in this paper.

Objective To investigate the long-term effects of early exposure to general anesthesia and surgery on children's intelligence and sensory integration function.Methods One hundred children who received general anesthesia and non-neurosurgery and non-cardiac-chest surgery operation (anesthesia group),were divided into one time anesthesia and multiple anesthesia.Fifty healthy children who did not receive general anesthesia and operation were as control group.There was no significant difference between 2 groups in sex,age,educational background etc.The Wechsler intelligence scale for children-fourth edition (Chinese version) and the child sensory integration check list were used to evaluate the intelligence and sensory integration function of the 2 groups.Results In development of intelligence,there was no significant difference between 2 groups in full intelligence quotient,verbal comprehension index,perceptual reasoning index,working memory index,processing speed index,general ability index and cognitive productive index.In intelligence structure,the incidence of clinically meaningful difference between verbal comprehension index-working memory index was significantly higher in anesthesia group one time and multiple anesthesia than that in control group [12.0％(6/50) and 26.0％(13/50) vs.6.0％(3/50),P ＜0.05].There was no significant difference in the incidence of sensory integration dysfunction between 2 groups.However,in anesthesia group,the incidence of vestibule balance dysfunction in multiple anesthesia was significantly higher than that in one time anesthesia [44.0％ (22/50) vs.22.0％ (11/50),P ＜ 0.05].Conclusions In general,general anesthesia and surgery during the first three years of life has no significant long-term effects on children's intelligence and sensory integration function.However,the incidence of clinically meaningful difference between verbal comprehension index-working memory index increases in the anesthesia children.Children who received multiple anesthesia and surgery during the first three years of life have a higher incidence of vestibule balance dysfunction.

With the wide application of digital technique in dental clinic,the virtual articulator has become an important tool of CAD/CAM systems for dental labs.The presented article introduces the classification,advantages and setting parameters of the virtual articulator.The authors also comment on the current commercial products of the virtual articulators in the domestic market.

Anniversaries and Special Events ; Authorship ; China ; History, 20th Century ; History, 21st Century ; Pathology ; history ; Periodicals as Topic ; history

Biomarkers ; analysis ; Gene Expression ; Gene Expression Profiling ; Genes, Viral ; Humans ; Pathology ; SARS Virus ; genetics ; Sequence Analysis, DNA ; Severe Acute Respiratory Syndrome ; genetics ; virology

Prof Yan(1920-)is one of the first batch of National Famous Traditional Chinese Doctors conferred by the national government.He is a well-known clinical physician and educator in TCM.He also is the representative inheritor of National Intangible Cultural Heritage Project conferred by Ministry of Culture.Prof YAN as one of a few prominent doctors is now still persisting in clinic.He did great contribution to development of TCM.The author,as his academic inheritor,followed his clinical practice for years and understood his academic thoughts from mouth-heart-teaching.Then the author summarized his clinical experience and strategy of prescription.The article may be a reference for inheritance of Prof Yan's academic thoughts.

Professor YAN Zheng-hua is a state-level renowned old doctor,intangible cultural heritage heir and educator ofTCM.He has made an outstanding contribution to the development ofTCM and Pharmacy.At present, Professor YAN Zheng-hua adheres to practicing in clinic although he is over 90 years old.He emphasizes"deficiency and excess"as the key link and‘qi,blood,cold,hot,deficiency,excess'as the global principle to treat stomachache.In clinical practice, Professor YAN Zheng-hua is expert in using famous TCM prescriptions such as Xiangsu San, Zuojin Wan,Yiguan Jian etc.flexiblly under the consideration ofsymptoms and syndrome.

Professor YAN Zheng-hua is a state-level renowned veteran TCM doctor,intangible cultural heritage and educator of TCM.He has made an outstanding contribution to the development of TCM and Pharmacy.At present,Professor YAN Zheng-hua adheres to practice in clinic although he is over 90 years old.He considers 'wind-cold,wind-hot,dampness and summer' as the main four categories of cold disease.In clinical practice,Professor YAN Zheng-hua likes using famous TCM prescription such as Jingfang Baidu San,Xiangsu San,Yinqiao San,Huoxiang Zhengqi San,etc.flexiblly under the comprehensive consideration of symptoms and signs.

AIM: To investigate the epidemiological characteristic and causative factors of anaphylactic shock caused by Shuanghuanglian Injection(Flos Lonicerae Japonicae,Radix Scutellariae,Fructus forsythiae). METHODS: Domestic medicine periodicals were searched between 1978 and 2005,and 72 cases with anaphylactic shock caused by Shuanghuanglian Injection were analysed by literature metrologic method. RESULTS: There were large proportion of young sufferers from age 18 to 44 in the case reports,and male 52.11%,female 47.89%,the primary affections were mainly upper respiratory tract infection,the occurrence of ADRs was commonly within 30 mins after injection,seven patients died of the terrible anaphylactic shock. CONCLUSION: Shuanghuanglian Injection may induce dangerous,even fatal anaphylactic shock,its mechanism includes many factors,such as patient's physical constitution.

Objective To investigate the characteristics of apparent diffusion coefficient (ADC)values in the normal fetal kidney and to explore the normal data reference of fetal kidney by using diffusion-weighted imaging (DWI).Methods 71 normal kidneys of fetuses confirmed by ultrasound and MR were examined with DWI with four b values of 100 s/mm2 ,200 s/mm2 ,500 s/mm2 and 700 s/mm2 ADC values of the symmetrical ROIs were compared between left and right kidney for each b value.While ADC values between different group in ipsilateral kidney were compared between different b values.And the relationship between ADC values and gestational age was also evaluated.Results When b = 100 s/mm2 ,there was a statistically significant difference between the ADC value of left and right kidney,and the remaining group showed no statistically significant differences between the ADC values of left and right kidney.Comparisons among different b values of ipsilateral kidney showed statistically significant differences among the groups with different b values except the comparison between b=100 s/mm2 and b=700 s/mm2 groups of the right kidney with the increase of gestational weeks,the ADC values of bilateral kidneys were declining,and there was a reflection of this trend in different b values. Conclusion It is feasible for using DWI to evaluate the fetal kidney development.With a selected different b value,ADC value is a specific quantitative parameter that could help evaluating normal fetal kidney development.