Acupuncture Therapy ; Adolescent ; Female ; Humans ; Olfaction Disorders ; physiopathology ; therapy ; Smell

Acupuncture and Moxibustion Therapy as a bridge between theoretical courses and clinical practice of acupuncture and moxibustion, is important. As the main part ofAcupuncture and Moxibustion Therapy, the training course deals with case analysis, inquiry training and simulation, clinical treatment ability training etc, in order to realize seamless docking classroom and clinical.

OBJECTIVE: To provide reference for the control of drug costs in China. METHODS: Present problems on drug were analyzed. The measures and effect of market mechanisms and policy interventions were analyzed referring to foreign experience on the control of drug expenses. RESULTS & CONCLUSION: Because drugs are a special kind of commodity, the combination and complementarity between market mechanisms and policy interventions can effectively control drug costs.

Objective To observe the clinical effect of treating refractory ascites by intermittent cycle ascites reinfusion.Methods Having 30 refractory ascites patients of both chronic renal failure and maintenance hemodialysis(MHD),treating them 102 times by intermittent close ascites reinfusion and synchronous hemodialysis,having reinfusion ascites 3000～5000ml each time,checking the change of serum creatinine(Scr),blood urea nitrogen(Bun),and serum albumin before and after hemodialysis(HD) by blood-test,and observing their temperature,weight,belly size,blood pressure,and pulse before and after treatment.Results After treatment,all the patients feel well,have good appetite,and have less swollen belly.The average treatment is 3.2 times.The table shows the patients' weight,belly size,serum albumin,serum creatinie and blood urea nitrogen(Bun) before and after treatment.The difference is obviously distinctive(P

Bone Neoplasms ; Chondrosarcoma ; Female ; Humans ; Middle Aged ; Nasal Cavity ; pathology ; Nasal Septum ; pathology

Biomarkers ; Carcinogens ; Epigenesis, Genetic ; Humans

Many researches show that the prognosis of gastrointestinal stromal tumor (GIST) are relatedtonumerousvariationsofbiomarkerssuchasnumericchromosomalaberrationsor nuclear/mitochondrialmicrosatelliteinstability.Inaddition, thechangesofproto-oncogeneand tumor-suppressor gene are found to influence the prognosis of GIST.The kit and platelet-derived growth factor receptor gene mutation are correlated with GIST progression,metastasis and targeted drug sensitivity,and then influence the prognosis of GIST.

Pancreatic cancer is a commonly malignant gastrointestinal tumor with an obviously increasing incidence all over the world.Those patients without specific symptoms at early stage had mostly lost the opportunity of surgical therapy when pancreatic cancer was detected at advanced stage,and their prognosis is poor.Therefore,it is rather crucial to improve the early diagnosis of pancreatic cancer.Tumor marker is a considerable tool for early tumor detection and screening.It will help to improve the diagnostic rate of early pancreatic cancer and promote the prognosis of pancreatic cancer if we could find out tumor markers and screen one or a group of pancreatic cancer tumor markers.

Aim ToinvestigatetheexpressionofMT1 in the hippocampus and serum melatonin in the asth-matic rats, and explore the mechanism in the develop-mentofasthma.Methods SixtyadultSDratswere randomly divided into two groups: control group ( n=20 ) and asthma group ( n=40 ) . Asthma rat model was established by sensitization and stimulation with ovalbumin ( OVA ) . Immunohistochemistry, Western blot, and reverse transcription PCR ( RT-PCR ) were used to evaluate the expression of MT1 in hippocam-pus. Enzyme linked immunosorbent assay ( ELISA ) was used to detect serum melatonin level. Results TheexpressionofMT1inhippocampusatgeneand protein levels were significantly elevated in asthmatic group ( P <0. 05 ) compared with the control group,whereas serum melatonin was obviously reduced ( P<0. 05 ) . Compared with day 5 and day 10 in the asth-matic group, there was a significant increase of MT1 in hippocampus on day 17 ( P<0. 05 ) , while there was no significant difference between day 5 and day 10 ( P>0.05).Conclusions MelatoninandMT1maybe involved in the pathogenesis of asthma. The up-regula-tion of MT1 in hippocampus with time-dependent pat-tern may be a compensatory response to decreased pe-ripheral melatonin levels for augmenting melatoninˊs neuroprotective and neuroimmunomodulatory effects a-gainst inflammatory reaction and stress in asthma.

Neonatal hypoxic-ischemic brain damage (HIBD) is a complex disease process in which injury severity,duration and timing of the antenatal injury are difficult to discern.HIBD triggers a cascade of pathophysiological events (blood-brain barrier damage,oxidative stress,inflammation,glutamate excitotoxicity,energy depletion and cell death) leading to brain damage and neonatal death.Under this background,the changing of biomarkers in different types of biological fluids able to be detected and prognosed HIBD.