1.Our Opinion on the Execution of the Pharmaceutical Patent Law in China
China Pharmacy 1991;0(04):-
In view of the fact that the Pharmaceutical Patent Law will be put into effect in China,the authors suggest that the development of new drugs in China should be relied mainly rather on creating than on copying. However,some of the effective drugs should be still modelled on foreign products. We should pay great attention to the research work on pharmaceutical preparations and the development of Chinese patent medicine, intermediates of preparation and reagents.
2.Report of a case with Potter's syndrome.
Chinese Journal of Pediatrics 2004;42(7):556-556
3.Positive effects of classification teaching method on motivation
Journal of Chongqing Medical University 2000;25(z1):116-117,120
It is generally agreed that motivation is one of the most important factors influencing the students success or failure in learning a language. Motivation, according to Harmer, is an internal drive that encourages the learner to pursue a course of action(1983: 3). Expressed more colloquially, when students perceive an attractive goal that they wish to achieve, they may do whatever is necessary to reach it. Then they are strongly motivated.This article aims at introducing the classification teaching method into English teaching. Studies suggest that classification teaching method has positive effects on motivation.
4.Detection of Chlamydia trachomatis DNA by gap ligase chain reaction (G-LCR)
Journal of Chongqing Medical University 1987;0(01):-
Objective:To develop a new nucleic amplication method for detection of Chlamydia trachomatis DNA by gap ligase chain reaction(G-LCR).Methods:A G-LCR DNA amplification assay that targeted the outer major membrane protein gene(omp1)of CT was established to detect CT infection.The sensitivity and specificity of a newly developed G-LCR test was examined by the use of highly purified elementary bodies (EBs).DNA fragments of different species and from other bacteria1 were detected with G-LCR and routine polymerase chain reaction (PCR).Results:Using G-LCR,DNA fragments of 54bp were amplified from five different species.The sensitivity could be improved to detect out 2 chlamydial elementary bodies.G-LCR detected ten-fold EBs than PCR.No signal was observed when C.pneumoniae and other bacteria were used as templates.Conclusion:G-LCR is sensitive,rapid and specific for detection of Chlamydia trachomatis.
5.Correlation Study on Self-identity,Personality and Mental Health of 188 Medical Freshmen
Hong-Hong XU ; Wei HONG ;
Chinese Mental Health Journal 2002;0(11):-
Objective:To explore the relations between freshmen's self-identity status,personality characteristics and mental health status.Methods:188 new students were asked to complete the questionnaires of mental health scale and personality scale from the China college students mental health evaluation system,and eollnge students self- identity status scale.Results:①the most status of identity is achievement(43.1%),then the identity diffusion (30.9%);②male students in compare with female,were more likely in achievement status(60.7?13.8/53.9?11.4,P0.406);③the achieve- ment status had obvious negative correlation with depression,dependency(r=-0.17~-0.24),the diffusion status had obvious positive correlation with depression,social-withdrawal,and impulsion(r=0.15~0.34);④active,ac- commodating,tough-minded personality characteristics had obviously negative correlation with mental symptoms(r= -0.16~-0.56).Conclusions:encourage college students to form the achievement ego-identity status,to be ac- tive,accommodating and tough-minded,will be helpful for their psychological health.
6.Extraction Technology Optimization of Guilong Cataplasm
China Pharmacist 2016;19(6):1190-1193
Objective:To optimize the extraction process of Guilong cataplasm .Methods:The yield of volatile oil was used as the index to optimize the volatile oil extraction technology by single factor tests. The yield of dry extract and the content of aconitine were used as the indices to optimize the water extraction technology by single factor tests and orthogonal test .Results:The optimal extraction conditions of volatile oil were as follows:the soaking time was 1h with 8-fold volume of water , and the extraction time was 6 hours.The optimal water extraction conditions were as follows:using 8-fold volume of water extracted for 3 times with 1 h for each time .Conclu-sion:The extraction process is simple , reasonable and reproducible ,which is suitable for the next research of Guilong cataplasm .
7.Research progress of mTOR signal pathway effect in cardiovascular system
Chinese Journal of cardiovascular Rehabilitation Medicine 2016;25(2):225-228
Mammalian target of rapamycin (mTOR)is an atypical serine/threonine protein kinase,which is a key protein kinase regulating cell growth,proliferation,translation,metabolism and autophagy.It's first known beca- nuse inhibited by rapamycin.Research indicated that mTOR plays a key regulating role in physiological and patho- logical process of cardiovascular system.The present article mainly reviewed research progress of mTOR signal path- way effect in cardiovascular system.
8.Dynamic monitoring of virus antibody during the establishment of SPF cynomolgus monkey population
Acta Laboratorium Animalis Scientia Sinica 2015;(6):573-577
Objective To investigate the positive and suspicious rates of BV, SRV, SIV and STLV-1 antibody of the cynomolgus monkeys introduced from Laos, dynamic monitoring of virus antibody during the establishment of SPF cyno-molgus monkey population, and then comparing the positive rate of virus antibody in the baby monkeys between the common with SPF populations.Methods Continuous monitoring four kinds of virus in the monkeys was carried out using special reagent kits and analyzed the data.Results In the introduced cynomolgus monkeys (n=1998), the positive rate of BV antibody was 52.35%, suspicious rate of BV antibody was 8.31%, and negative rate of BV antibody was only 39.34%, the positive rates of SRV and STLV-1 antibody were 7.45%and 8.56%, respectively, and positive or suspicious SIV anti-body in the cynomolgus monkeys was not detected.After screening and establishment of the SPF population, the positive rates of BV, SRV and STLV-1 antibody were 5.24%, 1.01%and 0.4%, respectively, in the year 2010.Then after five years of screening and elimination, by the end of 2014, the positive rates of BV, SRV and STLV-1 antibodies were 0.82%, 0.27%and 0.27%, respectively, and positive or suspicious SIV antibody in the cynomolgus monkeys was not de-tected.The BV antibody positive rate of the baby monkeys was 9.71%and the suspicious rate was 1.85%in the common population, but only 0.22%of the baby monkeys in the SPF population.Conclusions Continuous monitoring virus anti-bodies and eliminating positive and suspicious animals have important significance in the establishment of a SPF cynomolgus monkey population.
9.Introduction to nurse-staffing ladder and compensation system in NHS UK
Chinese Journal of Practical Nursing 2015;31(11):844-847
Objective To explore ladder and compensation system of nurse-staffing which is suitable for the situation of our country.Methods The ladder management and compensation system to nursestaffing of National Health Service (NHS) in UK were given detailed introduction and analysis through the official documents,references and personal study experiences,and summarize its scientific and referenced aspects.Results NHS has formed a set of mature competency-based ladder system,and linked the ladder system to compensation system,made a relative scientific performance appraisal system,realized the scientific competency matches the level,salary changes along with the level model.Conclusions It provides references and thinking to the in-depth reform of public hospitals in our country,and the development of high quality nursing service,as well as the implementation of nursing ladder management and compensation reform.
10.Effect of plastic surgery of double-palpebra with prolapse of lacrimal gland for blepharochalasis
Chinese Journal of Medical Aesthetics and Cosmetology 2014;20(3):186-189
Objective To investigate the clinical effect of plastic surgery of double-palpebra with reposition of lacrimal gland for blepharochalasis.Methods We operated on 10 cases (20 eyes) with dermatolysis palpebrarum which stopped attack and was static for more than one year.A double eyelid fold incision was made.Then redundant skin and sphincter palpebrarum as well as protrusion of intraorbital fat were removed.In the operation of dislocation of lacrmial gland we sewed up lacrmial gland in full thickness and fixed it to the periosteum of lacrmial fossa,and the levator muscle of upper eye lid aponeurosis prothesis or plication was choosed when the levator muscle of upper eye lid aponeurosis was broken or not.And for the shorted transverse diameter of coloboma of eye lid we sewed up the external palpebral ligament and fixed it to the periosteum of lateral orbital margin.Results All the 10 patients got satisfactory therapeutic effect,the cutis laxa had been amended obviously,the good upper double eyelid shape could be achieved,the reposition of lacrimal gland was finished,lapsus palpebrae superioris and shorted transverse diameter of coloboma of eye lid had been rectified satisfactorily.All cases we followed up for three monthes to one year,and dislocation of lacrmial gland had been amended in one case,others had been reposited well,without recurrence.Conclusions Blepharochalasis can be effectively treated by surgery,and it is convenient and effective to treat dislocation of lacrimal gland and blepharochalasis through a double eyelid fold incision.This multiple surgical treatment is not only a curative operation but also a cosmetic surgery.