Objective To explore the abdomen surgical incision infection risk factors,and to put forward prevention countermeasures.Methods 1 854 patients with abdominal surgery were selected as subjects.According to whether had surgical incision infection,they were divided into the infection group(76 cases)and the non -infection group(1 778 cases).Single factor analysis and Pearson correlation analysis were used to summarize abdominal surgical incision infection risk factors.Results Single factor analysis results showed that age,BMI,category of incision,operation timing,operation time,diabetes mellitus,drainage tube placement,summer were risk factors for abdominal surgery incision infection (t or χ2 =8.925,5.840,5.376,5.445,5.846,19.674,5.846,19.674,all P <0.05).Pearson correlation analysis showed that age,BMI,category of incision,operation timing,operation time,diabetes mellitus, drainage tube placement and summer surgery were risk factors for abdominal surgery incision infection (r =0.746, 0.689,0.746,0.689,0.691,0.548,0.760,0.548,all P <0.05).Conclusion Abdominal surgery incision infection is associated with many factors.It is necessary for all kinds of risk factors for targeted intervention to reduce incision infection rate.

Objective To explore the clinical results of cervical cerclage in the treatment of cervical incom -petence.Methods Selected 63 cases of cervical incompetence of pregnant women ,according to the patient′s treat-ment voluntarily that they were divided into the observation group (cervical cerclage +conservative therapy)40 cases and the control group (conservative therapy)23 cases,indicators of pregnancy outcomes were compared between the two groups .Results There were 3 cases the late abortions ,8 cases premature deliveries ,29 cases full-term pregnan-cies in the observation group ,there were 9 cases the late abortions ,9 cases premature deliveries ,5 cases full -term pregnancies in the control group,using test,there were the differences of the statistical significants between them (χ2 =16.623,P<0.01);In the observation group,there were 0 case the late abortions,6 cases premature deliveries, 20 cases full-term pregnancies at 10~16 gestational weeks among 20 cases,there were 9 cases the late abortions,9 cases premature deliveries ,5 cases full-term pregnancies at 17~25 gestational weeks among the other 20 cases,using test,there were the differences of the statistical significants between the two time stages (χ2 =10.882,P<0.05). Conclusion For pregnant women with cervical incompetence ,cervical cerclage was made early in the pregnancy ,can extend effectively the gestational times ,improve the fetal survival .

Objective: To investigate changes in T lymphocyte subsets and NK cells in patients with simple Graves' disease (GD) and Graves' disease combined with type 2 diabetes mellitus (GD/T2DM). Methods: Fifteen cases of GD/T2DM were selected from our hospital from November 2001 to November 2004. Before and after therapy thyroid function, thyroglobulin antibody (TGA), thyroid microsomal antibody (TMA) and blood glucose level were measured, and T lymphocyte subsets (CD3, CD4, CD8, CD4/CD8) and NK cells (CD56) were measured by immunofluorescence double labeling monoclonal antibody and flow cytometry, respectively. At the same time, comparison was made with simple GD (15 cases), T2DM (15 cases) and healthy control (20 cases). Results: Before therapy, CD4/CD8, CD4 and NK cells in GD/T2DM were less than normal, and there was no significant difference in comparison with simple GD (P<0.05). In T2DM group, only CD4/CD8 and CD4 were less than those of healthy controls (P<0.05). When thyroid function recovered after 1 to 3 months of methimazole treatment in both GD/T2DM and simple GD groups, various indexes recovered, which were more obvious in simple GD. Conclusion: Immune hypofunction of GD may be the key to the immune abnormality of GD/T2DM, which is more significant than that of simple GD or T2DM. The recovery of thyroid function and immune abnormality is not consistent, and the recovery of GD is more significant than that of GD/T2DM.

Objective: To investigate changes in T lymphocyte subsets and NK cells in patients with simple Graves' disease (GD) and Graves' disease combined with type 2 diabetes mellitus (GD/T2DM). Methods: Fifteen cases of GD/T2DM were selected from our hospital from November 2001 to November 2004. Before and after therapy thyroid function, thyroglobulin antibody (TGA), thyroid microsomal antibody (TMA) and blood glucose level were measured, and T lymphocyte subsets (CD3, CD4, CD8, CD4/CD8) and NK cells (CD56) were measured by immunofluorescence double labeling monoclonal antibody and flow cytometry, respectively. At the same time, comparison was made with simple GD (15 cases), T2DM (15 cases) and healthy control (20 cases). Results: Before therapy, CD4/CD8, CD4 and NK cells in GD/T2DM were less than normal, and there was no significant difference in comparison with simple GD (P<0.05). In T2DM group, only CD4/CD8 and CD4 were less than those of healthy controls (P<0.05). When thyroid function recovered after 1 to 3 months of methimazole treatment in both GD/T2DM and simple GD groups, various indexes recovered, which were more obvious in simple GD. Conclusion: Immune hypofunction of GD may be the key to the immune abnormality of GD/T2DM, which is more significant than that of simple GD or T2DM. The recovery of thyroid function and immune abnormality is not consistent, and the recovery of GD is more significant than that of GD/T2DM.

OBJECTIVETo study the effect of eight specifications of Cervi Cornu Pantotrichum on the osteoporosis of ovariectomized rats and grade the eight different specifications of Cervi Cornu Pantotrichum.

METHODTotally 100 SD female rats were divided randomly into 10 groups, namely the normal group, the model group and eight Cervi Cornu Pantotrichum groups of different specifications. Their bilateral ovaries were excised to reproduce the osteoporosis model. Meanwhile, the rats were given the eight different specifications of Cervi Cornu Pantotrichum for consecutively 12 weeks. Subsequently, the effects of the different specifications of Cervi Cornu Pantotrichum on bone mineral density and serum biochemical indicators of rats were observed. A clustering analysis was made for the eight specifications of Cervi Cornu Pantotrichum, with the serum content of ALP, BMP-2 and BGP as influencing factors.

RESULTAfter 12 weeks, the eight different specifications of Cervi Cornu Pantotrichum could significantly improve ALP, BMP-2, BGP in serum and bone mineral density of ovariectomized rats. And the cluster analysis showed similar results to the quality classification of traditional commercial herbs Cervi Cornu Pantotrichum.

CONCLUSIONDifferent specifications of Cervi Cornu Pantotrichum can antagonize the osteoporosis of ovariectomized rats, and their effects are related to the quality of commercial herbs.

Animals ; Bone Density ; drug effects ; Bone Morphogenetic Protein 2 ; genetics ; metabolism ; Deer ; Disease Models, Animal ; Female ; Horns ; chemistry ; Humans ; Osteoporosis, Postmenopausal ; drug therapy ; genetics ; metabolism ; physiopathology ; Ovariectomy ; Rats ; Rats, Sprague-Dawley

Angioplasty, Balloon, Coronary ; methods ; Humans ; Myocardial Infarction ; therapy ; Platelet Aggregation Inhibitors ; administration & dosage ; therapeutic use ; Tyrosine ; administration & dosage ; analogs & derivatives ; therapeutic use

Acute Coronary Syndrome ; therapy ; Humans

Objectives To investigate the outcomes of neonatals with abnormal hepatitis B virus (HBV) serological markers. Methods Twenty-eight neonatals who had abnormal HBV serological markers and whose mothers had positive HBsAg, HbeAg and HbcAb were studied. Among them, 21 neonatals who had positive HBsAg, HbeAg and HbcAb were included in vertical transmission group;7 neonatals who had positive HbeAg, HbcAb and negative HBsAg were included in suspicious group. The quantities of HBV serological markers were determined by time-resolved immunofluorometric assay (IFMA) and the level of HBV DNA were measured by fluorescence quantitative PCR (FQ-PCR). Results Serum HBeAg and HBsAg levels in suspi-cious group were lower than those in vertical transmission group (P<0.05). The results showed that HBeAg level (0.55 ± 0.19 PEIU/ml) three months after birth was lower than that (4.02 ± 2.00 PEIU/ml) 7 days after birth in suspicious group (P<0.05). Conclusions Early interference has positive effect in mothers and neonatls with abnormal HBV serological markers.

Perfusion computed tomography (CT) imaging is a kind of functional imaging technique to evaluate and determine the hepatic and portal blood flow noninvasively.It offers the significant clinical advantages in the early diagnosis,evaluation of treatment response,and prognosis assessment in chronic liver diseases.In this article,we reviewed the principle,scanning protocol,clinical applications,and advances in chronic liver diseases of hepatic perfusion CT imaging.

BACKGROUND:Despite regular mesh hydroxyapatite has certain biocompatibility and bone conductivity, it cannot be absorbed by human body after transplantation, and wil affect the growth and eruption of maxila and fangs when using for filing the injured alveolar cleft. OBJECTIVE: To compare the effect of conventional and new mesh hydroxyapatite composites in repair of alveolar cleft defects. METHODS: Totaly 46 patients with cleft lip and palate were randomly and evenly divided into test and control groups, and al were arranged according to cleft lip and palate sequence treatment. After nasal soft tissue defect repair, new mesh hydroxyapatite composite bone material (hydroxyapatite and bone morphogenetic protein compound). Conventional mesh hydroxyapatite material was adopted in the test and control groups, respectively. Within 6 months after the repair, the vertical distance from the newly formed bone tissue plane to the top of alveolar ridge was observed. The clinical repair effect was comprehensively evaluated from the aspects of complications, alveolar cleft shape and size, calus formation and material absorption. RESULTS AND CONCLUSION: At 2, 4, 8, 12 and 24 weeks, the vertical distance from the newly formed bone tissue plane to the top of alveolar ridge in the test group was higher than that in the control group (P < 0.05). The clinical repairing significant efficiency and total effective rate were al higher than those in the control group (P< 0.05). These results show that new mesh hydroxyapatite composite bone materials in the repair of alveolar cleft defects have good bone osteoinductivity and biocompatibility, rare complications and rapid calus formation.