1.Effects of Big Black Ant and Its Compound Preparations on the RNA and DNA Levels in Testes of Rats
Chinese Traditional and Herbal Drugs 1994;0(08):-
80 male Wistar mice were randomly divided into 8 groups. The effects of the big black Ant preparations (alias Xuanju ) obtained in different ways and their compound preparations in different dosages on the amount of RNA and DNA in the testes of mice were observed. After administration of the preparations for 21 days, the mice were decapitated and the testes were excised and weighed. The RNA and DNA in the testes were isolated andpurified with the method of SDS- phenol and their amounts were measured with UV-VIS spectrophotometry. The results showed that the mean testes weight in the experimental groups was significantly higher than that in the control group (P
2.The etiology of deep venous thrombosis in the lower extremities and its synthetic therapies
Journal of Interventional Radiology 2001;0(06):-
Deep venous thrombosis in the lower extremities is a very common disease clinically and can greatly affect people in their work and life without proper treatment promptly.The author reviewed the etiology,diagnosis,preventive measures and the synthetic therapies for dealing the deep venous thrombosis in the lower extremities,especially concerning the interventional radiology.
3.Impact study of basic medical research based on web of science
Chinese Journal of Medical Science Research Management 2015;28(1):106-111,115
Based on ESI web of science,the article analyzed papers published by three Medical Schools from 2001 to 2012 in terms of volume of publication,cited times,discipline distribution,au thors and cooperation,and determined each factor's impact on research output and performance.Sug gestions and advice were given to enhance the overall basic medical science research level.
4.Mandibular second molar with type 1-2 canal of mesial root:Report of one case
Journal of Practical Stomatology 2014;(5):725-726
The root canal system of mandibular second molar is complex.This article presents one case with type 1-2 mesial root canal of mandibular second molar.The canal was treated by warm gutta percha,and conformed by X-ray examination and dental operating microscopy.
5.Value of B-cell activating factor expression in the diagnosis and prognosis of children with idiopathic thrombocyto-penic purpura
Journal of Clinical Pediatrics 2014;(10):924-927
Objective To study the value of B-cell activating factor (BAFF) expression levels in the diagnosis and prog-nosis of children with idiopathic thrombocytopenic purpura. Methods Children with idiopathic thrombocytopenic purpura (ITP) admitted to our hospital from September 2011 to September 2013 were enrolled in observation group, and healthy check-up chil-dren during the same period were enrolled as controls. The serum levels of B-cell activating factor, platelet antibodies (PAIgG, PAIgM, PAIgA) and platelet count were detected, and curative effect in children with ITP was observed. Results The BAFF, PAIgG, PAIgM and PAIgA levels were higher and platelet count were less in both acute and chronic ITP children than those in normal controls. The difference was signiifcant (P<0.05). The results of linear regression analysis indicated that BAFF levels were positively correlated with PAIgG, PAIgM and PAIgA levels (β=1.87~2.25, P<0.05), and were negatively correlated with platelet count (β=-2.42, P<0.05). Meanwhile, BAFF levels were negatively correlated with curative effect in ITP children (β=-1.88, P<0.05). When the value of BAFF was 1.35, the sensitivity for predicting effective treatment was 0.84 and the speciifcity was 0.75. The area under the ROC curve was 0.85 (95%CI:0.73~0.98, P=0.000). Conclusions The serum BAFF expression was increased and closely related to the level of antiplatelet antibody, platelet count and treatment effect in ITP children, and therefore, was a good indicator for the diagnosis and prognosis of ITP.
6.Establishment of an in-vitro root canal-apical complex model
Chongqing Medicine 2014;(29):3907-3909
Objective To establish an in-vitro root canal-apical complex model for studying the mechanisms of the infected root canal to apical periodontitis and periapical biofilm .Methods Single rooted premolar extracted for orthodontic ,was sealed in sterile vial containing LB solid medium ,and the culture medium covered apical thirds .Totally 25 root canal-apical complex models were prepared .Five models were randomly selected for the bacteria detection in periapical by PCR at 1st day .The remained 20 models were randomly subjected to a control group(n=10) and experimental group(n=10) .Extracted teeth were opened in experimental group and control group with no treatment .All models were exposed in air .At 21st day ,bacteria were detected through PCR in root canal and apical;endotoxin content in apical was assayed by chromogenic end-point limulus test .Results In apical ,bacteria was not found in all groups ,but not for the experimental group .The mean endotoxin content was (8 .913 ± 0 .614)EU/mL in control group and (10 .525 ± 0 .981)EU/mL in experimental group .The endotoxin content was increased significantly in experimental group ,when compared with control group(P<0 .01) .Conclusion Root canal-apical complex was established in vitro through this method .Bac-teria was not easy to reach the apical when the infected root canal was not disturbed .Bacteria in the infected root canal caused apical periodontitis through the secretion of virulence factors such as endotoxin .
7.Transurethral ultrasonography in the diagnosis and staging of bladder tumor
Chinese Journal of Urology 2001;0(10):-
Objective To evaluate transurethral ultrasonic scanning in the diagnosis and staging of bladder tumor. Methods Form 1996 to 2000 transurethral ultrasonography(TUUS) was carried out for 70 cases of bladder cancer and the findings were compared with cystoscopy,transabdominal ultrasonography(TAUS),CT,MRI and pathological studies. Results The diagnosis rate of TUUS has been 99.1% being better than cystoscopy and TAUS.The accurate staging rate was 100.0% in stage T 1 tumors, 95.8% in stage T 2,82.4% in stage T 3 and 55.6% in stage T 4. Conclusions TUUS can clearly reveal the depth of tumor infiltration and therefore is an important method for the diagnosis and staging of early bladder tumor.
8.Retrospective Analysis of 2 Therapeutic Regimens for 56 Cases of Bone Metastasis of Cervical Cancer
China Pharmacy 2015;(26):3681-3683
OBJECTIVE:To evaluate therapuetic efficacy and toxic reaction of 2 therapuetic regimens for 56 cases of bone me-tastasis of cervical cancer. METHODS:56 cases of bone metastasis of cervical cancer with complete information were collected ret-rospectively and randomly divided into radiochemotherapy group(31 cases)and diphosphonate group(25 cases). Radiochemothera-py group was given radiotherapy,chemotherapy and diphosphonate;diphosphonate group was given palliative symptomatic treat-ment of diphosphonate;a treatment course lasted for 3-4 weeks,and both groups received 3 courses of treatment. Average survival time,survival quality and toxic reaction were comparison in 2 groups. RESULTS:After bone metastasis of cervical cancer,the av-erage survival time of radiochemotherapy group was 17 months (95%CI:9.1-24.9),and that of diphosphonate group was 19 months (95%CI:2.4-35.6);3 years later,the survival rate of radiochemotherapy group was 16.1%,and that of diphosphonate group was 16.0%,there was no statistical significance(P=0.820). To compared KPS after 3 treatment courses,the improvement rate of radiochemotherapy group(22.6%)was significantly lower than that of diphosphonate group(40.0%),with statistical signif-icance (χ2=4.36,P<0.05). Toxic reaction of radiochemotherapy group was more significant than that of diphosphonate group. CONCLUSIONS:Diphosphonate has little effect on survial quality and slight toxic reaction. It is worthy of spreading in some pa-tients with advanced,elderly and reccurred bone metastasis of cervical cancer.
9.Research on Thin Film type Hydrogen Sulfide Sensor Based on SnO2-CuO Nanofibers
Chinese Journal of Analytical Chemistry 2016;44(9):1315-1321
A SnO2-CuO composite nanofiber was prepared by the coaxial electrospinning method. A new thin-film-type hydrogen sulfide gas sensor was designed by coating SnO2-CuO composite nanofibers onto an alumina ceramic tube with Au electrodes by dip-coating method. The crystalline phase and microstructure of SnO2-CuO composite nanofibers were characterized using X-ray diffraction ( XRD ) and scanning electron microscope ( SEM) . The influence of chemical composition and thickness of sensitive film on the sensitive mechanism and electrochemical characteristic of SnO2-CuO nanofibers were analyzed. The characteristic tests of hydrogen sulfide sensor including sensitive performance, temperature, relative humidity, dynamic response, interference and stability were carried out by WS-30A type multifunction analyzer in gas sensor test system. The results demonstrated that, when the operating temperature was 25℃ and hydrogen sulfide gas concentration increased from 10 to 60 mg/L, the hydrogen sulfide sensor based on C50 composite nanofibers with 70 nm sensitive film thickness had the best linearity (92. 3%) and sensitivity (98. 2%). Besides, its highest response values and relatively humidity level were 1080 and 95%, respectively, and its dynamic response time and recover time were 4 s and 12 s, respectively. This sensor showed good anti-disturbance to the gases, such as CO, NO2 , SO2 , NH3 , CO2 , CH4 and H2 . The response value of the sensor was attenuated about 9. 2% when it was applied continually in the mine about 12 months, and its normal response time was 10. 9 months.
10.4 Cases of Disfunction of Blood Clotting Induced by Cefoperazoned/Sulbactam
China Pharmacy 2005;0(17):-
OBJECTIVE:To study conditions of disfunction of blood clotting induced by cefoperazoned/sulbactam.METHODS:Cases of disfunction of blood clotting induced by cefoperazoned/sulbactam in our hospital from Mar to May in2004were analyzed statistically.RESULTS:The chief clinical manifestation was alimentary tract hemorrhage,which may relate to the dosage and course of treatment of cefoperazoned/sulbactam.CONCLUSION:The application of cefoperazoned/sulbactam in senile patients should be more prudent.