1.The role of medical ethics archives in the medical ethics construction
Chinese Medical Ethics 1995;0(04):-
To perfect the medical ethics archives,we should stress the filling system of medical ethics evaluation,the detailed check and registration of medical staff's medical ethics condition.It could form the right think leading and normative professional criterion of medical staff,developing their work potential and decrease the conflict between doctors and patients.The main purpose and significance to establish and perfect the medical ethics archives is that it could bring the guidance,self-discipline,awards and punishments and regulation role in the medical ethics construction.
2.Reliability and Validity of the Chinese Version of the Test of Everyday Attention (TEA) among Normal Chinese People
Chinese Journal of Rehabilitation Theory and Practice 2011;17(6):515-518
Objective To explore the reliability and validity of the Chinese version of the Test of Everyday Attention (TEA) in normal Chinese people. Methods 117 normal volunteers (18~65 years old) were screened with the Montreal Cognition Assessment (MoCA), and the normal volunteers were administered to TEA (versions A), Trail Making Test B (TMT-B), Paced Auditory Serial Addition Task (PASAT), Stroop Color-Word Interference Test (SCWT), Continuous Performance Test (CPT). 20 normal volunteers were also given version B for testing of the test-retest reliability, time interval was 2 weeks between versions A and B. Results There was correlation between versions A and B in the major subtests (r>0.700, P<0.01) at a two-week interval. The varimax rotation principal-component analysis extracted 4 component factors, namely sustained attention, se lective attention, switching attention, and divided attention. The factors included various subtests of TEA and the other laboratory attentional test. Conclusion TEA has good reliability and validity.
3.Effects of Age, Education and Gender on the Chinese Version of the Test of Everyday Attention
Chinese Journal of Rehabilitation Theory and Practice 2013;19(10):945-948
Objective To test the impact of age, education and gender on the Chinese Version of the Test of Everyday Attention (TEA).Methods 117 normal volunteers were selected. They were grouped by age and education. After screening of Montreal Cognitive Assessment (MoCA), the volunteers were administered to the TEA (version A). Correlation analysis was performed between age and education with TEA. Comparisons between groups were tested in gender. Results There were significant correlations between most subtests with age except elevator counting, visual elevator counting (VE1) and lottery task. Education correlated with map search and elevator counting with reversal in the youth group. There were correlation between visual elevator (VE2) and telephone search while counting with education in the young and middle-aged group. Education related to map search, visual elevator (VE1, VE2), elevator counting with reversal, and telephone search in the middle-aged group. The subtests were not statistically different between different gender groups except telephone search. Conclusion Age and education had effect on TEA while Gender had no significant effect.
4.Theoretical of Attention and its Assessment(review)
Chinese Journal of Rehabilitation Theory and Practice 2009;15(10):956-959
This review summarized the important theory of attention and summed the attention assessment Methods and applications during the recent 50 years. In the future the field of neurological rehabilitation research in attention and attention assessment had been discussed.
5.Tetrandrine ameliorates cirrhosis and portal hypertension by inhibiting nitric oxide in cirrhotic rats.
Journal of Huazhong University of Science and Technology (Medical Sciences) 2004;24(4):385-8, 395
To examine the role and effect of nitric oxide synthase type II (NOS II) in cirrhotic rats, expression of NOS II mRNA was detected by real time RT-PCR. The enzymatic activity of nitric oxide synthase and the circulating levels of NO, systemic and portal hemodynamics and quantification of cirrhosis were measured. Chinese traditional medicine was used to treat cirrhotic rats and the effect of NO was evaluated. Double-blind method was used in experiment. Our results showed the concentration of NO and the enzymatic activity of NOS increased markedly at all stages of cirrhosis and iNOSmRNA was strongly expressed. Meanwhile, the portal-venous-pressure (PVP) and portal-venous-flow (PVF) were significantly increased. NO, NOS and iNOSmRNA were positively correlated to the degree of hepatic fibrosis. Tetrandrine significantly inhibited NO production and the expression of iNOSmRNA. Our results suggested that increased hepatic expression of NOS II is one of the important factors causing cirrhosis and portal hypertension. Tetrandrine can significantly ameliorate cirrhosis and portal hypertension.
6.Effects of epidural block anesthesia assisted sevoflurane for cesarean section on Apgar scores
Chinese Journal of General Practitioners 2013;12(4):294-295
To explore the feasibility of sevoflurane used in obstetric anesthesia and examine its effects on neonatal Apgar scores.A total of 60 cases of term primipara were assigned into epidural anesthesia assisted sevoflurane inhalation group (experimental group,n =30) and epidural anesthesia group (control group,n =30).In the experimental group after skin incision,the patients could not tolerate the anesthesia mask inhalation of sevoflurane.And the control group received no adjuvant drug.The maternal inhalation of sevoflurane to delivery of fetus after 1 min,5 min,10 min Apgar scores were analyzed.And the inhalation of sevoflurane to fetal childbirth duration were 4-10 min in two groups.The intergroup difference of newborn Apgar scores had no statistical significance (P > 0.05).Epidural anesthesia assisted sevoflurane inhalation for cesarean section had no significant effect on neonatal Apgar scores.
7.BRAFV600E gene mutation in papillary thyroid cancer
Xiaoping JIAO ; Shengying WANG
Journal of International Oncology 2012;39(3):206-208
The BRAFV600E mutation in papillary thyroid carcinoma is the most common genetic event,which is an invasive tumor clinical phenotype and a poor prognosis indicator.The BRAFV600E mutation detection has an important guiding significance for the differential diagnosis of malignant thyroid nodules on preoperative,guiding the surgical resection range of thyroid cancer,judging the patient(s) prognosis and guiding the subsequent treatment of postoperative.
8.Autophagy and cancer
Journal of International Oncology 2012;39(5):323-326
Autophagy is a dynamic process which subcellular membranes undergo morphological changes that lead to the degradation of cellular cytoplasmic organelles and macromolecules.It is regulated by themammalian target of rapamycin ( mTOR ) -dependent or -independent signaling pathways.It has been demonstrated that autophagy is induced or inhibited in various tumor cells,and it is closely related with cell survival and drug resistance.Because of the complex relationships with cell death,the roles of autophagy in cancer developnent,treatment,and drug-resistance are not the same,and thus controlling autophagy properly may become one of new means of cancer therapy.
9.The influence of osteoclasts during the repairs of tooth root in rats model of tooth resorption by intermittent injection of parathyroid hormone (PTH)
Chongqing Medicine 2013;(30):3644-3646
Objective To investigate the role of PT H (1-34 ) on the expression of receptor activator factor of NF-κB ligand (RANKL) in the induction of osteoclasts and its effect to osteoclasts on compression side during the repairs of tooth root in rats model of tooth resorption by intermittent injection of small dose of PTH (1-34) .Methods After the model of tooth resorption was established in rats 6-8 weeks in age ,63 male SD rats were divided in three groups .Rats in the control group were not given injec-tions for any drugs ;The negative control group were given injections for normal saline 6μg/kg subcutaneously every other day ;The experimental group were given injections for PTH (1-34) 6 μg/kg(PTH :1 μg/mL) subcutaneously every other day ;then rats in every group were killed on the day 0 ,7 ,10 ,14 ,17 ,21 ,25 .TRAP staining for counting TRAP-positive stained osteoclasts ,calculat-ing the mean ;Ligand RANKL immunohistochemistry and using image-pro-plus image analysis system to measure the average opti-cal density value of compression side .Results On the day of discontinuation ,the tooth resorption continued in each group ;the num-ber of osteoclasts between every two arrays there were no significant statistic differences (P>0 .05);RANKL immunohistochemis-try :Compared with control group and the negative control group ,the experimental group significantly increased in early stage ,and reduced in latest stage(P<0 .05) .Conclusion It indicated that intermittent injection of small dose PTH (1-34) did not cease the rats tooth resorption which occured during the period of tooth repair .
10.Research on color doppler ultrasound in the diagnosis of cesarean scar pregnancy
China Medical Equipment 2015;(12):143-145
Objective:To evaluate color doppler ultrasound diagnosis value of cesarean scar pregnancy.Methods: Using color doppler ultrasound probe belly and vaginal probe, faceted searches in patients with suspected scar pregnancy, observe suspicious gestational sac or clutter echo of the location, size, shape, and presence of complications, and radiography, video records, follow-up.Results: The abdominal and vaginal color to exceed cesarean scar pregnancy can make a definite diagnosis.Conclusion: Color doppler flow imaging (CDFI) in cesarean scar pregnancy has a characteristic ultrasonographic performance, ultrasound can accurately make a clear diagnosis. It is the first choice for clinical diagnosis.