1.Effects of budesonide suspension combined with terbutaline on the VAP and rehabilitation of thoracic surgery
Chinese Journal of Biochemical Pharmaceutics 2017;37(8):295-297
Objective To investigate the effect of budesonide suspension combined with terbutaline on the ventilator-associated pneumonia (VAP) and rehabilitation in patients undergoing thoracic surgery. Methods Fifty-five patients underwent thoracic surgery from June 2006 to January 2017 in our hospital. The patients were treated with budesonide suspension combined with terbutaline atomization solution for inhalation. Forty patients with thoracic surgery were selected as the control group. Comparison of the two groups after the blood gas indicators, the incidence of VAP, mechanical ventilation and hospital stay. Results There was no significant difference in white blood cells, neutrophils and CRP between the two groups.The oxygen saturation of the observation group was higher than that of the control group, the arterial oxygen partial pressure was higher than the control group, PaCO2 was lower than the control group, the difference was statistically significant (P<0.05). The VAP of the observation group was lower than that of the control group. The time of mechanical ventilation was shorter than that of the control group. The hospitalization time was shorter than that of the control group, the difference was statistically significant (P<0.05). Conclusion The combination of budesonide suspension and terbutaline atomization can improve the postoperative effect of thoracic surgery and reduce the incidence of postoperative VAP and promote the early rehabilitation of patients.
2.Surgical treatment of pancreatic cancer: present status and future
China Oncology 2009;19(8):570-573
The incidence of pancreatic cancer has steadily risen in the past decades. Radical resection is still the best option for treatment of pancreatic cancer. Great progress has been achieved in pancreatic surgery;the mortality and morbidity have decreased dramatically, but long term survival after resection is still dismal. Standard pancreaticoduodenectomy is recommended now for pancreatic head cancer. Extended lymphadenectomy could not improve the prognosis of pancreatic cancer patients. Total pancreatectomy is suitable for some IPMNs patients, rather than a routine for pancreatic cancer patients. The current status and future of surgical treatment for pancreatic cancer will be summarized here.
3.The effect of anterior fusion with the internal fixation in treatment of fracture-dislocation complicated with spinal cord injure
Chinese Journal of Primary Medicine and Pharmacy 2011;18(3):317-318
Objective To study the the effect and rate of complications of anterior fusion with the internal fixation in treatment of fracture-dislocation complicated with spinal cord injure. Methods 46 patients with fracturedislocation complicated with spinal cord injure were selected as group A 23 cases and group B 23 cases according to the methods of treatment,group A was treated with anterior fusion with the internal fixation,group B was treated with cervical posterior, then the total effective rate, surgical time, the rate of complications, ASIA scores and SF-36 scores before and after the treatment of the two groups were studied. Results The total effective rate of group A(91.3% )was higher than that (73.9%) of group B ( 17/23 ) ( x2 = 6. 38, P < 0. 05 ), surgical time ( 83.6 ± 23.5 ) min of group A was shorter than that of group B( 106.8 ±25. 1)min(t =5.37,P <0. 05) ,the rate[13.0% (3/23)]of complications of group A was lower than that of group B[26. 1% (6/23)] ,ASIA scores and SF-36 scores of group A after the treatment were better than those of group B(P <0. 05) ,there were significant differences. Conclusion The effect of anterior fusion with the internal fixation in treatment of fracture-dislocation complicated with spinal cord injure was better,and the the rate of complications was lower,and it was worthy of exploitation and promotion.
5.Short-term and Long-term Efficacy of Arthroscopic Debridement,Lateral Patellar Decompression,and Rehabilitation Therapy for Osteoarthritis of the Knee Joint
Yubin WANG ; Huifang WANG ; Wenhui ZHU
Chinese Journal of Minimally Invasive Surgery 2005;0(08):-
Objective To study the short-term efficacy of arthroscopic debridement,lateral patellar decompression,and rehabilitation thearpy for osteoarthritis of the knee joint,and to discuss the long-term outcomes of the treatments.Methods A total of 85 cases of osteoarthritis that were diagnosed according to the clinical diagnostic criteria of ACR were enrolled in this study.The patients were randomly divided into groups A(39 cases) and B(46 cases) to underwent arthroscopic debridement and arthroscopic debridement combined with lateral patellar decompression respectivley.All the operations were performed by a same surgeon.Postoperative rehabilitation thearpies were carried out by one group of therapist.The Lysholm,HSS,and PPI scores were evaluated before the operation,as well as patellar tilt test and patellar gliding test.The examinations were repeated in 3 and 6 months respectivley after the surgery.Results In group A,the scores of Lysholm,HSS,and PPI determined at month 3 were significantly higher than those before the operation,but not changed markedly at month 6.Whereas,in group B,the scores kept being increased after the surgery.At month 3,the scores in group A were higher than those in group B,however,at month 6,the Lysholm score in group B was higher than that in group A.Conclusions Arthroscopic debridement and postoperative rehabilitation are effective for imroving the symtoms and knee function in patients with osteoarthritis and limited ROM of the patella.Combining with lateral patellar decompression,the treatments can achieve better outcomes in 6 months.
6.Variation of plaque pH values after chewing xylitol gum
Yan SI ; Weijian WANG ; Wenhui WANG
Journal of Practical Stomatology 1995;0(04):-
0.05). When comparing the pH value of xylitol gum with the pH value of 0.1 kg/L sucrose solution, and comparing that with the sucrose gum, significant difference could be found between the changes of pH values at different time points (P
7.Estimation of the Power Spectrum of Heart Rate Variability Using Improved Welch Method to Analyze the Degree of Fatigue.
Wenhui XU ; Kaihua LIU ; Liting WANG
Journal of Biomedical Engineering 2016;33(1):67-77
Heart rate variability (HRV) is an important point to judge a person's state in modern medicine. This paper is aimed to research a person's fatigue level connected with vagal nerve based on the HRV using the improved Welch method. The process of this method is that it firstly uses a time window function on the signal to be processed, then sets the length of time according to the requirement, and finally makes frequency domain analysis. Compared with classical periodogram method, the variance and consistency of the present method have been improved. We can set time span freely using this method (at present, the time of international standard to measure HRV is 5 minutes). This paper analyses the HRV's characteristics of fatigue crowd based on the database provided by Physio-Net. We therefore draw the conclusion that the accuracy of Welch analyzing HRV combining with appropriate window function has been improved enormously, and when the person changes to fatigue, the vagal activity is diminished and sympathetic activity is raised.
Fatigue
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diagnosis
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Heart Rate
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Humans
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Regression Analysis
8.Determination of three components in Qingfei Huatan Pill by RP-HPLC
Yanqin ZHU ; Wenhui WANG ; Jun YANG
Chinese Traditional Patent Medicine 1992;0(11):-
AIM: To establish a RP-HPLC for determing the contents of naringin,hesperidin and baicalin in Qingfei Huatan Pill(Arisaema Cumbile,Fructus Aurantii,Pericarpium Citrireticulatae,Radix Scutellariae,etc.). METHODS: Naringin,hesperidin and baicalin were separated on a RP C_(18) column.Acetonitrile-water(20(∶)80)(adjusted to pH 2.2 with phosphoric acid) was used as the mobile phase.The detective wavelength was set at 280 nm. RESULTS: The linear ranges were in 1.24-6.2 ?g for naringin (r=(0.999 7))、1.1-5.5 ?g for hesperidin(r=(0.999 8)) and 2.32-11.6 ?g for baicalin(r=(0.999 9)).The recoveries were 99.29% with RSD of 1.78% for naringin、100.08% with RSD of 1.44% for hesperidin and 98.76% with RSD of 1.42% for baicalin respectively. CONCLUSION: The method is simple,accurate and reproducible.It may well be used for the quality control of this product.
9.Clinical Study of Shenqi Decoction in Treating Restenosis after Implantation of Stents in Patients with Coronary Artery Disease
Huayun ZHAO ; Wenhui WANG ; Jiangming LANG
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(02):-
Objective To observe the effect of Shenqi Decoction on inflammation and immune reaction, immune state, restenosis (RS) after implantation of stents in patients with coronary artery disease, and to investigate its mechanism. Methods Eighty-eight patients with coronary artery disease after implantation of stents were randomly divided into the treatment group (45 cases) and the control group (43 cases). The control group was treated with routine treatment, and the treatment group was treated with Shenqi Decoction additionally for six months. RS rate, the level of hs-CRP, the marker of activation of T lymphocytes (CD3+/HLA-DR+), sIL-2R and the scores of blood-stasis syndrome and deficiency of Qi syndrome were observed. Results The RS rate in the treatment group was lower than that in the control group (P
10.Regimens for inoperable locally advanced non-small cell lung cancer
Jiang XI ; Wenhui LI ; Li WANG
Journal of International Oncology 2014;41(4):279-282
Concurrent chemoradiotherapy is the optimal regimen for patients with inoperable locally advanced non-small cell lung cancer (LA-NSCLC).The application of new technologies such as positron emission tomography (PET)/CT and four dimensional CT (4D-CT) enhances the accuracy of radiotherapy and decreases adverse reaction.Induction chemotherapy and consolidation chemotherapy do not show benefit to survival.The targeted therapy and immunotherapy have the potential of improving the outcomes of inoperable LA-NSCLC.