1.Contrastive analysis of diagnostic value between multi-slice spiral CT and MR pulmonary artery angiographies in acute pulmonary embolism
China Medical Equipment 2017;14(6):61-64
Objective:To investigate the comparison of diagnostic value between multi-slice spiral CT (MSCT) and MR pulmonary angiographies in the diagnosis of acute pulmonary embolism.Methods: 86 patients with acute pulmonary embolism who underwent imaging examination were randomly divided into control group (43 cases) and observation group (43 cases) according to random number table method. The patients in the control group were analyzed with MSCT for enhanced scan under pulmonary angiography. The patients in the observation group were analyzed with MR for pulmonary artery imaging and pulmonary embolism. These results were compared depended on above data.Results: The differences of sensitivity and Youden index between control group and observation group were statistically significant (x2=10.052,x2=10.052,P<0.05), and the sensitivity of observation group was higher than that of control group, and both the diagnostic specificity of the two groups were 100%. For embolism of different part, the accuracy of observation group was higher than that of control group. And for the comparison of left multiple between the two groups, the difference were significant (x2=4.168,P<0.05). While for the comparisons of single, bilateral and multiple for right side, the differences between the two groups were no significant (x2=2.355, x2=0.917,x2=2.912,P>0.05). For the diagnosis of various indirect symptom, the accuracy of observation group was higher than control group. For the comparison of diagnostic accuracy of pulmonary segments infarct between the two groups, the difference of them was significant (x2=5.630,P<0.05). While the comparisons of pericardial effusion, pleural effusion and pulmonary artery hypertension, the differences of them between the two groups were no significant (x2=3.214,x2=3.733,x2=3.281;P>0.05).Conclusion: For patients with acute pulmonary embolism, the diagnosis by using MR imaging technology has series advantages, such as convenient operation and higher diagnostic accuracy, and it can accurately determine the severe degree of the disease.
2.Survey of Infective Disease in Community
Chinese Journal of Nosocomiology 2006;0(06):-
OBJECTIVE To investigate the status of community health services and offer a scientific basis for making a direction of community to control the infective disease.METHODS Totally 1503 outpatients were investigated retrospectively for infective diseases in community.RESULTS The average age of these patients was 65,the number of females was much more than males.The most frequently infective diseases were upper respiratory tract infection,bronchitis,periodontitis,etc.CONCLUSIONS It′s necessary to strengthen the community health service and to establish an effective system of health service.The patients must cultivate a health habit of life,they not only need in time diagnosis and treatment,but also enhance own knowledge about health and disease prevention.
3.Application of graphic method in external quality assessment of iodized salt
Chinese Journal of Endemiology 2015;34(10):773-776
Objective To evaluate the detection capability for salt iodine test by using graphic method,and to provide reliable detection data for prevention of iodine deficiency disorders.Methods The examination results of external quality assessment for disease control mechanism in Liaoning Province in 2013 were analyzed by using standard Z score and Youden plot.The level of reproduction and type of error were analyzed by Z score sequence diagram in order to find the outliers and results need to be reviewed by the Youden plot.Salt iodine was detected by the general test method in salt industry for determination of iodine (GB/T 13025.7-2012).Results According to single sample evaluation of the Z score,111 laboratories were qualified,the qualified rate was 97.4% (111/114).Three labs were not qualified,unqualified rate was 2.6% (3/114).According to double sample evaluation of the Z score,112 laboratories were qualified,the qualified rate was 98.2% (112/114).Two laboratories were not qualified,unqualified rate was 1.8% (2/114).According to the Youden plot,5 laboratories were possible outliers with results need to be reviewed.Conclusion Statistical graphic method has displayed the examination results directly,which is helpful in searching targeted improvements,and improving the detection capability.
4.Development of Human Lower Limb Dynamic Modeling and Simulation (review)
Chinese Journal of Rehabilitation Theory and Practice 2012;18(8):731-733
This paper mainly introduced the development of human lower limb dynamic modeling and simulation at home and abroad, and also proposed further promising development. Its modeling methods mainly included Newton-Euler method, Lagrangian method, Kane method, etc. Analysis methods primarily included multi-rigid-body dynamics analysis and finite element analysis. It is very important to make a more reasonable model and a practical simulation of human body which can help us design rehabilitation training equipment and intelligent prosthesis
5.The effect of levocarnitine and Vitamin-E on oxidative stress state and the function of endothelial cells in maintenance hemodialysts patients
Lihua WANG ; Jianhui ZHOU ; Xiaoling WANG
Clinical Medicine of China 2009;25(8):807-810
Objective To study the treatment effects of intravenous levocarnitine in combinaton wlth vitamin-E in the oxidative stress state,endothelial cell function and nutritional status of patients with maintenance hemodialvsis (MHD).Methods 83 patients with MHD were randomized to the control group (Group A),and three treatment groups:with levocarnitine (Group B),with Vitamin-E (Group C),with levocarnitine and Vitamin-E(Gmup D).Intravenous 1.0 g levocarnitine were administered to Group B,oral vitamin-E(200 mg,two times each day) to group C,and vitamin-E and levocarnitine were coadministratered to group D at the end of dialysis.The blood biochemical indicators of each group were measured respectively.At the same time,malondialdehyde(MDA),glutathione peroxidase (GSHPx) and nitricoxide (NO) expression were mesured.Results MDA of group A increased compared with pre-dialysis at the end of the 3rd month[(4.81±0.08)nmoL/L vs(4.62±0.06)nmol/L(P<0.05)].and GSHPx declined at the end of the 3rd month[(72.02±2.05)μmol/L vs(74.62±1.46)μmol/L(P<0.01)] Hemoglobin(Hb),and blood albumin (Alb) reduced without statistical significan (P>0.05);In group B and C.MDA declined more compared with Group A[(3.86±0.06)nmol/L,(3.81±0.19)nmol/L vs (4.81±0.08)nmoL/L,(P<0.01)],while the GSHPx and NO increased significantly[(92.11±1.62)μmol/L,(92.14±1.37)μmol/L vs(72.02±2.05)μmol/L;(64.24±1.72)μmol/L,(64.35±1.67)μmol/L vs (49.91±1.19)μmol/L(P<0.05)].In the 3rd month,Hb and Alb level rised obviously(P<0.05);Group D was better than Group B and C(P<0.01).Conclusions Levocamitine and Vitamin-E effectively improve oxidative stress and nutrition status and the function of endotllelial cells of the MHD patients.It probably slows atherosclerosis progress.Furthermore,the combined medication is better.
6.Application of health card service pattern in community health services
Jianhui WANG ; Peihua WANG ; Dong NI
Chinese Journal of Health Management 2009;3(4):194-197
Objective To discuss the effects of the health card-based services on community chronic disease management and the utility of community healthcare resources. Methods Follow-up investigation on utilization and satisfaction of card-based health services and coverage of chronic illness management was conducted among cardholder living at Dongcheng District of Beijing during July 1,2006 and December 31,2008. Results The rates of attendance and health education increased from 47.20% or 1.16% to 90.90% and 46.38% ,respectively. The coverage of high blood pressure management and standard hypertension management increased from 47.16% or 45.66% to 80.39% and 78.27%, respectively. The satisfaction of cardholder residents with community healthcare services was improved year by year. Conclusions The health card service pattern plays a significant role in improving chronic disease management,which results in more satisfaction with and utilization of healthcare resources in community.
7.Design of Balance Function Telerehabilitation System Based on C/S.
Xiulin XU ; Jiaojiao ZHANG ; Meijun AN ; Jianhui WANG
Journal of Biomedical Engineering 2015;32(2):363-372
This article shows a new design of telerehabilitation system for balance function assessment and training in our laboratory. The system is based on C/S network architecture, and realizes the telecommunication through socket network communication technology. It implements the teletransmission of training data and assessment report of sit-down and stand-up, online communication between doctors and patients, and doctors'management of patient information. This system realizes remote evaluation and telerehabilitation of patients, and brings great convenience for the patients.
Humans
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Physical Therapy Modalities
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Postural Balance
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Rehabilitation
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Telecommunications
8.Dynamic modeling and simulating of squatting-standing action of human body.
Jianhui WANG ; Xiulin XU ; Meijun AN ; Xiufang HU
Journal of Biomedical Engineering 2014;31(6):1250-1254
It is very difficult for stroke patients to complete the action of squatting-standing because their equilibrium function ability has been seriously declined. It was necessary, therefore, to do a deep research on the action of human squatting-standing and to set up an accurate model and simulation. In our modeling research, the movements of upper limbs and head was neglected, and a seven-segment model was developed to establish the coordinate system of human squatting-standing action. It calculated the knee joint moment and hip joint moment during squatting and standing by utilizing Lagrange method, and then simulated this mathematical model by utilizing Matlab. Geometric model of human squatting-standing was developed and simulated in ADAMS which proved that the established Lagrange model was reasonable. It would also provide significant theoretical references for further study and development of squatting-standing rehabilitation training equipment.
Biomechanical Phenomena
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Computer Simulation
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Hip Joint
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Humans
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Knee Joint
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Models, Theoretical
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Movement
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Posture
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Upper Extremity
9.Application of a Simple Method for Detection of Rubella Virus Genome by Loop-mediated Isothermal Amplification (LAMP)
Shuang WANG ; Jianhui ZHOU ; Xiang HOU
Chinese Journal of Vaccines and Immunization 2008;0(06):-
Objective To use a new simple Reverse Transcription Loop-mediated isothermal amplification(RTLAMP) method was applied to detect rubella virus nucleic acid and compared with Reverse TranscriptionPolymerase Chain Reaction (RT-PCR).Method Comparing the detection rate of the RT-LAMP method with that of RT-PCR for detecting rubella virus nucleic acid from rubella virus.Results The nucleic acid positive rates of all 11 strains of rubella virus were 100% by the two methods,the positive rate was 55%.Conclusion RT-LAMP is more simple and convenient than RT-PCR.
10.Expression and clinical significance of TIG1 gene in acute leukemia
Yan WANG ; Jianhui ZHOU ; Fengru LIN
Journal of Leukemia & Lymphoma 2012;21(4):197-198,202
Objective To investigate correlation between the expression of TIG1 and the prognostic significance in acute leukemia (AL).Methods The TIG1 expression level of 75 AL and 20 normal control (NC) were measured by Real-Time Quantitative PCR(RT-QT-PCR).Results TIG1 gene expressed at a higher level in NC(0.0609±0.0281 ) than that in de novo AL(0.0057±0.0035)(U=-6.321,P=0.000).The expression of TIG1 in complete remission patients(AL-CR)(0.0409±0.0244)were lower than that in NC too(U=-2.582,P=0.01).The expression of TIG1 in AL-CR patients (83.3 %) were higher than that in de novo AL (53.1%)(U=-6.366,P=0.000).In AL patients,the CR rate of high TIG1 level cases were higher than that in low level cases (x2=4.563,P=0.033).Conclusions Reduced expression of TIG1 may play an important role in the pathogenesis of AL.TIG1 can serve as a marker of poor prognosis in AL.