1.Survey of Infective Disease in Community
Chinese Journal of Nosocomiology 2006;0(06):-
OBJECTIVE To investigate the status of community health services and offer a scientific basis for making a direction of community to control the infective disease.METHODS Totally 1503 outpatients were investigated retrospectively for infective diseases in community.RESULTS The average age of these patients was 65,the number of females was much more than males.The most frequently infective diseases were upper respiratory tract infection,bronchitis,periodontitis,etc.CONCLUSIONS It′s necessary to strengthen the community health service and to establish an effective system of health service.The patients must cultivate a health habit of life,they not only need in time diagnosis and treatment,but also enhance own knowledge about health and disease prevention.
2.Application of graphic method in external quality assessment of iodized salt
Chinese Journal of Endemiology 2015;34(10):773-776
Objective To evaluate the detection capability for salt iodine test by using graphic method,and to provide reliable detection data for prevention of iodine deficiency disorders.Methods The examination results of external quality assessment for disease control mechanism in Liaoning Province in 2013 were analyzed by using standard Z score and Youden plot.The level of reproduction and type of error were analyzed by Z score sequence diagram in order to find the outliers and results need to be reviewed by the Youden plot.Salt iodine was detected by the general test method in salt industry for determination of iodine (GB/T 13025.7-2012).Results According to single sample evaluation of the Z score,111 laboratories were qualified,the qualified rate was 97.4% (111/114).Three labs were not qualified,unqualified rate was 2.6% (3/114).According to double sample evaluation of the Z score,112 laboratories were qualified,the qualified rate was 98.2% (112/114).Two laboratories were not qualified,unqualified rate was 1.8% (2/114).According to the Youden plot,5 laboratories were possible outliers with results need to be reviewed.Conclusion Statistical graphic method has displayed the examination results directly,which is helpful in searching targeted improvements,and improving the detection capability.
3.Contrastive analysis of diagnostic value between multi-slice spiral CT and MR pulmonary artery angiographies in acute pulmonary embolism
China Medical Equipment 2017;14(6):61-64
Objective:To investigate the comparison of diagnostic value between multi-slice spiral CT (MSCT) and MR pulmonary angiographies in the diagnosis of acute pulmonary embolism.Methods: 86 patients with acute pulmonary embolism who underwent imaging examination were randomly divided into control group (43 cases) and observation group (43 cases) according to random number table method. The patients in the control group were analyzed with MSCT for enhanced scan under pulmonary angiography. The patients in the observation group were analyzed with MR for pulmonary artery imaging and pulmonary embolism. These results were compared depended on above data.Results: The differences of sensitivity and Youden index between control group and observation group were statistically significant (x2=10.052,x2=10.052,P<0.05), and the sensitivity of observation group was higher than that of control group, and both the diagnostic specificity of the two groups were 100%. For embolism of different part, the accuracy of observation group was higher than that of control group. And for the comparison of left multiple between the two groups, the difference were significant (x2=4.168,P<0.05). While for the comparisons of single, bilateral and multiple for right side, the differences between the two groups were no significant (x2=2.355, x2=0.917,x2=2.912,P>0.05). For the diagnosis of various indirect symptom, the accuracy of observation group was higher than control group. For the comparison of diagnostic accuracy of pulmonary segments infarct between the two groups, the difference of them was significant (x2=5.630,P<0.05). While the comparisons of pericardial effusion, pleural effusion and pulmonary artery hypertension, the differences of them between the two groups were no significant (x2=3.214,x2=3.733,x2=3.281;P>0.05).Conclusion: For patients with acute pulmonary embolism, the diagnosis by using MR imaging technology has series advantages, such as convenient operation and higher diagnostic accuracy, and it can accurately determine the severe degree of the disease.
4.Development of Human Lower Limb Dynamic Modeling and Simulation (review)
Chinese Journal of Rehabilitation Theory and Practice 2012;18(8):731-733
This paper mainly introduced the development of human lower limb dynamic modeling and simulation at home and abroad, and also proposed further promising development. Its modeling methods mainly included Newton-Euler method, Lagrangian method, Kane method, etc. Analysis methods primarily included multi-rigid-body dynamics analysis and finite element analysis. It is very important to make a more reasonable model and a practical simulation of human body which can help us design rehabilitation training equipment and intelligent prosthesis
5.The effect of levocarnitine and Vitamin-E on oxidative stress state and the function of endothelial cells in maintenance hemodialysts patients
Lihua WANG ; Jianhui ZHOU ; Xiaoling WANG
Clinical Medicine of China 2009;25(8):807-810
Objective To study the treatment effects of intravenous levocarnitine in combinaton wlth vitamin-E in the oxidative stress state,endothelial cell function and nutritional status of patients with maintenance hemodialvsis (MHD).Methods 83 patients with MHD were randomized to the control group (Group A),and three treatment groups:with levocarnitine (Group B),with Vitamin-E (Group C),with levocarnitine and Vitamin-E(Gmup D).Intravenous 1.0 g levocarnitine were administered to Group B,oral vitamin-E(200 mg,two times each day) to group C,and vitamin-E and levocarnitine were coadministratered to group D at the end of dialysis.The blood biochemical indicators of each group were measured respectively.At the same time,malondialdehyde(MDA),glutathione peroxidase (GSHPx) and nitricoxide (NO) expression were mesured.Results MDA of group A increased compared with pre-dialysis at the end of the 3rd month[(4.81±0.08)nmoL/L vs(4.62±0.06)nmol/L(P<0.05)].and GSHPx declined at the end of the 3rd month[(72.02±2.05)μmol/L vs(74.62±1.46)μmol/L(P<0.01)] Hemoglobin(Hb),and blood albumin (Alb) reduced without statistical significan (P>0.05);In group B and C.MDA declined more compared with Group A[(3.86±0.06)nmol/L,(3.81±0.19)nmol/L vs (4.81±0.08)nmoL/L,(P<0.01)],while the GSHPx and NO increased significantly[(92.11±1.62)μmol/L,(92.14±1.37)μmol/L vs(72.02±2.05)μmol/L;(64.24±1.72)μmol/L,(64.35±1.67)μmol/L vs (49.91±1.19)μmol/L(P<0.05)].In the 3rd month,Hb and Alb level rised obviously(P<0.05);Group D was better than Group B and C(P<0.01).Conclusions Levocamitine and Vitamin-E effectively improve oxidative stress and nutrition status and the function of endotllelial cells of the MHD patients.It probably slows atherosclerosis progress.Furthermore,the combined medication is better.
6.Application of health card service pattern in community health services
Jianhui WANG ; Peihua WANG ; Dong NI
Chinese Journal of Health Management 2009;3(4):194-197
Objective To discuss the effects of the health card-based services on community chronic disease management and the utility of community healthcare resources. Methods Follow-up investigation on utilization and satisfaction of card-based health services and coverage of chronic illness management was conducted among cardholder living at Dongcheng District of Beijing during July 1,2006 and December 31,2008. Results The rates of attendance and health education increased from 47.20% or 1.16% to 90.90% and 46.38% ,respectively. The coverage of high blood pressure management and standard hypertension management increased from 47.16% or 45.66% to 80.39% and 78.27%, respectively. The satisfaction of cardholder residents with community healthcare services was improved year by year. Conclusions The health card service pattern plays a significant role in improving chronic disease management,which results in more satisfaction with and utilization of healthcare resources in community.
7.Second non-myeloablative allogeneic stem cell transplantation for malignant hematological diseases:a report of 6 cases
Jianhui QIAO ; Huisheng AI ; Danhong WANG
Chinese Journal of Organ Transplantation 1996;0(04):-
Objective To explore the clinical effects of second non-myeloablative stem cell transplantation (NAST). Methods Six cases of malignant hematological diseases receiving second NAST were retrospectively analyzed. Of them, 3 were suffered from transplant rejection after 1st NAST and the remaining 3 were stable mixed chimerism. Results Five of the patients achieved complete donor's chimerism and have been in disease-free-survival for 6~27 months. 1 GVHD occurred in only one of the 6 patients, and no transplant-related death happened. Conclusion Second NAST is effective for the treatment of patients with transplant rejection,and is also rational choice for those patients with refractory or relapse malignant hematological diseases.
8.Effects of water improvement on skeletal fluorosis in drinking-water-borne endemic fluorosis areas in Liaoning Province
Zhaoxia ZHENG ; Xiaowei FENG ; Jianhui WANG
Chinese Journal of Endemiology 2017;36(1):60-63
Objective To investigate the prevalence of adult skeletal fluorosis in drinking-water-borne endemic fluorosis areas in Liaoning Province and to observe the effects of preventive measures.Methods Three water-changed villages were selected from six drinking-water-borne endemic fluorosis counties,Faku County,Liaoyang County,Haicheng City,Linghai City,Fu Mongolia County,and Jianping County.Totally 18 diseased villages were selected as the investigation sites.The operating condition of the improvement projects was investigated and the fluoride level of drinking water was tested.People over the age of 25 and living in the local for more than 5 years in each survey site were selected and divided into five groups according to age groups of 25-,35-,45-,55-,and ≥65 years old.Ten people in each age group were selected,half male and half female,to examine skeletal fluorosis by X-ray.Clinical symptoms and bone change,including sclerotin,bones,and joints changes were also examined.Results The water fluorine values of two villages were 1.32 and 1.69 mg/L,more than the national standard (1.2 mg/L),while other 16 villages were between 0.5-1.0 mg/L.X-ray images were analyzed for diagnosis of skeletal fluorosis in 905 adults,and 46 cases were diagnosed as skeletal fluorosis in the 18 monitored villages.Xray detection rate was 5.08%,of which the X-ray detection rate of adult fluorosis in water fluoride qualified monitoring villages was 4.11% (33/803).The detection rate of adult skeletal fluorosis was 12.75% (13/102) in water fluoride unqualified monitoring villages.There was a significant difference of the total detection rates between the two groups of monitored villages (x2 =13.99,P < 0.05).Skeletal fluorosis was mainly happened in the age group over the age of 45,account for 89.13% (41/46).Peri-bone changes were observed in the 46 cases of patients with skeletal fluorosis.Conclusions The condition of skeletal fluorosis has been effectively alleviated after implementing the improvement measures.Prevention and treatment can effectively control the occurrence of fluorosis.
9.Diagnostic evaluation and treatment of central poststroke pain
Xueping WANG ; Jianhui LI ; Haijuan MI
International Journal of Cerebrovascular Diseases 2016;24(6):550-554
Central poststroke pain (CPSP) is a neuropathic pain syndrome that can occur after stroke.This syndrome is characterized by pain and sensory abnormalities in the body parts that correspond to the stroke lesion.CPSP occurs ia 1%-12% of stroke patients.A definite diagnosis of CPSP is difficult,mainly because of the variable clinical picture,the frequent concurrence of several pain types,and the lack of clear diagnostic criteria for CPSP.Management of the CPSP is challenging.This article reviews the diagnostic evaluation and treatment of CPSP.
10.Target-controlled Infusion of Midazolam on Conscious Sedation for Patients Undergoing Combined Spinal-epidural Anesthesia
Jianhui GAN ; Jie CHEN ; Xizhu WANG
China Pharmacy 2007;0(29):-
OBJECTIVE: To confirm the feasibility of target-controlled infusion of midazolam on conscious sedation for patients undergoing combined spinalepidural anesthesia and the needed target-controlled blood concentration.METHODS: Sixty patients undergoing combined spinal-epidural anesthesia were subjected to target-controlled infusion of midazolam.The level of sedation of midazolam was evaluated applying OAA/S score and bispectral index(BIS).The correlation between target-controlled blood concentration(Cp) and BIS was determined.The Cp,BIS,MAP,HR and SpO2 at different OAA/S were observed. RESULTS: When OAA/S score was 3,the required target-controlled blood concentration of midazolam was(122.8? 20.8) ng? mL-1 in midazolam sedation patients.There was a good correction between BIS and Cp,and BIS=— 3.28Cp+ 355.22(r=— 0.862 5,P