The results of the study on 33 cases of chronic hepatitis B treated with Zeffix (100mg = 1 tablet/day, in 2 fears continously) showed that the rate of patients who have normalized level of liver enzyme (AST and ALT) accounted for 66.6%. The sero conversion rate of HBeAg and negatiity of HBV-DNA was 48.5%. 45.5% of patients were recovered and the rate of recurrent was 9%. Zeffix has not side effects (some cases of fever, nausea, vomit of slight manifestation.
therapy ; Therapeutics ; drugs ; Hepatitis B, Chronic

Enzyme extended spectrum beta-lactamase (ESBL) was determined from 2396 strains of E.Coli and 802 strains of Klebsiella isolated from clinical specimens at 18 hospitals (9 in North, 5 in Central and 4 in South of Vietnam in 1999-2001 years period by the method of Double Discs. Results showed that 6.4-7.8% of E.Coli and 15.6-29.7% Klebsiella strains produced ESBL. These percentages varied according to the strains isolated from various specimens
Escherichia coli ; Klebsiella ; epidemiology

This retrospective study was aimed to assessing clinical, paraclinical symptoms of 340 patients between 16-45 years old, with Dengue haemorrhagic fever. Patients were divided into 2 groups with and without Dengue Shock Syndrome (DSS). The results showed that clinical symptoms including sudden high fever, headache, orbital pain, congested skin, petechie, and positive tourniquet test. Paraclinical symptoms included thrombocytopenia increased haematocrite, leukopenia, increased serum transaminases. This disease often occurred in October and November. DSS can occure at 4th to 7th day with symptoms vomiting, sudden subsided fever, cold clammy skin, pleural or pericardial effusion, ascites, rapid increased haematocrite, thrombocytopenia, leukopenia. Dengue haemorrhagic fever can be cured in short time with infusion of isotonic fluid and Ringer lactate fluid
Dengue ; Hemorrhagic Disease Virus, Rabbit ; Dengue Hemorrhagic Fever ; diagnosis

Background: "Bach thuan" is a hereditary remedy which was written by herbalist Cao Van Tan, who was from Luu Ve, Quang Xuong, Thanh Hoa. The remedy has been treated effectively many diseases including the diseases related to infection wounds. Purposes: 1. to evaluate the antibacterial effect on Staphylococcus aureus and Pseudomonas aerucinosa in experimental burned animals. 2. to find unwanted effect of the "Bach thuan" remedy on experimental burned animals. Method: identifying the sensitivity of Staphylococcus aureus and Pseudomonas aerucinosa to the remedy. Conclusion: the remedy of “Bach thuan” had antibacterial effect to both Staphylococcus aureus and Pseudomonas aerucinosa. The remedy had effect of antimicrophyte to Staphylococcus aureus and Pseudomonas aerucinosa (ATCC 12228). With a dose of 25 mg/ml, the remedy killed 62.44% of bacteria after 4 days, 99.38% after 8 days of treatment. With a dose of 100 mg/ml, the remedy did not cause side effects
Anti-Bacterial Agents ; Pharmaceutical Preparations ; Plants, medicinal ; Staphylococcus aureus ; Pseudomonas aeruginosa

From September 1994 to August 2000, there were 206 patients with abdominal-thoracic injuries who admitted the Popular Hospital. Among these, there were 22 patients (10.7%) included 20 males and 2 females had heart and major blood vessel injuries. Mean age of patients was 30 years. All of them were stabbed with knife. 2/22 patients had treated previously in the other hospital. 20 patients had the mean time from accident to admission was 1 hour and 14 minutes (ranged from 15 minutes to 3 hours). Among 12 deaths, 4 cases occurred before admission, 2 before surgical intervention, 5 during operation, and 1 in second day post-operation. So, there were only 11 patients underwent surgical treatment, included 2 patients with heart injuries and 9 with major blood vessel injuries. 10/11 patients gained good outcome after operation. 1 in 11 patients was dead from abdominal aortic injury.
Injuries ; surgery ; Thoracic Injuries ; Wounds and Injuries

In the experiment planning series according to the simplex method, the antibiotics producing ability of the Micromonospora M 108 strain has been studied. As result of this research programme the optimal coordination of selected parameters have been found and the antibiotics producing ability has been risen up significantly.
Anti-Bacterial Agents ; Pharmaceutical Preparations

Linear discriminant analysis method basing on genetic algorithms was used to find out the role of clinical symptoms for taking differential diagnosis between typhoid fever and scrub typhus. Clinical records of 526 patients suffering from one of those diseases were used as input data for algorithms. The results showed that the differential value of symptoms are as follows: roseola (4 points), infectious constitution (2 points), drum belly (2 points), ingestive disorder (1 points), decrease of white-blood cell count (1 point), congestion (-2 points), enlarge of lymph node (- 2 points), erythematous eruption (-3 points), eschar (-5 points). The diagnostic rule are a follows: total point >=3: typhoid fever, between 0 and 2 points: suggestion of typhoid fever, total point <=-3: scrub typhus, between o and -2 points: suggestion of scrub typhus. To re-test on 50 patients of those 526 patients randomly, the accuracy rate of this rule is at least 98%.
Typhoid Fever ; Scrub Typhus ; diagnosis ; Algorithms

Based on the results of 20 cases with mumps orchitis who were treated with Prednisolon (25-30 mgs per day in 5 days) or Triamcinolon (5-6 mgs per day in 5 days), the author showed that corticoids could either release fever and pain within 24 hours or 48 hours, or reduce the swelling of orches faster in comparison with the other group of patients. Nevertheless, corticoids could not prevent the orches shrinking
Orchitis ; Mumps ; Therapeutics ; Adrenal Cortex Hormones

Genomes of 24 human and avian H5N1 influenza viral strains in the Southern area of Vietnam during the 2004-2005 outbreaks were sequenced completely. All viruses containing multiple basic amino acids at the hemagglutinin cleavage site HA1-HA2 are associated with a highly pathogenic phenotype. A series of amino acid mutations located in NSl and PB2 proteins were associated with the possibility of efficient replication in mammalian tissue. The mutation in the receptor binding sites of HA that could affect binding process to human cells was found from isolates in 2004-2005 Avianflu outbreaks. All isolates are belonging to Z genotype. The findings indicated that H5Nl viruses in Vietnam have changed to be more infectious to human host in 2004-2005 Avianflu outbreaks.
Influenza A Virus, H5N1 Subtype ; Humans

The study was conducted on Six hundred and thirty eight Streptococcus pneumoniae strains, 357 Haemophilus influenzae strains and 1475 Escherichia coli strains, were isolated from naso-pharyngeal, and rectal swabs in healthy children under 5 year olds, and 147 Salmonella typhi strains and 133 Shigella flexneri strains were isolated in 2002. These strains were tested for antibiotic susceptibility. The results showed that benzyl-penicillin was susceptible to S. pneumoniae pathogenous strains in community. The third generation cephalosporines showed the highest susceptibility to H. influenzae pathogenous strains in community. Ceftazidime, cefuroxime acetil and ciprofloxacine are antibiotics with high susceptibility to E. coli pathogenous strains in community. Fluoroquinolones and 2nd and 3rd cephalosporines are susceptible to S. typhi strains with high level. The most susceptible antibiotic to S. flexneri strains was ciprofloxacine.
Bacteria ; Microbiology ; Anti-Bacterial Agents