A randomized controlled trial was carried out on two groups of patients who were received either Flagystatine (nystatin 1000000 UI/metronidazol 500 mg) or Neo Penotran (miconazol 100mg/metronidazol 500 mg), twice a day for 7 days. Gynecological and microbiological assessments were carried out before treatment and 14 days after the first visit. In Flagystatine and Neo Penotran groups, clinical cure rates were 42% and 77.9% respectively; microbiological cure rates were 68.2% and 72.1%. In Neo Penotran group, functional symptoms were reduced more than organic symptom (84.8% and 79.1%, respectively). This difference was not so remarkable in Flagystatine group (64.8% and 65.95, respectively). Side effects of Neo Penotran were insignificant. Neo Penotran therapy without supportive treatment had higher efficacy in vaginitis at dosage of two pill a day in 7 days. The drug showed effects in both of function symptoms and organic symptoms, in clinical and paraclinical
Vaginitis ; Therapeutics

The effect of Ha Noi College of Pharmacy producted CTK tablet containing 0.5g CTK mixed powder on bacterial utero-vaginitis was studied on 31 female married subjects aged 18-44. Chloramphenicol 0.25g tablet producted by Central pharmaceutical Factory N2 was used control. Results showed that CTK tablet manifests antibacterial effect compared with chloramphenicol in utero-vaginitis. Antibacterial effect is 65.4% by a dose of treatment (20 times of application of tablet). The effect of healing the lesion was manifested earlier than that of chateravaginitisull
Tablets ; Vaginitis ; Bacterial Infections

The study was conducted on the women without chronic internal disease who were examined and followed at the Institute of Mother and newborn protection between 6/1998 and 10/2000. Obstetric and gynecological history and risk factors of candidosis were investigated. The results found that candidosis was more likely to occur during pregnancy. The candidosis incidence of women who lived in inner city was higher than that of women who lived in suburb. Pre-intercourse hygiene and menstrual hygiene under water stream linked to reduce the risk. Intrauterine device (IUD) and oral contraceptives had not related to vaginal candidosis
Vaginitis ; Pregnant Women

The prevalence of Bacterial vaginitis in pregnant women was 7.8%. 42.6% women with Bacterial vaginitis are asymptomatic. Risks associated with Bacterial vaginitis include history of IUD use (OR: 3.41; 95% Cl: 1.65-6.99) and changing pads under three times a day (OR: 2.19; 95% Cl:1.07-4.45). Amoxicillin is effective for treatment of Bacterial vaginitis in pregnant women.
Vaginitis ; pregnant women

The study carries on 1209 female patients from 16 to 55 years old at dermatology of dermatological hospital. These patients were tested to diagnose infected Bacteria vaginosis (BV), in particular, they were candled directly under optical microscope with enlargement 1000X to discover BV. The results were the rate infectious BV is the highest at the age group 26 – 35 (2.58%), and the age group 35 – 45 (2.4%), the possitive rate of the age group 26 – 45 is 4.98%. The total of infected patients is 27/1209 patients (2.23%). The rate infected BV of this research is much less than some studies of European countries as Poland, Swede, Belgium, England...
Vaginitis ; Vulvitis ; Vaginosis, Bacterial

No abstract available.
Child* ; Humans ; Shigella* ; Vaginitis*

100 women being infected with candida fungus and having itching at lower genital tract have been treated: 50 with micostat 7 and 46 with Lomexin vaginal insertion. In the micostat 7 group, 68.5% had negative results after treatment compared with 65.2% treated with Lomexin. The results after 2 stages of treatment reach 77.8% with micostat 7 and 87% with Lomexin. There is no difference about treatment result between these two drugs. There are no side effects in the patients of the two groups. The results suggested that micostat 7 may be an acceptable treatment for candida vaginitis.
Vaginitis ; Candida ; therapeutics ; Pharmaceutical Preparations

Background: Vulvovaginal Candidiasis (VVC) is one of the frequent infections of the female genital tract and is the second most common cause of vaginal infections after bacterial vaginosis. According to the Centers for Disease Control and Prevention, azoles are the first‑line treatment for VVC. Among the azoles available in the Philippines, only miconazole and clotrimazole are recommended for both pregnant and non‑pregnant women. Objective: Compare the effect of miconazole versus clotrimazole in the treatment of vulvovaginal candidiasis among patients seen at the out‑patient department in a tertiary hospital Materials and Methods: This involved review of the records of patients diagnosed with VVC in a tertiary medical center from 2016 to 2020. All records of women, pregnant and non‑pregnant, wherein single‑dose 1200 mg miconazole or 6‑day 100 mg clotrimazole given vaginally were included Results: Eleven out of the 316 records (3.46%) remained symptomatic after treatment, about 18.1% (2/161) from those who used miconazole and 81.8% (9/155) from those treated with clotrimazole (p 0.027). In terms of failure rate, for miconazole it was 1.2% (2/161), whereas for clotrimazole it was 5.8% (9/155). None of the charts were found to have recorded adverse reaction to the given treatment Conclusion Single‑dose miconazole intravaginal regimen has a higher clinical cure rate than the 6‑day clotrimazole intravaginal treatment. Thereby, single‑dose intravaginal miconazole has the potential to improve patient compliance and treatment outcome at a lower cost
Clotrimazole ; Miconazole ; Vaginitis ; Candidiasis, Vulvovaginal

A randomized study was carried out in women of reproductive age (from 18 to 49 years old) with vaginitis, cervititis due to bacteria who were treated with CTK tablets at Health Centre of Tuong Duong district, Nghe An province. The result showed that: CTK had high effect in treatment vaginitis, cervititis due to bacteria. The antibacterial effect of CTK tablets was the same with chloramphenicol. Antibacterial ability was 38.7% after one treatment course. Result of clinical treatment of CTK was better than chloramphenicol, expressed in reducing leucorrhoea and healing the cervical lesion. There was no side effect from CTK
Vaginitis ; Uterine Cervical Diseases ; Therapeutics ; Bacteria

OBJECTIVE: The aim of this study was to analize the biologic and molecular genetic characteristics of Lactobacillus spp. isolated from vagina of Korean healthy women and to perform a pilot clinical study on the treatment of vaginitis using the best Lactobacillus strain KLB 46. METHODS: Vaginal specimens were obtained from 205 Korean women with healthy vaginal ecosystems. 155 lactobacillus strains were used for catalase test, cell surface hydrophobicity (CSH) test and antimicrobial activity test. Also we identified the species prevalence by PCR-RFLP analysis of 16S rDNA gene and performed the minimal inhibitory concentrationtest using14 antibiotics to determine their patterns of antibiotic susceptibility. A pilot clinical trial of 8 bacterial vaginosis, 1 trichomonas vaginitis and 6 atrophic vaginitis using Lactobacillus crispatus KLB 46 was done by vaginal instillation (10(10)-10(11) cells/mL). RESULTS: 155 lactobacilli strains were isolated and all isolates showed high CSH and 61% of the isolates had higher CSH. L. acidophilus and L. crispatus were the most prevalent species by PCR-RFLP analysis of their 16S rDNA gene. And PCR-RFLP analysis suggested that KLB 46 was L. crispatus. The clinical study showed that the vaginal epithelial adherence rate was high as 77% for bacterial vaginosis and 33.3% for atrophic vaginitis. CONCLUSION: The predominating lactobacilli were L. crispatus and L. acidophilus in Korean women's vaginas. Although further study would be needed, L. crispatus KLB 46 is a good candidate of suitable probiotics for bacterial vaginosis.
Administration, Intravaginal ; Anti-Bacterial Agents ; Atrophic Vaginitis ; Catalase ; DNA, Ribosomal ; Ecosystem ; Female ; Humans ; Hydrophobic and Hydrophilic Interactions ; Lactobacillus* ; Molecular Biology* ; Prevalence ; Probiotics ; Trichomonas Vaginitis ; Vagina* ; Vaginitis* ; Vaginosis, Bacterial