Background Abdominal ultrasonography assesses the size, echotexture, shape, contour and adjacent structures of pancreas. Goal The goal of our study is to determining ultrasonography criteria of acute and chronic pancreatitis and developing algorithm of differential diagnosis. Objectives 1. To determine ultrasonography criteria of acute and chronic pancreatitis 2. To develop algorithms of differential diagnosis of acute and chronic pancreatitis Material and Method During the study period, 81 patients with acute pancreatitis, 66 patients with chronic pancreatitis has examined byultrasonography in Reference centre on Diagnostic Imaging named after R. Purev state laureate, people’s physician,hoporary professor of the State III nd Central Hospital,AchtanClinicalHospi tal,Central Clinic of Ulaanbaatar railway and Hepatological clinic centre of traditional medicine Result 48 (59.3%±5.5) patients with acute pancreatitis had reported pancreatic swelling /Exudative pancreatitis/, 18 (22.2%±466) had acute hemorrhagic pancreatitis, 15 (18.5%±463) had necrotizing pancreatitis. Conclusions 1. Determined ultrasonographic criteria of acute and chronic pancreatitis 2. Acute and chronic pancreatitis has diagnosed by ultrasonographic criteria and developed differential diagnosis algorithm.

Introduction: the background and importance of present research work consists on demonstrating how the drug substance digestion changes depending from the media of fluid to be taken. Purpose: consists in comparative study of solution of the diclofenac sodium film coated tablets, produced in various countries, in different solvent media by the in vitro method. Materials and Methods: the solution research of each 50mg total 54 pieces of film coated diclofenac sodium, produced in three different factories such as A, B and C, was conducted in three different medias in juice (pH=3.8); distilled water (pH=6.7) and mineral water (pH=6). The solution was determined in centrifuge and measured 276 nm in spectrophotometer. Result: the solution of 50mg diclofenac sodium film coated tablet, produced in three different countries such as A,B and C: • The amount of drug substance released in the distilled water (pH=6.7) media has been counted in 15 minutes after begin of solution process the A factory-66%, the B factory-58% and the C factory-20%. At continuation of duration of solution had in 30 minutes the A factory-80%, the B factory-86%, the C factory-72%; in 45 minutes the A factory-82%; the B factory-88%; the C factory-66%; in 60 minutes the A factory-82%; the B factory-82%; the C factory-72% each respectively. • The amount of drug substance released in the juice (pH=3.8) media has been counted in 15 minutes after begin of solution process the A factory-50%, the B factory-42% and the C factory-60%. At continuation of duration of solution had in 30 minutes the A factory-82%, the B factory-40%, the C factory-72%; in 45 minutes the A factory-80%; the B factory-44%; the C factory-38%; in 60 minutes the A factory-56%; the B factory-66%; the C factory-58% each respectively. • The amount of drug substance released in the mineral water (pH=6) media has been counted in 15 minutes after begin of solution process the A factory-54%, the B factory-30% and the C factory-10%. At continuation of duration of solution had in 30 minutes the A factory-66%, the B factory-62%, the C factory-36%; in 45 minutes the A factory-82%; the B factory-82%; the C factory-38%; in 60 minutes the A factory-74%; the B factory-84%; the C factory-74% each respectively. Conclusion: from the above-mentioned experiment it is evident that the solution of the diclofenac sodium film coated tablet, produced in different countries, in different solvent media as distilled water, juice and mineral water is relatively different. It has showed how important is to take into account the auxiliary substance quality contained in current drug at choosing the fluid to be taken after the drug. Bibliography: - “Drug analysis” D. Dungerdorj, Z.Anuu 2012 - “Bioformation” A.I. Tikhonov, T.G. Yarnykh, I.A. Zupanets, O.S. Danikevich, E.E. Bogutskaya, N.V. Bezdetko, Yu.N. Azarenko 2003

BACKGROUND. Traditional medicine is the oldest form of health care in the world and is used in the prevention and treatment of physical and mental illnesses3. Traditional medicine is also variously known as complementary and alternative, or ethnic medicine, and it still plays a key role in many countries today11. Plant produces a wide variety of secondary metabolites which are used either directly as precursors or as lead compounds in the pharmaceutical industry. It is expected that plant extracts showing target sites other than those used by antibiotics will be active against drug resistant microbial pathogens7. Antibacterial activities of various extracts, including methanol, ethanol, butanol and ethyl acetate crude extracts from traditional Tiishal medicine and its medicinal plants ingredients were carried out. Staphylococcus aureus, Pseudomonas aeruginosa, Micrococcus luteus, Salmonella enterica. For this purpose extract of drug Tiishal were prepared and tested by “Disc Diffusion Method”. As a result of this study it was found that the extract of Tiishal generally revealed antimicrobial activity against both gram positive bacteria (Staphylococcus aureus, Pseudomonas aeruginosa, Micrococcus luteus) and gram-negative bacteria (Salmonella enterica). The to study found that antibacterial activity of the ethanol extracts of each 6 samples showed little inhibition on Sal. enterica. METHODS. Traditional medicine Tiishal was produced from the Manba Datsan clinic and training center for traditional Mongolian medicine. Tiishal medicine was prepared by the standard MNS 5585:2006, № 0333151207 Tiishal medicine instructional method. The main medicinal herbs of Tiishal include Juniperus pseudosabinaFisch., Gentiana barbata Froel., Cynomorium songaricum Rupr., Sophora alopecuroides L., and Tricholoma mongolicum Imai (1:1:1:1:1) ratio. The antimicrobial activity of the ethanol, methanol, butanol and ethyl acetate extracts was carried by disc diffusion method. RESULTS. A total 4 strains were used for the antibacterial activity test. The extracts of methanol, and ethanol of J. pseudosabina revealed the highest antibacterial activity against Bac. subtilis, Ps. aeruginosa, S. aureus, and S. enteric with the diameters of inhibition zones between 6.0 - 10.0 mm. СONCLUSION. “Tiishal”, ethanol and methanol extracts of 5 different plants showed relatively low inhibition of bacterial growth.

Background: Medical geography deals with the application of major concepts and theories derived from human and physical geography to issues of health and disease. Between1970-1980, Russian scientists were first figured landscape, geographical distribution of TBE in Mongolia. Since human cases of TBD were registered from 2005, around 2000 cases of TBD were registered. From 15% of diseases and 78% of fatal cases were tick-borne encephalitis. Therefore, were tried to create current geographical distribution of TBE in Mongolia and detect risk areas. Мaterials and Methods: 287 TBE cases data, information of TBE positive tick and human data were analyzed which registered in NCZD between 2005-2017. Arc GIS 9 were used for create map. Mongolian map was divided by 5 landscape range such as forest-taiga, forest-steppe, steppe, steppe-desert, gobi and high mountain. Result: In forest-taiga range, 57% of TBE cases and incidence was 9.51 per 10000 population. 56.4% of I.persulcatus tick, 1.9% of D.nuttalli tick were found and infection rate of tick was Ixodes persulcatus-6.97%, Dermacentor nuttalli-5.2%. Seroprevalence of TBE was 25±12.1 among population.
In forest-steppe range, 40% of TBE cases and incidence was 0.56 per 10000 population. 43.6% of I.persulcatus tick, 44.3% of D.nuttalli, 24.4% of D.silvarum tick tick were found and infection rate of tick was Ixodes persulcatus-3.08%, D.silvarum-1.56% and D.nuttalli-1.56%. Seroprevalence of TBE was 14.5±11 among population.
In steppe range, 0.7% of TBE cases and incidence was 0.12 per 10000 population. 62.2% of D.silvarum tick, 23.9% of D.nuttalli tick were found and infection rate of tick was D.nuttalli-2.81% and D.silvarum-1.2%. Seroprevalence of TBE was 16.3±6.5 among population.
In other range including steppe-desert, gobi and high mountain, 2.8% of TBE cases and incidence was 0.1-0.27 per 10000 population. 62.2% of D.silvarum tick, 47.6% of D.nuttalli tick were found and infection rate of tick was D.nuttalli-0.84%. Seroprevalence of TBE was 2.5-13.1 among population. Conclusion Natural foci of tick-borne encephalitis have been registered in all landscape ranges of Mongolia and higher risk area of those ranges were forest-taiga and forest-steppe. Dermacentor silvarum, Dermacentor nuttalli tick becoming dominant vector of TBE in steppe range.