Thyroid nodular lesions are the common clinical problem in the world. A variety of tests have been employed to separate benign from malignant thyroid nodules. These tests include isotope scanning and fine needle aspiration cytology (FNAC). Our research was based on the fact that the comparison of FNAC and thyroid isotope scan in thyroid nodule was not researched in Mongolia. Therefore, we want to evaluate the specimen adequacy of FNAC, and compare its result to thyroid isotope scanning in patients with thyroid nodule. The research was conducted on archive materials of FNAC and thyroid isotope scanning of patients with thyroid nodule who were treated in surgical department of The First Central Hospital from 2012 to 2015, and the statistic analyze was done by using SPSS 20 under the auspices of School of Pharmacy and Bio-Medicine,Department of pathology, Mongolian National University of Medical Sciences. We have collected the FNAC of 807 patients, including 34 patients (4.2%) were males and 773 patients (95.8%) were females. FNA cytology results were interpreted as benign in 495 cases (61.3%), follicular lesion of undetermined significance in 31 cases (3.8%), follicular neoplasm in 9 cases (1.1%) suspicious in 17 cases (2.1%), malignant in 3 cases (0.4%), and unsatisfactory in 252 cases (31%). We have got the result of thyroid isotope scanning of 43 (5.32%) patients out of 807 cases. On thyroid scan, 18 patients (41.9%) having cold nodule were labeled as suspicious for malignancy, 25 patients (58.1%) had hot nodule. The FNA diagnosis of 25 patients with a hot nodule following: 1 patient (4%) with neoplasm, 17 patients (68%) with benign results, 6 patients (24%) had non-diagnostic. The FNA diagnosis of 18 patients (41.9%) with cold nodule following: 1 patient (5.5%) with follicular lesion of undetermined significance, 10 patient (55.5%) with benign, 5 patient (27.7%) with non-diagnostic, 2 patient (11.1%) had malignant. The FNAC results were interpreted as benign in 495 cases (61.3%), malignant in 3 cases (0.4%), and unsatisfactory in 252 cases (31%). Two patients out of 18 patients with cold nodule diagnosed as malignancy by FNAC. The sensitivity and specificity of thyroid isotope scanning was 96% and 16.6%, respectively.

Introduction: It is necessary and right to study and analyze all aspects of drug materials now when number of mineral based drugs are reducing. Especially it is very important for further researches to properly establish names and number of raw materials for traditional drugs based on ancient scripts. Goal: To carry out comparative study on mineral based drugs numbers and their differences mentioned in Mongolian and Tibetan manuscripts about drug identification methods using ‘Four basics of medicine’ book and its interpretations as a source. Materials and Methods: The study was conducted using methods of ‘Comparing manuscript sources studies’, ‘Analyses and syntheses’ for determining numbers and described with ‘Hermeneutics’ methodology. The study was based on approved methodology and ethical review in December 2018. Results: As it was compiled from manuscripts number of drugs mentioned in Four basic roots of medicine was 57, Ancestors’ important teachings – 68, Blue binderya – 77, Golden descript – 87, Clear crystal beads about medicine – 134, White crystal mirror – 121, Beauty eyes décor – 96. It is seen that books written about mineral based drugs became more comprehensive compared with previous manuscripts and authors were trying to reflect their on drug identification methods and ideas. Conclusion
1. The same time it evidences that traditional medicine was enriched year by year with innovation and searches of every generation scientists.
2. In “The four basics of medicine” manuscript theoretical book they described 57 mineral based traditional drugs but in other studies that number increased to 121 which means in manuscripts like “Basics of magic” and “Basics of future” drugs used that time were described more comprehensive.