No abstract available.
Uterine Prolapse*

No abstract available.
Uterine Prolapse*

No abstract available.
Uterine Inversion*

No abstract available.
Uterine Prolapse*

No abstract available.
Uterine Prolapse*

No abstract available.
Uterine Prolapse*

Genetic mutations in endometrial cancer (EC) have been extensively studied in the Western population but not much in Asian cohorts. This study has demonstrated that PTEN and PIK3CA mutations are commonly found in EC among Malaysian women. Following RNA extraction from 20 cancerous and 18 non-cancerous tissues, the presence of mutations in 9 exons of PTEN and 3 exons of PIK3CA genes were detected using realtime PCR, accompanied by High Resolution Melt (HRM) analysis. Sequencing confirmed specificity of each PCR product. The mutations for both genes were detected in the samples with varying frequencies. Notably, all samples expressed mutation of PTEN at exon 7 but none in exon 4. Further analysis demonstrated that strong concurrent mutations occurred between exons 7 of PTEN with exon 20 region 1 of PIK3CA gene (90%). Our data showed mutations are present in EC and not the non-cancerous tissues. Larger samples are being collected to validate this observation.
Uterine Neoplasms

We report the case of a rare, benign mesenchymal tumour arising from the cervix. A 53-year-old post-menopausal woman presented with mass per vagina. Examination revealed stage 2 utero-vaginal prolapse and multiple elongated polyps seen at the cervix. She underwent local excision. Histopathological examination findings and the immunohistochemical studies were consistent with Angiomyofibroblastoma.
Uterine Prolapse

In this day and age, with the advancement of treatments and the strong campaign to discourage home deliveries, chronic uterine inversion is now considered an uncommon but life-threatening obstetric condition. In this report, we present a case of a 17-year-old primipara, who sought consultation due to prolonged and heavy vaginal bleeding. Upon speculum examination, a knob-like, fleshy, hyperemic, smooth mass, approximately 6 cm × 5 cm × 4 cm, was seen occupying the upper third of the vaginal canal. On internal examination, a globular mass was felt protruding through the cervix, which bleeds easily on manipulation. Uterine corpus was neither appreciated on both abdominal and rectovaginal examination. The patient was admitted and managed as a case of chronic uterine inversion, which was further confirmed by a sonogram. Successful repositioning of the uterus was achieved after trying different established techniques and procedures in the attempts at maneuvering the chronically inverted uterus.
Uterine Inversion

Herlyn Werner Wunderlich Syndrome is a rare congenital Mullerian anomaly that commonly presents with uterine didelphys, obstructed hemivagina and ipsilateral renal agenesis. Presented here is a rare variant with contralateral dysplastic kidney with ectopic ureteral insertion instead of renal agenesis. The patient initially presented as a case of recurrent pelvic inflammatory disease who eventually underwent excision of vaginal septum with drainage of pyocolpos. Postoperatively, the patient had urinary incontinence and was eventually referred to Urology for further surgical intervention. The wide range of symptomatology and the uncommon anatomic presentation of this case led to the delay in the diagnosis and the consequent gynecologic complications.
Uterine Anomalies