1. HISTORY OF WESTERN ANATOMY IN MONGOLIA
Mongolian Pharmacy and Pharmacology 2013;2(1):47-
In the History of Yuan Dynasty, the 81st chapter of scripture “…Khubilai Khaan was established the Medical school in May, second year of Jun Tung”. This is certifying that first confidential hospital was formed in 1261 of public reckoning. In 1280 Mongolian State 5th article of law /one of the codes of law for 13th century were the hospitals /Military/ approved by State law during the 10-13th century, which had their strong rules and regulations. Doctor Khusekhui, a Mongolian nationality was printed the three volumes of book, which titled “Brief Practical Guide to Healthy Diet” printed in 1330. Also there are high needs to search theoretic creature about Mongolian food. Starting since 17th century Mongolian doctors, scientists were started to establish flow of “Four Medical Tantras” and based on “Astanga Hrdayam Samhita” written by famous Doctor Bagbat from Indian Auyrved /1500-1600/, “The explanation of Quintessence of the Eight Branches” his explanatory literature by Chandranandan, was compiled by sage Doctor, Elder Utog Yondongombo /729-854/ and Younger Utog Uoyndongombo reviewed again “Four Medical Tantras” during XII century. Study of personal history and works of famous Mongolian doctors and scholars is a tool for drawing historical tree of the traditional medicine. Of particular importance is period between 17th and 19th century which is a golden period of traditional medicine development. In this research project we identified the details of personal history of some scholars who had great contribution into the development of traditional medicine including Zaya Pandit Namkhaijamts from Oirad (1559), Lama Gegeen Luvsandanzanjaltsan (1639-1704), Zaya Pandit Luvsanprinlei (1642-1715), Lord Gombojav from Uzemchin (1680-1750), Arya jonlon Pandit Agvaanluvsandanbiijantsan (1770- 1845), Sube hambo Ishbaljir (1704-1788), Tsahar gevsh Luvsanchultem (1740-1810), Mindol nomuun Khan (1789-1838), Toin Jambaldorj (1792-1855), Luvsanchoimbal (19th century), Jigmeddanzanjamts (19th century), Ishdanzanvaanjil (1852-1906), Agvaangenden (19th century), Yondon (19th century), Lunrig Dandar (1831-1920), Choijamts (1860-1928). In addition, we also made observations on their works from the perspectives of theory, methodology and philosophy. Comprehending a science in light of its own methodology is important because then it opens up for observations from the perspective of other sciences and methodologies as well as creates new ideas.
2.НАТРИ ХӨӨГЧ ПЕПТИД БА ЗҮРХНИЙ АРХАГ ДУТАГДЛЫН ЗАРИМ ЭРСДЭЛТ ХҮЧИН ЗҮЙЛСИЙН ХАМААРАЛ
Batdelger T ; Chingerel KH ; Tsolmon U ; Tungalag Sh ; Dulamkhand B
Innovation 2017;11(2):19-21
BACKGROUND. Heart failure is the leading cause of the death among non-communicable
diseases. Heart failure is a fatal disease that once its clinical symptoms appeared,
five years of survival rate is 50-75%. Chronic heart failures are the main risk factors arterial
hypertension, diabetes, obesity and dyslipidemia Thus, early diagnosis before its symptoms
are presented and treatment with close monitoring is the most rational and effective
approach for decreasing heart failure diseases and deaths caused by it.
OBJECTIVE. To determine the level of NT-pro BNP in people with high risk of chronic
heart failure and assess its results. METHODS. We conducted hospital-based descriptive
study at State Second Central Hospital and Bayanzurkh District Medical Center. Total of
100 participants aged from 35 to 64 who had no symptom of chronic heart failure however
with high risk were recruited in this study. Based on the document entitled “Heart
failure prevention 2008” of the American Heart Association, old age, arterial hypertension,
diabetes mellitus, heart attack and obesity were considered as higher risks of heart
failure. Risk factors of heart failure were estimated by questionnaire and physical examination.
The level of NT-pro BNP in plasma was determined using FIA8000 analyzer.
According to the guideline produced by the European Society of Cardiology in 2016,
result of the testing is considered “positive” when NT-pro BNP is higher than 125 pg/ml.
Risk factors of chronic heart failure were studied in comparison with two groups which
were NT-pro BNP positive and negative results and their statistically significant difference
were determined. RESULTS. Of 87 participants, 51 (51%) were female and 49(49%) were
male. Half of the participants (51%) were aged between 55-64. Arterial hypertension
was determined in 88% of the participant, 38% were overdose drink of alcohol, therefore
55% were 1,2,3 levels obesity and 36% were diabetic. When determining the NT-pro BNP
level, in 34 cases (34%) were positive. Hence, 31% of the people with arterial hypertension,
9% of the people overdose drink with alcohol, 20% of the people with obesity, 12%
of the people with diabetes showed positive results of NT-pro BNP. When studying the
risk factors of chronic heart failure of the compared two groups of NT-pro BNP positive
and negative results, statistically significant difference (p<0.05) was increased of the
with arterial hypertension and obesity. CONCLUSION. NT-pro BNP is the arterial hypertension
and obesity which is increasing for people compared to the other risking factors
3.THE RELATIONSHIP BETWEEN ATHEROGENIC INDEX OF PLASMA AND RISKS OF CARDIOVASCULAR DISEASE
Rinchyenkhand M ; Tungalag Sh ; Sarantsetseg S ; Odgerel N ; Burmaa B ; Tsolmon U
Innovation 2017;11(4):27-31
BACKGROUND: Cardiovascular diseases (CVDs) account for >17 million deaths globally each year and this figure is expected to grow to 23.6 million by 2030. According to the WHO report, one-third of ischemic heart disease is attributable to high cholesterol. There have been some claims that the atherogenic index of plasma (AIP), which is the logarithmic transformation of the just-mentioned ratio (TG/HDL-C), could be used as a significant predictor of atherosclerosis, and CVD as well. Thus, we aimed to study the relationship between AIP and cardiovascular risk factors.
METHODS: The cross-sectional hospital based study was conducted including 117 participants aged between 40-72 years old without cardiovascular symptoms were recruited from Second General Hospital. After filled consent form, participants’ habits of smoking, alcohol usage, obesity, arterial hypertension and sedentary lifestyle were assessed through a structured questionnaire and physical examination. By using fully automated open-system analyzer, determinations of total cholesterol, triglycerides, low-density lipoprotein (LDL-C), high-density lipoprotein (HDL-C) three times and glucose twice were performed simultaneously and then their averages were calculated. At least one abnormal lipid level was considered as “dyslipidemia”. The atherogenic index of plasma (AIP) was calculated as the logarithmically transformed ratio of molar concentrations of TG to HDL-C. Statistical analysis was performed using SPSS 22.
RESULTS: Of total 117 participants ranging 40-72 years old, 45.3% were male and 54.7% were female with mean age 53.6±0.79. Regarding cardiovascular risk factors, 63.8% were physically inactive, 32.48% were smokers, 47% were alcohol user, 48% were hypertensive, and 18.26% were diabetic. The mean values plus standard error of lipid components were 195.5±6.09 mg/dL in cholesterol, 181.25±27.36 mg/dL in triglycerides, 60.6±1.39 mg/dL in HDL-C, 138.5±3.74 mg/dL in LDL-C, 6.27±0.26 mmol/L in fasting glucose. The dyslipidemia was detected in 54.7% of total participants and mean level of AIP was 0.33±0.03 (min=-0.52; max=1.51). The mean levels of 10 year and lifetime risk were 6.25±0.63% (min=0.2; max=33.5) and 43±1.53% (min=7.5; max=69), respectively. AIP had weak correlations with gender, smoking, anti-hypertensive drug usage, aspirin usage, 10 year and lifetime risks of CVD, hypertension, fasting glucose, body mass index, and dyslipidemia (0.2