Introduction: Tuberculosis (TB) is a public health problem worldwide including Brunei Darussalam. Osteoarticular involvement is common. The purpose of this study was to review the demographics, clinical features and treatment outcome of patients with osteoarticular tuberculosis (OATB) in Brunei Darussalam. Material and Methods: Patients receiving treatment for OATB between 2003 and 2008 were identified from the National Tuberculosis Coordinating Centre (NTCC) registry. Data was recorded on pre-designed proforma. Results: Twenty-one patients (10 male: 11 female) were identified with a mean age of 49 years (range 19 to 75). Nineteen were Bruneian citizens. The most common presenting symptoms were pain at affected site (n = 15), focal neurological deficit and loss of appetite (n = 7). Two patients gave a positive family history of TB and three had radiological evidence of pulmonary TB. Radiograph of the involved part was positive in nine cases while advanced imaging studies (computed tomography scan and magnetic resonance imaging) were required in 15 instances. The results of positive confirmatory tests were obtained from: smear (n = 10), culture (n = 3) and biopsy (n = 8). In five cases treatment had to be started without any of the confirmatory tests. The spine was the most common site of involvement (n = 12) with five non-spinal and four cases with combined lesions. Surgical intervention was required in six cases. All patients completed the treatment successfully. Conclusions: OATB is not uncommon in Brunei Darussalam and can present diagnostic problems. A high index of suspicion, early confirmation of diagnosis and complete monitored treatment is necessary for successful management of these cases.
Epidemiology ; Tuberculosis, Osteoarticular ; Tuberculosis

No abstract available.
Child* ; Humans ; Joints* ; Tuberculosis, Osteoarticular*

Disseminated bone tuberculosis is a rare manifestation of skeletal tuberculosis in adults in which cystlike lesions occur in the axial skeleton, shoulder, and pelvic girdles. Varied nomenclature applied to the entity of multiple cystic bone lesions in bone tuberculosis have been described in the literature. We experienced 2 cases of disseminated bone tuberculosis in adult.
Adult ; Humans ; Shoulder ; Skeleton ; Tuberculosis ; Tuberculosis, Osteoarticular

A survey on adverse effect of NSAID in the gastrointestinal tract in Rheumatic Department of one hospital showed that: gastrointestinal complications of NSAID were common. 26.3% patients were 40-59 years old. 27% patients had the medical history with NSAID. 18.6% cases had gastric complication when combining NSAID (acid derivation) with corticoid
Anti-Inflammatory Agents, Non-Steroidal ; Tuberculosis, Osteoarticular

A case of disseminated bone tuberculosis was reported, observed in a 23 year old male who visited with chronic ulcer on the midportion of the left upper arm and painful, tender swelling at the proximal part of the left tibia. Brief review was done regarding its pathogenesis and controversy of its nomenclature.
Arm ; Humans ; Male ; Tibia ; Tuberculosis, Osteoarticular ; Ulcer

Extraosseous tuberculosis of the extremities is relatively rare even in the wide spread incidence of bone and joint tuberculosis. And few reports about extraosseous tuberculosis of the extremities have been published in the literatures. Eight cases of the extraosseous tuberculosis of the extremities were experienced at the Department of Orthopaedic Surgery, National Medical Center, from 1975 to Sep. 1979. Five out of 8 extraosseous tuberculosis were tenosynovitis and the others were bursitis in location. All cases were surgically excised and combined with antituberculous chemotherapy, and primarily cured.
Bursitis ; Drug Therapy ; Extremities ; Incidence ; Tenosynovitis ; Tuberculosis ; Tuberculosis, Osteoarticular

Osteoarticular tuberculosis is a rare condition and it makes up 1-3% of all cases of tuberculosis. It usually occurs at the vertebra and it is common knowledge that tuberculous osteomyelitis is very rare at the foot. The clinical symptoms are nonspecific, and it can also mimic a wide range of pathologies, so it takes a lot of time to diagnosis and treat this illness. When osteoarticular tuberculosis is diagnosed, it should be gone through side to side with thorough debridement and chemotherapy. The author has experience 2 case of tuberculous osteomyelitis, so I report here on the diagnosis and treatment of this illness.
Debridement ; Foot ; Hydrazines ; Osteomyelitis ; Spine ; Tarsal Bones ; Tuberculosis ; Tuberculosis, Osteoarticular

Professor SHAO Jing-ming's clinical experience of fire needling for bone-joint tuberculosis, tuberculous cervical lymphadenitis, ganglion cyst and thyrophyma is summarized. Professor SHAO used fire needling to treat bone-joint tuberculosis. The acupoints included ashi points and nearby acupoints, particularly local opposite acupoints (Neixiyan [EX-LE 4] and Dubi [ST 35], Yinlingquan [SP 9] and Yanglingquan [GB 34], Xuehai [SP 10] and Liangqiu [ST 34]), and for the patients with severe yin-cold syndrome, Yanghe decoction was additionally used. For tuberculous cervical lymphadenitis, fire needling was used at different stages. In the early stage, the nucleus was punctured with fire needling; in the middle stage, the pustule was punctured with fire needling combined with cupping; in the late stage, the fire needling was inserted into the fistula or sinus tract, and the surrounding granulation tissue was treated with horizontal penetrating needling. For ganglion cyst, fire needling combined with centro-square needling was applied. For thyrophyma, the surrounding needling with filiform was used; for simple thyroid mass and thyroid nodule, the surrounding needling with fire needling was used.
Acupuncture Points ; Acupuncture Therapy ; Ganglion Cysts ; Humans ; Lymphadenitis ; Tuberculosis, Osteoarticular

Tuberculosis is caused by bacteria belonging to the Mycobacterium tuberculosis complex. Tuberculosis usually affects lung, although in about one-third of cases other organs are involved. Most of M. tuberculosis are drug susceptible strains, so infected patients are curable in virtually all cases. If untreated, the disease may be fatal within 5 years in more than half of cases and can be transmitted to others. We experienced a case of bone tuberculosis which was diagnosed by AFB stain in bone marrow aspirated filter biopsy. The patient was diagnosed later as a disseminated tuberculosis in which M. tuberculosis involved lung, lumbar spines, bone and brain.
Bacteria ; Biopsy* ; Bone Marrow* ; Brain ; Humans ; Lung ; Mycobacterium tuberculosis ; Spine ; Tuberculosis ; Tuberculosis, Osteoarticular*

Elbow tuberculosis is a rare disease which accounts for 1-3% of all cases of osteoarticular tuberculosis. The diagnosis of tuberculous arthritis is very difficult in most clinical situations because of the insidious onset, indolent process, and mild and non-specific local or systemic symptoms. Thus, the confirmatory diagnosis and effective treatment for tuberculous arthritis are delayed until the disease progresses to an advanced stage in many clinical settings. Herein we report a case of septic arthritis of the elbow due to Mycobacterium tuberculosis as a result of misdiagnosis and delayed treatments.
Arthritis ; Arthritis, Infectious ; Diagnostic Errors ; Elbow ; Mycobacterium tuberculosis ; Rare Diseases ; Tuberculosis ; Tuberculosis, Osteoarticular