We traced the meridional connection between each of five parenchymal organs and Its corresponding hormoimmunological organs.
In consequence of this research, we alloted hormoimmunological organs to Rokubu-joi pulse diagnosis region (cf. Table) . Of course, this theoretical application must be proved by a precise ultrasonic pulsimeter. In this work we found that there is a new meridian line between light Shaku and mingm@ea70/@n (GV4) and moreover a new point, upper mingm@ea70/@n (of KISHI, FUJITA and MARUYAMA), which may be a reacting point to the adrenal gland.

Tsutomu KISHI found that in Rokubu-joi pulse diagnosis, the pulse of the sun and the kan does not change, either in the masculine or the feminine, and of a right hander or a left hander as well.
But the pulse of Shaku on the left hand or right hand changes inversely according to the masculine or the feminine, and the same in the left hander or the right hander.
This law is confirmed by objectifying ten constitutions of 69 nan and 75 nan of acupuncture medicine by means of ultrasonic-pulsimeter of six derivatives.
In a masculine right hander, given one point acupuncture into the right Shaku, develop nine meridian lines, which run from shoulder to back. The third meridian line, which consists of three meridian lines, on the radial side, converges at Sanjiasohu (B₂₂). From here develop two meridian lines; the one caudally runs through the side abdomen on the same side and reached Zhongwan (CV₁₂) and the other does Shímén (CV₅). The second meridian line, running in the center, reaches Mìn mén (GV₄). There are two new latent papules at the crossing point between this meridian and the first line of the two bladder meridians. The first point, cranially situated from Mìn mén (GV₄), is named Shang Mìn mén by R. FUJITA, T. KISHI and M. MARUYAMA, which is a reacting point of the adrenal gland. The second and one, caudally situated from Mìn mén (GV₄), is perhaps called Wai-mìn mén by Ken SAWADA.
Now the meridian crosses the governor vessel from Mìn mén, caudally running in the opposite side abdomen and reaches Qìhai (CV₆). Then the meridian once more crosses the conception vessel, and reached Qìxué (K₁₃) or Zifu of the same side. From here develop two meridian lines; the one runs to Fushè (SP₁₃) and the other arrives at Guanyuán (CV₄). The meridian line from Guanyuán (CV₄) caudally runs parallel to the conception vessel and reaches Huìyin (CV₁) after all.
The first meridian line on the ulnar side from Shaku which also consists of the three meridian lines, reaches Shang Mìn mén, then runs through the same side abdomen and reaches Qìhai (CV₆).
The meaning of Mìn mén (GV₄) is a gate for life. The source of life is Yin yuan and Yang yuan. Yin yuan is Qìxué (K₁₃), and Yang yuan is Huìyin (CV₁). Guanyuán (CV₄) is the gardstation leading to Qìhai (CV₆) and Huìyin (CV₁).
Now Shang Mìn mén is a reacting point to the adrenal gland, Qìxué (K₁₃) to ovarium and Huìyin (CV₁) to testicles gland. It is very interesting that the reacting points of these three organs closely combine each other with meridian lines, and that the chemical structures of the hormones which their corresponding organs secrete are intimately similar.
In a masculine right hander given one point acupuncture into the left Shaku, also develop nine meridian lines, which run from shoulder to back.
The first line of the inner side which consists of three meridian lines reached Shenshu (B₂₃), the second midst line, Pángguángshu (B₂₈) and the third lateral one, Zhìshì (B₅₂). From each of these three points through the side abdomen on the same side, develop two meridian lines, referring to each point, and three meridians converge on two points, i. e. Zhongjí (CV₃) and Huangshu (K₁₆).
The matters related to the main subject: …From the view of Kishi's meridian, the stomach meridian related to glandula salivales tripper energizen meridian to hypophyses hypothalamus, and gall bladder

OBJECTIVE: Diagnosis of sporadic cerebellar ataxia is a challenge for neurologists. A wide range of potential causes exist, including chronic alcohol use, multiple system atrophy of cerebellar type (MSA-C), and sporadic late cortical cerebellar atrophy. Recently, an autosomal-dominant spinocerebellar ataxia (SCA) mutation was identified in a cohort of patients with non-MSA-C sporadic cerebellar ataxia. The aim of this study is to genetically screen genes involved in SCA in a Japanese single-hospital cohort. METHODS: Over an 8-year period, 140 patients with cerebellar ataxia were observed. There were 109 patients with sporadic cerebellar ataxia (no family history for at least four generations, 73 patients with MSA-C, and 36 patients with non-MSA-C sporadic cerebellar ataxia) and 31 patients with familial cerebellar ataxia. We performed gene analysis comprising SCA1, 2, 3, 6, 7, 8, 12, 17, 31, and dentatorubro-pallidoluysian atrophy (DRPLA) in 28 of 31 non-MSA-C sporadic patients who requested the test. Familial patients served as a control. RESULTS: Gene abnormalities were found in 57% of non-MSA-C sporadic cerebellar ataxia cases. Among patients with sporadic cerebellar ataxia, abnormalities in SCA6 were the most common (36%), followed by abnormalities in SCA1 (7.1%), SCA2 (3.6%), SCA3 (3.6%), SCA8 (3.6%), and DRPLA (3.6%). In contrast, gene abnormalities were found in 75% of familial cerebellar ataxia cases, with abnormalities in SCA6 being the most common (29%). For sporadic versus familial cases for those with SCA6 abnormalities, the age of onset was older (69 years vs. 59 years, respectively), and CAG repeat length was shorter (23 vs. 25, respectively) in the former than in the latter (not statistically significant). CONCLUSION: Autosomal-dominant mutations in SCA genes, particularly in SCA6, are not rare in sporadic cerebellar ataxia. The reason for the frequency of mutations in SCA6 remains unclear; however, the reason may reflect a higher age at onset and variable penetrance of SCA6 mutations.
Age of Onset ; Asian Continental Ancestry Group* ; Atrophy ; Cerebellar Ataxia ; Cohort Studies* ; Diagnosis ; Family Characteristics ; Genetic Testing* ; Heredity ; Humans ; Multiple System Atrophy ; Penetrance ; Spinocerebellar Ataxias*