Aconitum navicular (Brϋhl) Stapf, a Himalayan endemic, is an endangered medicinal herb of the alpine region. A search was made under the Latin Name Aconitum navicular (Brϋhl) Stapf. to summarize the use of phytochemical and biological information on the use of ethnomedicine available for the species. The keyword “Aconitum navicular (brϋhl) Stapf.” was collected and compiled from the rankings of PubMed, Web of Science, Google Scholar and other scientific websites. Phytochemical analysis done so far has led to the isolation of 14 alkaloids, 3 flavonoid glycosides, and 4 phenolglycosides. Most commonly, aqueous extract of this plant has been used against various kinds of fever, bitter tonic and intoxicating liquors. In addition, Aconitum species contain the most diterpenoid alkaloids, and this compound is bioactive and somewhat toxic. Many studies have shown that diterpenoid alkaloids exhibit cytotoxic, antioxidant, antimicrobial, analgesic, and anti-inflammatory biological activities. We hope this information will be useful in future research and development of this valuable medicinal plant.

Abstract: CHUN-7 a Mongolian traditional recipe consisting of 7 medicinal plants is described in the scripture named “༆༆ །།གཡུ་ཐོག་པའི་མཛད་པའི་རིམས སྲུང་ཁྱུ་ལྔ་རྒྱམ་ཏོན་གསལ་བ །།”. The ingredients including Caowu (Radix Aconiti kusnezoffii, CW) and Glehniae Radix (GR) have the effects of suppressing pneumonia, viral pneumonia, relieving pain, stimulating the immune system and reducing fever. The present study was aimed to determine acute and chronic toxicity properties of traditional drug. Materials and methods: CHUN 7 traditional drug were prepared in the traditional medicine sector of the Drug research Institute of Monos group. All WISTAR rats were kept in the same feed, under 12 hours lighting and 12 hours darkness housing. The study of acute and chronic toxicity of CHUN-7 traditional drug was studied by using IP and oral administration were performed on ten WISTAR rats and continued for a total of 28 days with 102.9 mg / kg dose (calculated from human dose: 16.7 mg/kg) in accordance with the WHO General Guidelines for the Evaluation and Study of Traditional Medicine. Results: The result showed no structural changes in the internal organs according to tissue morphology when we administrated CHUN-7 traditional drug. Conclusion This study showed CHUN-7 traditional drug has no toxic effects to internal organs including liver, kidney, stomach, lungs and heart. Therefore, CHUN-7 traditional drug has potential to use orally without any toxicology.