1.Direct Medical Costs of Dengue Fever in Vietnam: A Retrospective Study in a Tertiary Hospital
Nhung Thi Tuyet VO ; Trang Ngo Diem PHAN ; Trung Quang VO
Malaysian Journal of Medical Sciences 2017;24(3):66-72
Background: In Vietnam, dengue fever is a major health concern, yet comprehensive
information on its economic costs is lacking. The present study investigated treatment costs
associated with dengue fever from the perspective of health care provision.
Methods: This retrospective study was conducted between January 2013 and December
2015 in Cu Chi General Hospital. The following dengue-related treatment costs were calculated:
hospitalisation, diagnosis, specialised services, drug usage and medical supplies. Average cost per
case and treatment cost across different age was calculated.
Results: In the study period, 1672 patients with dengue fever were hospitalised. The
average age was 24.98 (SD = 14.10) years, and 47.5% were males (795 patients). Across age groups,
the average cost per episode was USD 48.10 (SD = 3.22). The highest costs (USD 56.61, SD = 48.84)
were incurred in the adult age group (> 15 years), and the lowest costs (USD 30.10, SD = 17.27)
were incurred in the paediatric age group (< 15 years).
Conclusion: The direct medical costs of dengue-related hospitalisation place a severe
economic burden on patients and their families. The probable economic value of dengue
management in Vietnam is significant.
2.Atypical Toxocara canis-Induced Hepatic Visceral Larva Migrans: Diagnostic Challenges and Literature Review
Tien Manh HUYNH ; Khanh Quoc Le TRAN ; Trung Hoang DINH ; Man Minh VO ; Thong Quang PHAM ; Thong Duy VO
The Korean Journal of Gastroenterology 2024;83(6):247-252
Toxocariasis, a zoonotic infection transmitted by Toxocara canis (from dogs) and Toxocara cati (from cats) larvae, poses rare but severe risks to humans. We present a case of hepatic visceral larva migrans (VLM) caused by Toxocara canis in a 21-year-old male with a history of close contact with a pet dog. Initial symptoms and imaging findings mimicked a pyogenic liver abscess. The initial laboratory investigations revealed neutrophilia and elevated levels of IgE. Despite broad-spectrum antibiotics, persistent fever prompted further investigation. Subsequent serological testing for Toxocara antibodies and histopathological analysis of liver tissue demonstrating eosinophil infiltrates and Charcot-Leyden crystals led to a confirmed diagnosis of a liver abscess caused by Toxocara canis. Serological testing for Toxocara antibodies and histopathological analysis of liver tissue confirmed a Toxocara canis-induced liver abscess. Albendazole treatment yielded significant clinical improvement. This case highlights the necessity of considering toxocariasis in liver abscess differentials, particularly in high-seroprevalence regions like Vietnam. Relying solely on serological tests may be insufficient, emphasizing the need for corroborative evidence, including invasive procedures like liver biopsy, for accurate hepatic toxocariasis diagnosis.