1.Atypical Toxocara canis-Induced Hepatic Visceral Larva Migrans: Diagnostic Challenges and Literature Review
Tien Manh HUYNH ; Khanh Quoc Le TRAN ; Trung Hoang DINH ; Man Minh VO ; Thong Quang PHAM ; Thong Duy VO
The Korean Journal of Gastroenterology 2024;83(6):247-252
Toxocariasis, a zoonotic infection transmitted by Toxocara canis (from dogs) and Toxocara cati (from cats) larvae, poses rare but severe risks to humans. We present a case of hepatic visceral larva migrans (VLM) caused by Toxocara canis in a 21-year-old male with a history of close contact with a pet dog. Initial symptoms and imaging findings mimicked a pyogenic liver abscess. The initial laboratory investigations revealed neutrophilia and elevated levels of IgE. Despite broad-spectrum antibiotics, persistent fever prompted further investigation. Subsequent serological testing for Toxocara antibodies and histopathological analysis of liver tissue demonstrating eosinophil infiltrates and Charcot-Leyden crystals led to a confirmed diagnosis of a liver abscess caused by Toxocara canis. Serological testing for Toxocara antibodies and histopathological analysis of liver tissue confirmed a Toxocara canis-induced liver abscess. Albendazole treatment yielded significant clinical improvement. This case highlights the necessity of considering toxocariasis in liver abscess differentials, particularly in high-seroprevalence regions like Vietnam. Relying solely on serological tests may be insufficient, emphasizing the need for corroborative evidence, including invasive procedures like liver biopsy, for accurate hepatic toxocariasis diagnosis.
2.Direct Medical Costs of Dengue Fever in Vietnam: A Retrospective Study in a Tertiary Hospital
Nhung Thi Tuyet VO ; Trang Ngo Diem PHAN ; Trung Quang VO
Malaysian Journal of Medical Sciences 2017;24(3):66-72
Background: In Vietnam, dengue fever is a major health concern, yet comprehensive
information on its economic costs is lacking. The present study investigated treatment costs
associated with dengue fever from the perspective of health care provision.
Methods: This retrospective study was conducted between January 2013 and December
2015 in Cu Chi General Hospital. The following dengue-related treatment costs were calculated:
hospitalisation, diagnosis, specialised services, drug usage and medical supplies. Average cost per
case and treatment cost across different age was calculated.
Results: In the study period, 1672 patients with dengue fever were hospitalised. The
average age was 24.98 (SD = 14.10) years, and 47.5% were males (795 patients). Across age groups,
the average cost per episode was USD 48.10 (SD = 3.22). The highest costs (USD 56.61, SD = 48.84)
were incurred in the adult age group (> 15 years), and the lowest costs (USD 30.10, SD = 17.27)
were incurred in the paediatric age group (< 15 years).
Conclusion: The direct medical costs of dengue-related hospitalisation place a severe
economic burden on patients and their families. The probable economic value of dengue
management in Vietnam is significant.

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