1.Characteristics of cranial trauma treatment of under 16 years old children in Binh Dinh General Hospital
Ty Pham ; Truc The Nguyen ; Ut That Quynh Ton ; Vu Trong Le
Journal of Surgery 2007;57(1):84-88
Background: Cranial trauma is a major cause of death among types of trauma. So far, although pediatric cranial trauma can leave more severe consequences, it has not still been adequate attended.\r\n', u'Objectives: To study clinical characteristics and cranial trauma treatment of under 16 years old children in Binh Dinh General Hospital. Subjects and method: A retrospective study was conducted on 256 under 16 year old patients with cranial trauma (180 males, 76 female) in Binh Dinh General Hospital from January, 2005 to September, 2005. Results:Cranial trauma in children was common seen in male/female ratio as 70.31/29.69. Common aged between 3-16 years old (89%). Main cause of it was traffic accident (64.5%). 100% of patients admitted to hospital with a Glasgow score 11 points. In those aged 3-16 years old, 14.03% of them with score of Glasgow coma scale \ufffd?2 points. Cranial CT scans: 78 patients, Cranial X-rays: 122 patients. Surgical rate 10.6%. Mean surgical days was 5.12\xb13.80 days. Complication rate was 33.2%. Non-operative mortality was 1.56%. Conclusion: Cranial trauma was common seen in those aged 3-16 years old, in male more than female. According to Glasgow outcome scale, good recovery rate achieved 65.23%. \r\n', u'
Craniocerebral Trauma/ diagnosis
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surgery
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therapy
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Child
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Child
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Preschool
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2.Laparoscopic Hartmann reversal: experiences from a developing country
Dung Anh NGUYEN ; Tuong-Anh MAI-PHAN ; Truc Thanh THAI ; Hai Van NGUYEN
Annals of Coloproctology 2022;38(4):297-300
Purpose:
Laparoscopic surgery is considered a promising approach for Hartmann reversal but is also a complicated major surgical procedure. We conducted a retrospective analysis at a city hospital in Vietnam to evaluate the treatment technique and outcomes of laparoscopic Hartmann reversal (LHR).
Methods:
A colorectal surgery database in 5 years between 2015 and 2019 (1,175 cases in total) was retrieved to collect 35 consecutive patients undergoing LHR.
Results:
The patients had a median age of 61 years old. The median operative time was 185 minutes. All the procedures were first attempted laparoscopically with a conversion rate of 20.0% (7 of 35 cases). There was no intraoperative complication. Postoperative mortality and morbidity were 0 and 11.4% (2 medical, 1 deep surgical site infection, and 1 anastomotic leak required reoperation) respectively. The median time to first bowel activity was 2.8 days and median length of hospital stay was 8 days.
Conclusion
When performed by skilled surgeons, LHR is a feasible and safe operation with acceptable morbidity rate.
3.Histopathology and ultrastructural findings of pediatric sialolithiasis:a brief communication
Kezia Rachellea MUSTAKIM ; Truc Thi Hoang NGUYEN ; Mi Young EO ; Soung Min KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2022;48(2):125-129
Sialolithiasis is a condition in which the salivary gland excretory duct is obstructed due to the formation of calcareous deposits and is uncommon in children compared to adults. The treatment modalities range from a conservative approach involving hydration to a surgical approach. Though several studies have analyzed the sialolith micromorphology structures, studies on pediatric sialoliths remain scarce. This brief communication aims to describe the sialolith micromorphology to understand the mechanism of mineralization and growth of pediatric sialoliths. A 6-year-old Korean female presented with swelling under her tongue. The intraoral examination revealed a painless yellowish hard mass beneath the tongue near the Wharton’s duct which was suspected as a sialolith. After receiving the informed consent, the sialolithotomy was performed under local anesthesia. The obtained stone was analyzed through histopathology and transmission electron microscope examinations to understand the mechanism of mineralization and growth of pediatric sialolith. The micromorphology and growth processes of pediatric sialolith remain undescribed. More comprehensive microscopic studies are needed regarding their distinctive characteristics. By expanding knowledge about sialoliths micromorphology, development of new preventive, diagnostic and patient-tailored treatment methods of pediatric sialolithiasis will be enhanced.
4.Assessment of In vitro Antioxidant, Antidiabetic and Cytotoxic Activities of Sphaeranthus africanus Extracts
Tran Thi HUYEN ; Julien DUJARDIN ; Nguyen Thi THU HUONG ; Chung Thi MY DUYEN ; Nguyen Hoang MINH ; Ha Quang THANH ; Dao Tran MONG ; Ly Hai TRIEU ; Nguyen Mai TRUC TIEN ; Mai Thanh CHUNG ; Nguyen Nhat MINH ; Nguyen Thi NGOC DAN ; Huynh LOI
Natural Product Sciences 2023;29(2):98-103
Sphaeranthus africanus is commonly used as a traditional remedy for sore throats and pain treatment in Vietnam. The aerial parts have been studied for its anti-inflammatory and anti-proliferative properties. However, the antioxidant and antidiabetic potential of the plant has not been explored. In this work, hydrophilic extracts of the plant's aerial parts were prepared in order to investigate its antioxidant and anti-diabetic properties. Also, the cytotoxicity of the root was evaluated and compared to that of the aerial parts. All of the extracts inhibited lipid peroxidation with IC 50 values ranging from 2.05 to 3.56 µg/mL, indicating substantial antioxidant activity. At an IC 50 value of 4.80 μg/mL, the 50% ethanol extract exhibited the most potent inhibition of α-glucosidase. The cytotoxic activity of root extracts is 2 to 5-fold less than that of the aerial parts. Nevertheless, dichloromethane and ethyl acetate extracts of the root demonstrated a selective effect on leukemia cells, with no harm towards the normal HEK-293 cell line. This work provides a scientific support for the antioxidant and antidiabetic activity of the plant. Hence, it may find a promising material for the development of novel antioxidant and antidiabetic agents. More research can be conducted on the phytochemistry and anticancer activities of the plant’s root.
5.7-mm-long dental implants: retrospective clinical outcomes in medically compromised patients
Truc Thi Hoang NGUYEN ; Mi Young EO ; Yun Ju CHO ; Hoon MYOUNG ; Soung Min KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2019;45(5):260-266
OBJECTIVES: Dental implants shorter than 8 mm, called short dental implants (SDIs), have been considered to have a lower success rate than standard length implants. But recent studies have shown that SDIs have a comparable success rate, and implant diameter was more important for implant survival than implant length. Also, SDIs have many advantages, such as no need for sinus lifting or vertical bone grafting, which may limit use in medically compromised patients. MATERIALS AND METHODS: In this study, 33 patients with 47 implants 7-mm long were examined over the last four years. All patients had special medical history and were categorized into 3 groups: systemic disorders, such as diabetes mellitus (controlled or uncontrolled), mental disability, and uncontrolled hypertension; oral cancer ablation with reconstruction, with or without radiotherapy; diverse osteomyelitis, such as osteoradionecrosis and bisphosphonate-related osteonecrosis of the jaw. Most of these patients have insufficient residual bone quality due to mandible atrophy or sinus pneumatization. RESULTS: The implant diameters were 4.0 (n=38), 4.5 (n=8), and 5.0 mm (n=1). Among the 47 implants placed, 2 implants failed before the last follow-up. The survival rate of 7-mm SDIs was 95.74% from stage I surgery to the last follow-up. Survival rates did not differ according to implant diameter. The mean marginal bone loss (MBL) at 3 months, 1 and 2 years was significantly higher than at implant installation, and the MBL at 1 year was also significantly higher than at 3 months. MBL at 1 and 2 years did not differ significantly. CONCLUSION: Within the limitations of the present study, the results indicate that SDIs provide a reliable treatment, especially for medically compromised patients, to avoid sinus lifting or vertical bone grafting. Further, long-term follow-up is needed.
Alveolar Bone Loss
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Atrophy
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Bisphosphonate-Associated Osteonecrosis of the Jaw
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Bone Transplantation
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Dental Implants
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Diabetes Mellitus
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Follow-Up Studies
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Humans
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Hypertension
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Lifting
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Mandible
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Mouth Neoplasms
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Osteomyelitis
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Osteoradionecrosis
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Radiotherapy
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Retrospective Studies
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Survival Rate
6.Large myxomatous odontogenic tumor in the jaw: a case series
Truc Thi Hoang NGUYEN ; Mi Young EO ; Yun Ju CHO ; Hoon MYOUNG ; Soung Min KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2021;47(2):112-119
Objectives:
Myxomatous odontogenic tumors (MOTs) are the third most common odontogenic tumors in the oral and maxillofacial region. Due to its slow-growing, but locally invasive nature, the tumor is usually detected by accident or only when it becomes a large mass, which causes facial deformity.
Materials and Methods:
Current study reports three unusual cases of MOT including huge myxoma involve the mandible in middle-aged man, MOT with ossifying fibroma pattern in mandible, and MOT in maxilla of young female patient. The diagnosis and treatment strategy of MOTs was also summarized and updated.
Results:
In reported three cases of patients with large MOTs, surgical treatment was indicated with fibular free flap reconstruction in the mandible and plate reconstruction in the maxilla. The tumors were successfully treated with radical resection and did not show signs of recurrence during the followup period.
Conclusion
Surgical treatment indication depends on size, the position of the lesion, patient systemic condition and surgeon individual experience.In the case of a large tumor, radical resection and reconstruction is the standard surgical strategy. The conservative surgical treatment including enucleation with wide curettage is still under controversy. The recurrence rate for MOTs is significantly high, up to 30%, therefore long-term follow-up is essential.
7.Salivary biomarkers in oral squamous cell carcinoma
Truc Thi Hoang NGUYEN ; Buyanbileg SODNOM-ISH ; Sung Weon CHOI ; Hyo-Il JUNG ; Jaewook CHO ; Inseong HWANG ; Soung Min KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2020;46(5):301-312
In disease diagnostics and health surveillance, the use of saliva has potential because its collection is convenient and noninvasive. Over the past two decades, the development of salivary utilization for the early detection of cancer, especially oral cavity and oropharynx cancer has gained the interest of the researcher and clinician. Until recently, the oral cavity and oropharynx cancers are still having a five-year survival rate of 62%, one of the lowest in all major human cancers. More than 90% of oral cancers are oral squamous cell carcinoma (OSCC). Despite the ease of accessing the oral cavity in clinical examination, most OSCC lesions are not diagnosed in the early stage, which is suggested to be the main cause of the low survival rate. Many studies have been performed and reported more than 100 potential saliva biomarkers for OSCC. However, there are still obstacles in figuring out the reliable OSCC salivary biomarkers and the clinical application of the early diagnosis protocol. The current review article discusses the emerging issues and is hoped to raise awareness of this topic in both researchers and clinicians. We also suggested the potential salivary biomarkers that are reliable, specific, and sensitive for the early detection of OSCC.
8.Scalp injury management by a maxillofacial surgeon in a low-resource hospital
Paul FRIMPONG ; Truc Thi Hoang NGUYEN ; Edinam Salia NIMATU ; Emmanuel Kofi AMPONSAH ; Soung Min KIM
Maxillofacial Plastic and Reconstructive Surgery 2020;42(1):39-
Background:
Head or scalp injury is a life-threatening and typically accidental human injury. Most medical departments require immediate medical treatment and proper treatment with specialized medical personnel and facilities. However, in low-resource environments, such as the rural region of West Africa, the authors have treated emergency trauma patients and provided immediate treatment despite lack of resources.Case presentationWe reviewed three cases of scalp injury patients, with representative clinical information, and used these cases to outline feedback on scalp trauma treatment based on the specialty knowledge of general and emergency surgeon.
Conclusions
Oral and maxillofacial surgeons are medical specialists that can immediately diagnose and treat these scalp injuries based on their medical knowledge and experience with the maxillofacial region.
9.7-mm-long dental implants: retrospective clinical outcomes in medically compromised patients
Truc Thi Hoang NGUYEN ; Mi Young EO ; Yun Ju CHO ; Hoon MYOUNG ; Soung Min KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2019;45(5):260-266
OBJECTIVES:
Dental implants shorter than 8 mm, called short dental implants (SDIs), have been considered to have a lower success rate than standard length implants. But recent studies have shown that SDIs have a comparable success rate, and implant diameter was more important for implant survival than implant length. Also, SDIs have many advantages, such as no need for sinus lifting or vertical bone grafting, which may limit use in medically compromised patients.
MATERIALS AND METHODS:
In this study, 33 patients with 47 implants 7-mm long were examined over the last four years. All patients had special medical history and were categorized into 3 groups: systemic disorders, such as diabetes mellitus (controlled or uncontrolled), mental disability, and uncontrolled hypertension; oral cancer ablation with reconstruction, with or without radiotherapy; diverse osteomyelitis, such as osteoradionecrosis and bisphosphonate-related osteonecrosis of the jaw. Most of these patients have insufficient residual bone quality due to mandible atrophy or sinus pneumatization.
RESULTS:
The implant diameters were 4.0 (n=38), 4.5 (n=8), and 5.0 mm (n=1). Among the 47 implants placed, 2 implants failed before the last follow-up. The survival rate of 7-mm SDIs was 95.74% from stage I surgery to the last follow-up. Survival rates did not differ according to implant diameter. The mean marginal bone loss (MBL) at 3 months, 1 and 2 years was significantly higher than at implant installation, and the MBL at 1 year was also significantly higher than at 3 months. MBL at 1 and 2 years did not differ significantly.
CONCLUSION
Within the limitations of the present study, the results indicate that SDIs provide a reliable treatment, especially for medically compromised patients, to avoid sinus lifting or vertical bone grafting. Further, long-term follow-up is needed.
10.Solitary plasmacytoma in the maxillary sinus: 10-year follow-up
Truc Thi Hoang NGUYEN ; Mi Young EO ; Buyanbileg SODNOM-ISH ; Yun Ju CHO ; Soung Min KIM
Journal of the Korean Association of Oral and Maxillofacial Surgeons 2021;47(6):471-475
Solitary plasmacytoma (SP) is an uncommon form of plasma cell neoplasm occurring intraosseously or in soft tissue and presents as a single mass of monoclonal plasma cells. SP in the maxillary sinus is rare and can be misdiagnosed as other maxillary sinus tumors. The essential examinations in patients with the initial diagnosis of plasmacytoma are bone marrow biopsy, serum and urine electrophoresis, and kappa/lambda ratio (κ:λ ratio) to rule out multiple myeloma (MM). Herein, a rare case of SP in the maxillary sinus treated by surgery and localized radiation is reported. At the 10-year follow-up examination, local recurrence or disseminated development of MM were not evident.