5.Evaluation of Direct Rapid Immunohistochemical test (DRIT) of Canis lupus familiaris hippocampal touch impression smears using a monospecific polyclonal antibody for rabies virus detection.
Ang C. Mary Jasmin ; Llenaresas-Manalo Daria ; Jarilla Blanca ; Tuason Laarni ; Avenido Eleonor ; Demetria Catalino ; Medina Plebeian ; Quaimbao Beatriz ; Acosta Luz ; Inoue Satoshi ; Estacio Ma. Amelita
Acta Medica Philippina 2016;50(2):51-55
BACKGROUND: Rabies is an important zoonotic disease that needs to be eradicated worldwide. It is still prevalent in the Philippines, thus development of a relatively affordable but still accurate and rapid post-mortem detection test for the virus is desired, especially in regional laboratories.
METHODS:The study evaluated the Direct Rapid Immunohistochemical Testing (DRIT) of hippocampal touch impressions of suspected rabid Canis lupus familiaris using monospecific N protein polyclonal antibody developed by the Research Institute for Tropical Medicine (RITM). One hundred sixty (160) acetone-fixed hippocampal touch impressions were subjected DRIT.
RESULTS: One hundred thirteen (70.6%) out of 160 samples tested positive for rabies viral antigen (RVA) and 47 (29.4%) out of 160 samples tested negative for RVA. No false positive and false negative results were obtained. The results agree with the gold standard, dFAT.
CONCLUSION: DRIT was able to detect low to high concentrations of RVA in the hippocampal touch impressions based on the grading distribution. DRIT had 100% sensitivity, specificity and over-all accuracy using monospecific polyclonal antibodies, which suggests its use as a more affordable alternative to the gold standard dFAT.
Animal ; Antigens, Viral ; Dogs ; Hippocampus ; Rabies ; Rabies Virus ; Sensitivity And Specificity ; Touch ; Tropical Medicine ; Immunohistochemistry
6.Squamous cell carcinoma of the scalp: A case report.
Lacuesta Maricarr Pamela M ; Ong Natalia P ; Crisóstomo Trisha C ; Gabriel Ma. Teresita G
Journal of the Philippine Dermatological Society 2008;17(1):31-34
Nonmelanoma skin cancers are the most common human cancers. To this group basal cell carcinoma and cutaneous squamous cell carcinoma. Squamous cell carcinoma (SCC) is the second most common skin cancer in darkly pigmented patients and majority of the SCC's develop in non-sun exposed areas. We describe a case of a 72-year old male who consulted in the outpatient department of the Research Institute for Tropical Medicine for a 2-month history of non-healing ulcer on the scalp. Histopathologic examination revealed diagnosis of invasive squamous cell carcinoma. Patient was referred for surgical excision.
Human ; Male ; Aged ; Carcinoma, Basal Cell ; Carcinoma, Squamous Cell ; Outpatients ; Scalp ; Skin Neoplasms ; Tropical Medicine ; Ulcer
7.Albert Schweitzer (1875-1965): a reverence for life.
Siang Yong TAN ; Yvonne TATSUMURA
Singapore medical journal 2014;55(7):351-352
Africa
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Altruism
;
Biology
;
Europe
;
Gabon
;
History, 19th Century
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History, 20th Century
;
Humans
;
Philately
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Philosophy, Medical
;
history
;
Tropical Medicine
;
history
8.The Geopolitics of Tropical Diseases: A Geo-epidemiological Perspective.
Korean Journal of Medical History 2005;14(2):151-170
The objective of my article is to investigate how the West had strong interest in tropical diseases and developed tropical medicine and hygiene from the 1870s through the 1910s. Its focus is to identify the geopolitical conditions in which the West constructed 'tropical diseases'to extend its imperial interests into non-Western tropical regions. The article has several specific research tasks: first, I attempt to explore the way in which European people transformed their attitudes toward tropical diseases from the sixteenth century to the 1860s. A variety of writings by European physicians are discussed; the second part shows European change in its domestic sanitary situation in relation to its imperial interests in tropical regions. Sanitary hygiene in metropole and colonies are not separate, but interconnected; third, the paper illuminates how the West responded to the spread of 'Asiatic cholera' in the nineteenth century. Cholera provides a typical example for the West to perceive Asian origin of tropical diseases; finally, the article demonstrates that hygienic governance of tropical diseases is the key to imperial dominion over colonies by taking the Panama Canal as an example. Although several European countries such as Spain, Britain, Germany, and France had strong imperial interests in the Panama Canal that might facilitate trade between the Atlantic and the Pacific, they failed to occupy the canal because of their inability to control high prevalence of malaria and yellow fever. Taking advantage of 'tropical medicine, ' the United States succeeded in taking up the canal by eradicating tropical diseases in the canal. It was owing to the scientific development of tropical hygiene and medicine that the West transformed its pessimistic into optimistic position about the colonization of tropical regions. Tropical diseases became the geopolitical reference for Western conceptualization of Asia, Africa, Latin America, and the Pacific.
Tropical Medicine/*history
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Sanitation/history
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Hygiene/*history
;
Humans
;
History, 20th Century
;
History, 19th Century
;
Europe
;
Colonialism/history
;
Cholera/epidemiology/*history
;
Attitude of Health Personnel
9.Who Neglects Neglected Tropical Diseases? - Korean Perspective.
Min Ho CHOI ; Jae Ran YU ; Sung Tae HONG
Journal of Korean Medical Science 2015;30(Suppl 2):S122-S130
Neglected tropical diseases (NTDs) are a group of tropical infectious diseases of poorest people. Of 17 NTDs managed by WHO, two, guinea worm disease (by 2015) and yaws (by 2020) are targeted for eradication, and four (blinding trachoma, human African trypanosomiasis, leprosy, and lymphatic filariasis) for elimination by 2020. The goals look promising but 11 others are still highly prevalent. Soil-transmitted helminths (STHs) are one NTD which prevail over the world including temperate zones. They had been highly prevalent in Korea but are mostly disappearing at present through systematic and sustainable control activity. The successful experience of STH control enables Korean experts to develop many programs of NTD control in developing countries. Several programs of both official development aid and non-governmental organizations are now targeting NTDs. Most NTDs are low in health priority compared to their health threats because they are chronic, insidious, and of low mortality. No one, including the victims, raised priority of NTD control with a loud voice in the endemic field of the diseases. After the millennium development goals declared disease control over the world, NTDs are becoming less neglected globally. Even with limited resources, beginning a sustainable national program is the key for the control and elimination of NTDs. No more neglect, especially no more self-neglect, can eliminate diseases and upgrade quality of life of the neglected people.
Communicable Disease Control/*organization & administration
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*Developing Countries
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Global Health
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Humans
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*International Cooperation
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Neglected Diseases/diagnosis/*epidemiology/*prevention & control
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Population Surveillance/methods
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Republic of Korea
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Tropical Medicine/*organization & administration
10.Writing in the time of COVID-19 pandemic
Journal of the Philippine Dermatological Society 2020;29(1):5-5
Consultants
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Social Media
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Social Isolation
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Quarantine
;
Tropical Medicine
;
Pleasure
;
Pandemics
;
Dermatology
;
COVID-19
;
Dermatologists
;
Fellowships and Scholarships
;
Writing
;
Research Personnel
;
Schools
;
Publishing
;
Videoconferencing
;
Surveys and Questionnaires
;
Research
;
Anxiety
;
Fear