1.Preliminary assessment of the side effects of some chemotherapy to treat malignant diseases of hematopoietic organs
Journal of Practical Medicine 2003;450(4):49-51
From 1995 to 2002, 364 courses of chemotherapy with different regimens, almost gave various side effects such as leucopenia, thrombocytopenia, hypohemoglobin, increase of liver enzymes (SGOT, SGPT,…), enhance urea, creatinine level, nausea, alopecia… with different severity and incidence. The common regimans with more significant side effects were Doxorubicin + AraC (P3), MOPP (P2), CHDP (P1) and VAD (P4); the regimens AraC + Depersolon (P7), Hydrea + AraC (P6) and particularly Hydrea alone (P5) gave usually less side effects
drug therapy
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Hematinics
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Diseases
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Therapeutics
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adverse effects
2.Preliminary assessment of adverse side effects of some procedure of chemotherapy against malignancy of hemopoietic organs
Journal of Practical Medicine 2003;463(10):44-46
Most of chemical drafts that treatment malignant disease at blood- forming organs have side effects as: reduce aleukemia, glomerule, blood pigment, increase ure, creatinin or nauseate, voltmit, lose hair. However, rate and level are different in each of drafts. The other drafts, that made side effects are Doxorubicin + Ara.C (P3), MOPP (P2), CHOP (P1) and VAD (P4). Ara.C + Depersolon (P7), Hydrea + Ara.C (P6) drafts and especially is only use single Hydrea dafts that has little side-effect
Hematologic Neoplasms
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drug therapy
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Pharmaceutical Preparations
3.Investigation of HBeAg marker and anti HBe in subjects with positive HBsAg
Journal of Practical Medicine 2003;442(2):96-98
In 242 subjects (68 female, 174 male), ELISA technique was performed with the set of ORGANON TEKNIKA UNIFORM II. Result showed a HBeAg positive rate of 37.42% on HBsAg positive subjects.
The rate of HBsAg positive subjects having anti HBsAg is 56.61%. In 38.9% of B viral hepatitis patients, recession of the condition was noted on laboratory examinations
Hepatitis B Surface Antigens
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Hepatitis B e Antigens
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Diseases
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Liver Diseases
4.Study on some laboratory test indicators of hemostasis and blood coagulation in normal persons
Journal of Practical Medicine 2003;445(3):20-23
120 normal subjects without bleeding history aged 20-77 were studied. Bleeding time 169 seconds, there is no significant statistic difference in genders and age groups. Plasma fibrinogen level was 2.56 g/l, no significant difference in 2 genders. In the under 45 years old group, fibrinogen level was lower than in above 45 yeas old group with statistical significant. No case of non-contracted blood clot occured, 2.5% of blood clot was contrated non completely, 97.5% completely. Alcohol test was negative in all cases. No case of fibrinolyse time < 90 minutes occured.
Hemostasis
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Blood Coagulation
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Laboratories
5.Values of fibrinogen degradation products (FDPs) and D-dimmer in healthy people
Journal of Practical Medicine 2002;435(11):42-43
The study involved 32 healthy blood donors (16 men and 6 women). Plasma D-dimer and FDPs levels were determined by semi-quantitative method, using chemical procedure of the Stago Inc., France. The results showed that plasma FDPs level in healthy people was lower than 40 g/ml (93.75% of the participants had lees than 20 g/ml). Plasma D-dimer level was 1-4 g/ml, with 75% of the participants had D-dimer values ranged from 1 to 2 g/ml.
Fibrin Fibrinogen Degradation Products
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Pharmaceutical Preparations
6.Primarily results of the application of test hemoglobin A1c (HBA1C) in the clinical diagnosis and treatment of the diabetes mellitus
Journal of Practical Medicine 2000;392(12):42-44
A study on the 55 patients (27 patients with diabetes mellitus and 28 patients with the suspecting of diabetes mellitus) in the hematology and blood transfusion department of friendship hospital was carried out. The patients received the quantitative analysis of HbA1C by Diastat. The relation of HbA1C with glycemia was evaluated. The results were reported that the rate of patients with the high concentration of HbA1C is valuable. There was a direct correlation between HbA1C and glycemia in the most of patients.
Diabetes Mellitus
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diagnosis
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therapeutics
7.The serum viscosity in Vietnam people
Pharmaceutical Journal 2002;318(10):56-58
The evaluation of serum viscosity contributes to the diagnosis of some hematopathology, cardiopathology. A study on 303 healthy persons with ages of 18-81 in Hanoi was carried out to determine the Vietnamese serum viscosity. The results have shown that the serum viscosity found in the normal people was 9.180.47 (1.52-2.45). There is no significant different of the serum viscosity between men and women. The serum viscosity is gradually increased as increased age.
Viscosity
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serum
8.Treatment of myelodysplasia syndrome
Journal of Medical and Pharmaceutical Information 2003;0(5):16-22
Myelodysplasia syndrome is a diseases group of which quite
difficult cure and prediction. There are many treatment methods however it depends on patient’s age, level of diease, rate of blast in bone marrow. The treatment includes: chemical treatment, trasplant originative cell, support treatment. Other method is combination of various treatment methods: Use Ara-C combine with depersolon, chemical treatment combine with stimulative agent of blood and trasplant originative cell
Neural Tube Defects
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Bone Marrow
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Cytarabine
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Therapeutics
9.Blood transfusion at Huu Nghi Hospital between 1/1985 and 5/2000
Journal of Practical Medicine 2002;430(9):10-12
For more than 15 years (1985 - 2000), there were 8100 blood transfusions performed at the H÷u NghÞ Hospital using 9486 blood units/products (average 1.17 blood units per case). Blood transfusion need of patients, frequency of transfused blood group, features of canceled blood and percentage of transfused blood amount of departments were followed. The results showed that the need of blood transfusion was raising. Group O blood was the most used and group AB was least used. Departments of Surgery, Clinical Hematology, Intensive Care and Hemodialysis used abundant blood transfusion for pathological conditions, including gastric and intestinal conditions, leukemia, myelodysplasia syndrome and bone marrow failure.
Blood transfusion
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hospitals
10.Clinical and epidemiological features of bone marrow failure
Journal of Practical Medicine 2000;383(6):12-14
From 26 patients with bone marrow failure, we had drawn some following remarks:- Over 50% of the patients is in the ages from 61 to 75 years old. (youngest: 42: oldest: 82 years old).- There were 38.46% of the patients that were used to contact with some causes of AA in their history particalarly 11.54%- using cloramphenicol; and 7.69% used to live in the area with American orange toxicant. - 100% of the patient with anemia; 15.36% with anemia + hemorrhage; then anemia + infection (7.69%) and anemia + hemorrahage + infection(7.69%).
Bone Marrow Diseases
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diagnosis
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Epidemiologic Studies