1. Usefulness of Virtual 3D image analysis in laparoscopic gastrectomy for trainee surgeons
Masaaki NISHI ; Kozo YOSHIKAWA ; Jun HIGASHIJIMA ; Takuya TOKUNAGA ; Toshihiro NAKAO ; Chie TAKASU ; Shohei ETO ; Hiroki TERAOKU ; Mistuo SHIMADA
Innovation 2014;8(4):114-115
Background: Laparoscopic gastrectomy has several difficult points including,lymph node dissection and resection of several blood vessels for trainee surgeons.Recently, preoperative evaluation of vasculature based three-dimensional (3D)imaging technique resulted in a significantly improved clinical outcome inabdominal surgery. The aim of this study is to investigate the usefulness of the 3Dimage in laparoscopic gastrectomy for trainee surgeons.Method: We adopted a multiphase CT protocol to acquire 3 image sets (arterial,portal, and equilibrium phases). 3D-reconstruction of gastric vasculature wasmade using data from a contrast enhanced MDCT and SYNAPSE VINCENTsoftware. Whole pancreas, spleen, gastric vasculature were extracted from MDCTscans and traced. Thirty three patients, who underwent laparoscopic gastrectomyfor gastric cancer during the period between Jan 2013 and May 2014 wereexamined in this study. Four trainees performed a 19 laparoscopic gastrectomy,while 14 laparoscopic gastrectomy were conducted by the two trainers. Thesurgical outcomes in both groups and the pattern of gastric vasculatures wereevaluated.Result: 3D imaging technique showed a correct positional relationship betweenthe stomach, gastric vessels, pancreas and spleen. Surgical outcome includingestimated blood loss, and operative time in trainee group were not significantlydifferent compared to trainer group. 3D imaging technique showed a correctpositional relationship between the stomach, gastric vessels, pancreas and spleen.Regarding vascular pattern detected by 3D imaging, the origins of IPA were RGEAin 12 cases (36%), GDA in 8 cases (24%).bifurcation of RGEA and GDA in7 cases(21%), and not detected in 1 case (3%), respectively. The types of confluence ofIPV were RGEV in 16 cases (48%), ASPDV in 10 cases (30%), and not detectedin 7 cases (21%), respectively.Conclusions: 3D imaging technique might contribute to successful laparoscopicgastrectomy. Preoperative 3D-simulation techniques enabled trainee surgeons toeasily and safely perform laparoscopic gastrectomy.
2.Usefulness of Virtual 3D image analysis in laparoscopic gastrectomy for trainee surgeons
Masaaki Nishi ; Kozo Yoshikawa ; Jun Higashijima ; Takuya Tokunaga ; Toshihiro Nakao ; Chie Takasu ; Shohei Eto ; Hiroki Teraoku ; Mistuo Shimada
Innovation 2014;8(4):114-115
Background: Laparoscopic gastrectomy has several difficult points including,
lymph node dissection and resection of several blood vessels for trainee surgeons.
Recently, preoperative evaluation of vasculature based three-dimensional (3D)
imaging technique resulted in a significantly improved clinical outcome in
abdominal surgery. The aim of this study is to investigate the usefulness of the 3D
image in laparoscopic gastrectomy for trainee surgeons.
Method: We adopted a multiphase CT protocol to acquire 3 image sets (arterial,
portal, and equilibrium phases). 3D-reconstruction of gastric vasculature was
made using data from a contrast enhanced MDCT and SYNAPSE VINCENT
software. Whole pancreas, spleen, gastric vasculature were extracted from MDCT
scans and traced. Thirty three patients, who underwent laparoscopic gastrectomy
for gastric cancer during the period between Jan 2013 and May 2014 were
examined in this study. Four trainees performed a 19 laparoscopic gastrectomy,
while 14 laparoscopic gastrectomy were conducted by the two trainers. The
surgical outcomes in both groups and the pattern of gastric vasculatures were
evaluated.
Result: 3D imaging technique showed a correct positional relationship between
the stomach, gastric vessels, pancreas and spleen. Surgical outcome including
estimated blood loss, and operative time in trainee group were not significantly
different compared to trainer group. 3D imaging technique showed a correct
positional relationship between the stomach, gastric vessels, pancreas and spleen.
Regarding vascular pattern detected by 3D imaging, the origins of IPA were RGEA
in 12 cases (36%), GDA in 8 cases (24%).bifurcation of RGEA and GDA in7 cases
(21%), and not detected in 1 case (3%), respectively. The types of confluence of
IPV were RGEV in 16 cases (48%), ASPDV in 10 cases (30%), and not detected
in 7 cases (21%), respectively.
Conclusions: 3D imaging technique might contribute to successful laparoscopic
gastrectomy. Preoperative 3D-simulation techniques enabled trainee surgeons to
easily and safely perform laparoscopic gastrectomy.
3.Genetic polymorphisms ofCYP2A6 andCYP2E1 with tobacco smoking is not associated with risk of urothelial cancer.
Hiromasa TSUKINO ; Yoshiki KURODA ; Hiroyuki NAKAO ; Hirohisa IMAI ; Yukio OSADA ; Hisato INATOMI ; Kyoko KITAGAWA ; Toshihiro KAWAMOTO ; Takahiko KATOH
Environmental Health and Preventive Medicine 2002;7(3):129-131
OBJECTIVESTo elucidate the association between genetic polymorphisms ofCYP2a6 andCYP2E1 and urothelial cancer susceptibility.
METHODSA total of 137 Japanese patients with urothelial cancer and 217 Japanese healthy controls, frequency-matched for age and gender, were selected. The polymorphisms ofCYP2A6 andCYP2E1 were analyzed by PCR-RFLP, and cigarette smoking histories were obtained through interviews
RESULTSThe frequency ofCYP2A6 homozygote deletion genotype was 2.9% in the patients, compared with 3.2% in the controls (OR=0.84, 95% CI 0.24-2.96). The frequencies ofCYP2E1 C1/c2 andC2/c2 were 27.7% and 4.4% in the patients, compared with 35.5% and 6.0% in the controls (OR=0.68, 95% CI 0.42-1.09, OR=0.67, 95% CI 0.24-1.84, respectively). No statistically significant differences were observed when theCYP2A6 homozygote deletion genotype and theCYP2E1 genotypes were examined relative to smoking status.
CONCLUSIONSOur data indicate that neither a relationship between genetically impaired nitrosamine metabolism and tobacco-smoking consumption, nor urothelial cancer risk related to theCYP2A6 deletion genotype andCYP2E1 Rsa I genotype was found in Japanese population.
4.Prevalence of burnout among public health nurses in charge of mental health services and emergency care systems in Japan.
Hirohisa IMAI ; Hiroyuki NAKAO ; Yoshihiko NAKAGI ; Satoko NIWATA ; Yoshihiko SUGIOKA ; Toshihiro ITOH ; Takahiko YOSHIDA
Environmental Health and Preventive Medicine 2006;11(6):286-291
OBJECTIVESThe Community Health Act came into effect in 1997 in Japan. This act altered the work system for public health nurses (PHNs) in public health centers (PHCs) nationwide from region-specific to service-specific work. Such major changes to working environment in the new system seem to be exposing PHNs to various types of stress. The present study examined whether prevalence of burnout is higher among PHNs in charge of mental health services (psychiatric PHNs) than among PHNs in charge of other services (non-psychiatric PHNs), and whether attributes of emergency mental health care systems in communities are associated with increased prevalence of burnout.
METHODSA questionnaire including the Pines burnout scale for measuring burnout was mailed to 525 psychiatric PHNs and 525 non-psychiatric PHNs. The 785 respondents included in the final analysis comprised 396 psychiatric PHNs and 389 non-psychiatric PHNs.
RESULTSPrevalence of burnout was significantly higher for psychiatric PHNs (59.2%) than for non-psychiatric PHNs (51.5%). When prevalence of burnout in each group was analyzed in relation to question responses regarding emergency service and patient referral systems, prevalence of burnout for psychiatric PHNs displayed significant correlations to frequency of cases requiring overtime emergency services, difficulties referring patients, and a feeling of "restriction".
CONCLUSIONSPrevalence of burnout is high among psychiatric PHNs, and inadequate emergency mental health service systems contribute to burnout among these nurses. Countermeasures for preventing such burnout should be taken as soon as possible.