Nasolacrimal duct stenosis, which causes epiphora and eye mucus, is generally treated with probing and irrigation of the nasolacrimal duct. A 57-year-old woman was treated with probing and irrigation of the nasolacrimal duct three times, however, her symptoms of refractory nasolacrimal duct stenosis did not improve. Following 3 days administration of saisoin, her epiphora ameliorated. Based on this experience, we treated 11 adult patients with nasolacrimal duct stenosis using saisoin, and 10 (90.9%) achieved remission within a week. All the adult patients had received treatment by probing and irrigation of the nasolacrimal duct at an ophthalmological clinic, and their symptoms had not improved. Two such cases in infants, moreover, were cured with saisoin in a week. This is the first report on the efficacy of saisoin for the treatment of nasolacrimal duct stenosis in Japan.

Mycobacterial infection after open-heart surgery is a rare complication. We report 2 cases of cutaneous infection caused by Mycobacterium fortuitum (M. fortuitum). Case 1: A 56-year-old man had wound infection from the 10th postoperative day (POD). The growth of M. fortuitum was detected on the 38th POD. Combination of multiple antibiotic therapy was performed. He was cured after several recurrences of cutaneous ulcer and abscess following 15 months. Case 2: A 26-year-old man had wound infection from the 28th POD. Deep sternal infection with mediastinitis developed. Bacteriological examination revealed the growth of M. fortuitum on the 61st POD. Omentopexy was performed on the 67th POD. Wound infection completely healed, and the patient was discharged from our hospital on the 137th POD. Mycobacterial infection should be considered when the wound infection is resistant to ordina antibiotics.