1.In Vitro Dissolution Test of Flavonoid Pilulae from Gegen
Chinese Traditional and Herbal Drugs 1994;0(06):-
Flavonoid Pilulae from Gegen were prepared by melting method. Using PEG 4000 and PEG 6000 as carrier. Serious of studies on the in yitro release kinetics were carried out.PEG4000 ; PEG6000 ratio had no effect on the release kinetics. PEG 4000: flavonoids ratio had an evident effect on the release properties of the pilulae, the higher the ratio,the faster the release rate. But when the PEG 4000, flavonoids ratio exceeded 10: 1, a reverse effect could be seen. Compared with "Gegen flavonoids" tablets, "Yufengingxin" tablets(release half time, T50= 94.79min), the pilulae gave a much fast release characteristic (T50 = 11. 56min).
2.Differences between Tetra-ataxiametry and Berg balance scale in the prediction value for the fall risk of elderly inpatients
Chunyan ZHAO ; Yan ZHOU ; Huihua ZHAO ; Ying WANG ; Yiqing CHEN ; Tongying JIANG ; Ping LYU ; Lingjun LI ; Huili HE
Chinese Journal of Modern Nursing 2017;23(29):3717-3721
Objective To compare the difference and effectiveness between Tetra-ataxiametry and Berg balance scale (BBS) in predicting the risk for fall in the elderly inpatients.Methods A total of 401 elderly inpatients were randomly selected using convenience sampling in a class III grade A hospital. Tetra-ataxiametry and BBS were used to monitor the risk for falls of elderly patients in two groups: group with or without fall histories.Results Fall histories were set as the standard. The area ratios under receiver operating characteristic (ROC) of Tetra-ataxiametry fall index (FI) and BBS were 0.762 and 0.705. Youden index showed that the predicted value, the sensibility and the specificity of Tetra-ataxiametry FI were 41, 80.5% and 60.2%; while those for BBS were 46, 67.1% and 65.8%. No statistically significant difference in the area under the curve (AUC) between Tetra-ataxiametry and BBS was observed(P=0.0587).Conclusions There is no statistically significant difference in predicting the risk for fall in the elderly inpatients between Tetra-ataxiametry and BBS, suggesting that Tetra-ataxiametry can replace BBS to evaluate the fall risk, and is better than BBS, since Tetra-ataxiametry has higher sensitivity in objective data provision, body weight and BMI (body mass index).