The ultrasonography is a good method for diagnosis of the thyroid nodules: 250 random selected patients in B¹ch Mai Hospital were examined and have radiation iodine image, quantitative analysis of blood TSH, ultrasound diagnosis. Results: the combination clinical examination with para-clinical tests was very necessary, especially the cytological diagnosis. The blood level of TSH is insignificant value in determined diagnosis. It should consider the ultrasound of thyroid as regular test in diagnosis of thyroid nodule
Thyroid Nodule ; Diagnosis

The second step of immunoglobulin gene alteration consists of somatic hypermutation and class switch recombination. 80th are regulated by activation-induced cytidine deaminase (AID). Methods: Study on possible application of class switch recombination assays for immunoglobulin gene alteration via AID. Cell based assays using AID B lymphocyte and NIH3T3 cell carrying switch substrate; gene transfer using retrovirus system; FACS analysis; PCR and ELISA. Results: DNA sequencing for S region and gamma1CT are the most sensitive and accurate assays. However, gamma1CT assay seemed to be more reliable and applicable. Others are accurate assays but less applicable. Conclusion: gamma1CT determination is the best class switch recombination assay for immunoglobulin gene alteration via AID.
Immunoglobulins, Genes

A survery was conducted on 1069 subjects aged 20- 74 years old(male 47%, female 53%) living in Ha Noi, concerning the diabetes status. Results showed no difference in term of genders but geographically, in urban areas the prevalence was 2 times higher than in the suburb. The number of diabetes patients of under secondary level were 21 times higher than the higher level. Among the hand worker, the prevalence was lower than in sedentary workers. The prevalence was also low in the intellectuals.
Diabetes Mellitus ; Glucose ; Epidemiology

Now a day the researchers still continue to determine whether genetic factors are the leading cause of Alzheimer disease (AD). Mutations of one in three genes (PSEN1, PSEN2, and APP) were identified causes of early AD. However, the percentage of patients with early AD is small. Although there wasn’t any genetic factors directly related to late-onset AD, in the last decades, genes of some risk factors leaded to this disease were determined more and more, especially genes caused vascular diseases. APOE was considered as highest risk factors for both of AD and vascular diseases. The risk factors of gene must be explained and put into the context of closed relations to the environment, nationality, geography and territory.
Dementia, Diagnosis , Molecular Biology

Luu Hoang with its yellow colour, spongy consistency, sour taste, toxicity, can infultrate inward through the medians of kidney and large bowel. Oral use of Luu Hoang can tossify the “fire”, assiste the “yang”. Topic use can detoxicate, kill the parasite, treat the pimples, Luu Hoang abates the itch in cases of scale, fungi on skin, eczema. Luu Hoang is used in the conditions of boil, the cold in kidney, coldish impaired “yang”, coldish secretion, difficulty in faces exerete and urinate. Oral use of 1-3 g in powder and pill, topic use with powder spreaded in the wound… are the most common methods. Counter indications are in the cases of impaired “iin”, exceeded “fire”, pregnancy, and incompatible with Phac Tieu
Medicine, Traditional ; Therapeutics ; Pharmaceutical Preparations

Fructose 1,6 bisphosphate adolase A and C (FPA A4 and C44) have been found to bind specifically to heparin in physiological ionic strength. The researcher found that activity of FPA was inhibited by heparin. The inhibition of FPA A4 and C4 depend on the degree of sulfation. Inhibition activity FPA of heparin increase directly proportional to molecule lenghth. Kinetic studies showed that: inhibitory mode of heparin on FPA was the linear mixed type inhibition, in which velocity can be driven to zero at high heparin concentration
Kinetics ; Fructose-Bisphosphate Aldolase ; Heparin

From June 2001 to June 2003, at HCM city Children Hospital N01 and Tien Giang General Hospital, 320 cases of Dengue hemorrhagy were studied prospectively. All cases were dignosed definitely by serology IgM-ELISA HI reaction. Logistic regression analysis showed the related factors for prolonging the dengue hemorrhagic fever shock: age 5-9 years old, fever episode, gastrointestinal hemorrhagy, liver failure, hypoglycemia, hyponatrimia, metabolic acidosis, blood coagulation disturbance, delay of diagnosis, no-accuracy treatment, no proper follow up, tremble with perfusion.
Dengue Hemorrhagic Fever ; child ; Disease ; Shock

Research on 1060 people who from 20 to 74 years old live in Hanoi. 47% of them was man and 53% was woman. Result: eating and drinking habit has importance effect to the development of diabetes disease. People who eat much fat, drink much beer and eat little vegetable have higher risk of suffering diabetes to use little fat, don’t drink beer and smoke tobacco, and eat more vegetable. People who live in city eat vegetable, fruit and smoke less than suburban but they drink beer much than suburban. Body activity has close relation to the disease condition
metabolism ; Nutrition Therapy ; Motor Activity

“Antiitchy B” tablets were processed from herbal medicines including prepared Rchmannia glutinosa, Angelica sinensis, Paeonia lactiflora, Salvia miltiorrhiza, Glycyrrhiza uralensis, and Sophora flavescens, plus shells of Ostrea gigas and Ketotifen. Experimental study carried on mice with allergic contact dermatitis showed that “antiitchy B” tablets significantly inhibited dinitrofluobenzene induced allergic inflammation in mice ears epidermis
Medicine, Traditional ; Dermatitis, Allergic Contact ; Medicine, Herbal ; drugs

Iodine concentrations of water samples, vegetable samples and soil samples in Kien Thanh commune (KT) – Cho Moi district – An Giang province were compared with those of Duyen Ha commune (DH) – Thanh Tri district – Ha Noi city. Iodine intake of KT people was about 60 mg daily. 70.1% of urine samples had low iodine concentration. Iodine concentration in water, soil and vegetable in both communes were in the low range and had statistically significant differences. In ND, mean iodine concentration in the soil was lower than in DH (2.63530 mg/kg vs 3.0360 mg/kg). In the water iodine mean concentration was lower in KT than in DH (0.00127 mg/kg vs 0.00173 mg/kg) and in vegetable 0.96100 mg/kg vs 1.15770 mg/kg respectively
A More evidence confirming the state of iodine deficie