OBJECTIVE To monitor and analyze the distribution and antibiotic resistance of common bacteria isolated from urine-tract infection patients in our hospital in recent two years and to provide new evidence for clinicians to choose the antibiotics. METHODS We used VITEK system to identify the bacteria,performed the drug-resistant test by K-B and analyzed the distribution and drug resistance of the isolated bacteria by WHONET 5.3 software. RESULTS A tatal of 1379 strains of bacteria were isolated from 2991 urine samples,most of which were Gram-negative bacteria.among which Escherichia coli was the most common.Enterococcus were the most common pathogen of gram-positive bacteria,especially for E.faecalis and E.faecium and fungi infection also increased.The resistance to antibiotics was quite different,manifesting multi-resistance.The detection rates of ESBLs-producing E.Coli,Klebsiella penumoniae and Proteus were 72.1%,69.9% and 34.2%,respectively. CONCLUSIONS It′s of great significance to summarize and analyze the distribution and biotic resistance of isolated bacteria in urine-tract infection to control resistant strains and indicate the choice of antibiotics in clinic.

To observe the effect of Weiyanxiao Granule (WG) in counteracting experimental gastric ulcer,acute lesion of gastric mucosa and to investigate its anti-inflammation and analgesic actions.Acute gastric ulcer models induced by stress or indomethacin, chronic gastric ulcer models induced by acetic acid and models with acute lesion of gastric mucosa induced by hydrochloride-ethanol or 0.2 mol?L -1 sodium hydroxide were used to observe the effect of WG in counteracting experimental gastric ulcer and acute lesion of gastric mucosa. Anti-inflammation action of WG was observed on mouse models with auricular swelling induced by dimethylbenzene, rat models with pedal swelling induced by white egg and rat models with granuloma induced by embedding tampon. Hot plate method and body-torsion test were used to observe the analgesic action of WG. As compared with the control group, WG 12.3?g?kg -1 and 24.6?g?kg -1 could decrease the ulcer index in rats with acute gastric ulcer (P