1.The Effects of Xiaofengzhiyang Particles Combined with Levocetirlzine in Treatment of Elderly Urticaria on Serum Levels of IL-2 and IgE
Zhanxiong XIE ; Tiesong WU ; Qiaohua PENG
Chinese Journal of Primary Medicine and Pharmacy 2012;(22):3371-3372
Objective To study the effects of Xiaofengzhiyang Particles and Levocetirizine on elderly urticaria and effects on the serum levels of IL-2 and IgE.Methods 96 elderly patients were randomly divided into two groups.The patients in study group were prescribed with Xiaofengzhiyang Particles and Levocetirizine.The patients in control group were prescribed with Levocetirizine,two weeks for a course.The curative effect and serum levels of IL-2 and IgE were observed after treatment.Results The complete cure rate of the study group was 69.6%,the control group was 52.5%.There was significant difference between the two groups(P<0.05).The serum levels of IL-2 and IgE were significantly decreased in study group(all P<0.01).Conclusion Xiaofengzhiyang Particles combined with Levocetirizine is effective in treating elderly urticaria,and the two drugs together could reduce the serum levels of IL-2 and IgE.
2.Effects of Piracetam on Superoxide Dismutase Activity and Malonaldehyde Content in Brain Tissues of D-galactose-induced Aging Rats
Zhanxiong XIE ; Jianwei WU ; Tiesong WU ; Donghong QIU ; Xiulian XIAO
China Pharmacy 2005;0(19):-
OBJECTIVE: To explore the effects of piracetam on superoxide dismutase(SOD) activity and malonaldehyde(MDA) content in brain tissues of D-galactose-induced ageing rats.METHODS: 30 SD rats were randomized to one of the 3 groups: blank control group(NS),model group(D-galactose+NS) and piracetam group(D-galactose+piracetam 432 mg?kg-1?d-1).All the rats were put to death at 90 days after medication,and the SOD activity and MDA content in brain tissues were determined.RESULTS: As compared with the blank control,the SOD activity decreased(P