OBJECTIVE:To observe the therapeutic effects of astragalus and angelica(A&A)composition in combination with losartan in treating diabetic nephropathy DN.METHODS:80patients with DN were randomly allocated into treatment and control group.A&A composition in combination with losartan were administered continuously for8wk in treatment group in addition to the conventional treatment with anti-hyperglycemics and hormone in control group.The indices of FPG,2hPG,GHbA 1c ,24hUAER,BUN,and Cr were observed before and after treatment,and the results were compared.RESULTS:90.0%、62.5%(P