With the continuous innovation and development in the field of interventional therapy, the complexity of surgery has been gradually increased, meanwhile, the psychological expectation from patients for a minimally invasive surgery has also become higher and higher. Patients expect not only to be safe to complete the surgery, but also to maintain the comfort during operation process. For ensuring these demands, anesthesia plays a key role. This paper aims to discuss the current situation, problems and development direction of anesthesia application in interventional surgeries in order to help promote the anesthesia management concepts in performing interventional procedures.

Objective: To provide references for the locating the third ventriculos tomy by measuring normal brain MRI data. Methods: Three hundreds normal brain MRI data were tagged and measured. The relevant reference data about third ventricle fistulization were obtained after statistics processing. Rosults: There were no statistical differences in the ratio of the distance before and after into the skull (BC / AC) in all age groups (P＞0.05). There were statistical differences in parameters of surgical approach-the distance of the middle line beside the incision (L),the depth inside the scalp (H) and the angle between the long axle of endoscope and the center sagittal plane (a) between ≤ 9-year--old and other age groups. The 95 percent confidence interval about parameters of surgical approach was obtained among all age groups. Conclusion: The results provide the reference of surgical treatment for the individual, enjoying the advantage of accuracy location and wide application.

In recent years, it has become increasingly apparent that noncoding RNAs (ncRNA) are of crucial importance for human cancer. The functional relevance of ncRNAs is particularly evident for microRNAs (miRNAs) and long noncoding RNAs (lncRNAs). miRNAs are endogenously expressed small RNA sequences that act as post-transcriptional regulators of gene expression and have been extensively studied for their roles in cancers, whereas lncRNAs are emerging as important players in the cancer paradigm in recent years. These noncoding genes are often aberrantly expressed in a variety of human cancers. However, the biological functions of most ncRNAs remain largely unknown. Recently, evidence has begun to accumulate describing how ncRNAs are dysregulated in cancer and cancer stem cells, a subset of cancer cells harboring self-renewal and differentiation capacities. These studies provide insight into the functional roles that ncRNAs play in tumor initiation, progression, and resistance to therapies, and they suggest ncRNAs as attractive therapeutic targets and potentially useful diagnostic tools.
Gene Expression Regulation, Neoplastic ; Humans ; MicroRNAs ; genetics ; metabolism ; Neoplasms ; genetics ; metabolism ; pathology ; therapy ; Neoplastic Stem Cells ; metabolism ; RNA, Long Noncoding ; genetics ; metabolism ; RNA, Untranslated ; genetics ; metabolism