1.Comparison of the effects of epinephrine and Vera Pammy coronary injection on the slow flow during myocardial infarction PCI
Chinese Journal of Biochemical Pharmaceutics 2017;37(6):240-242
Objective To explore the effect of intracoronary injection of epinephrine and Vera Pammy in patients with myocardial infarction with slow blood flowduring percutaneous coronary intervention (PCI).MethodsFrom January 2013 to October 2016, 68 patients with acute myocardial infarction with solw blood flow in Shanghai Jiading Hospital of Traditional Chinese Medicine during PCI were randomly divided into the epinephrine group(37 cases) and the verapamil group(31 cases).The two groups were treated with conventional drugs before surgery.The epinephrine group were injected into the coronary artery of 50 micrograms of epinephrine, the Vera Pammy group were injected into 200 micrograms of Vera Pammy.The coronary angiography, blood flow dynamics, as well as biochemical indexes in the two groups were observed.ResultsAfter the initial medicine, the ratio of TIMI flow grade 3 in the epinephrine group 81.80% was significantly higher than that in the Vera Pammy group 64.52%(P<0.05).The ratio of TIMI flow grade 3 after three times treatment, CTFC value after initial and 3 times treatment between the two groups have no significance.The blood pressure in the epinephrine group was (82.67±10.87) mmHg, which was significantly higher than that in the Vera Pammy group (70.46±9.54) mmHg(P<0.05).NT-proBNP, cTnT, LVEF in the two groups have no significance.hs-CRP in the epinephrine group was (7.68± 0.76) mg/L, which was significantly lower than that in the Vera Pammy group (9.25±1.05) mg/L.ConclusionThe effect is different which epinephrine and Vera Pammy were used in the patients with myocardial infarction with slow blood flowduring percutaneous coronary intervention.The use of epinephrine can significantly increase blood pressure, and the effect of initial medication is better.
2.Exploration of longitudinal clinical practice for professional degree postgraduate students in pediatric surgery
Chinese Journal of Medical Education Research 2015;(3):243-244,245
For professional degree graduate students, we improved the clinical teaching of pe-diatric surgery, on the basis of traditional forms of practice teaching, combining application of longitu-dinal cross major pediatric surgical practice. We had the student tracking patients from outpatient ser-vice and by going through the process of after examination, treatment, follow-up, and summarizing. students learnt all characteristics of the disease, expended their knowledge and grasped the correct, novel clinical thinking of diagnosis and treatment. The implementation of these measures obtained sat-isfactory teaching effect.
3.High risk factors for BK virus viremia in recipients following kidney transplantation
Chinese Journal of Tissue Engineering Research 2007;0(31):-
BACKGROUND: One major reason for transplanted kidney failure is BK virus (BKV) associated nephropathy, which leads to renal inadequacy and ureteral obstruction. OBJECTIVE: To identify the incidence of BKV viremia in kidney transplant recipients, as well as to analyze the risk factors of BKV infection. DESIGN, TIME AND SETTING: A retrospective case analysis was performed at the Department of Urology, Affiliated Beijing Friendship Hospital of Capital Medical University from September 2001 to December 2007. PARTICIPANTS: One hundred and twenty-one renal transplant patients, and 20 renal failure patients, who underwent hemodialysis were served as control group. METHODS: The viral load in plasma was quantified with a real-time PCR method. The recipients were divided into the PV+ group (BKV DNA positive blood samples) and PV- group (BKV DNA negative in blood samples) according to the detection outcomes. The gender, age, cold ischemia time, immunosuppressive agent, donor type and other clinical parameters were compared between 2 groups. MAIN OUTCOME MEASURES: Logistic regression was performed to determine risk factors for BKV infection. RESULTS: The incidence rate of BKV viremia accounted for 24.7% (30/121) of kidney recipients, which was higher than the control group (1/20), the difference between them was significant (P = 0.03). Logistic regression found that cold ischemia time (RR 3.34, 95% CI 2.76-5.60) and cadaver donation (RR 2.19, 95% CI 1.32-3.97) were significantly related to BKV viremia. However, ages of recipients, time of collecting samples, and intravenous glucocorticoid therapy was independence to BKV viremia. CONCLUSION: Kidney recipients are the high risk population who are susceptive to BKV infection. Cold ischemia time and cadaver donation may be the risk factors of BKV viremia.
4.Design and application of hospital material management system
Chinese Medical Equipment Journal 1993;0(06):-
In order to improve the scientificity and rationality of materiel management,we developed the materiel management system and realized the computerizing of material management. This system can solve all problems in material computerizing which occur during the process from the material application to its abandonment. Aiming at solving disadvantages in human management,the utilization of this system will greatly reduce the staff's work load,enhance the working efficiency and make the material management standardized.
5.Interventional Therapy for Deep Venous Thrombosis in the Lower Limbs
Chinese Journal of Minimally Invasive Surgery 2005;0(12):-
Objective To investigate the clinical effectiveness of interventional therapy for deep venous thrombosis(DVT) in the lower limbs.Methods A total of 38 patients with DVT were treated by intravenous thrombolysis;12 of them received percutaneous transluminal balloon angioplasty and intravascular stenting after the thrombolysis.According the evaluation criteria of our hospital,the outcomes of the patients were classified as cure(angiography showed complete lysis of the thrombus and smooth venous wall),markedly improved(the deep vein was patent with intravascular mural thrombi,the inner radius was reduced by less than 1/3),improved(angiography showed residual thrombi in the deep vein,and the inner radius was reduced by more than 1/3),and failure(the vein was still obstructed).Results After the treatments,cure was achieved in 22 patients,markedly improved in 14,and improved in 2.No severe complications occurred during the operations.Thirty-four of the patients were followed up for 3-24 months(3-6 months in 7 cases,7-12 months in 12,and 13-24 months in 15).Two patients had recurrence during the follow-up and were cured by intravenous thrombolysis.Conclusion Interventional therapy is continent,effective,and safe for DVT.
6.Recognition and Interaction of Innate Immune Receptors
Progress in Biochemistry and Biophysics 2006;0(02):-
NKR and TLR are most important receptor superfamilies in innate immunity and act as first line of host defense against infection. Those receptors exert peculiar recognition mechanisms to sense danger signals and distinguish infectious nonself from noninfectious self. More importantly, they coordinate and regulate each other and therefore play major roles in initiation of innate immunity and also help to direct adaptive immune responses. The importance of recognition and interaction of those receptors are highlighted. The precise mechanisms can be harnessed to aid the rational design of therapy against infection, inflammation, cancer or autoimmune diseases.
7.Research on information management of medical equipment
China Medical Equipment 2016;(2):128-130,131
Objective:To explore the influence of information technology on the management of medical equipment.Methods: To develop the protocols how to improve the management level of medical equipment planning, procurement, installation, performance evaluation, warehouse management, measurement, quality control, and maintenance, etc.Results: The promotion of information technology can promote the medical equipment management to achieve closed-loop control, open and transparent, efficiency improvement, module management, massive data analysis, etc.Conclusion: Information management can promote the relevant departments of the hospital medical equipment to improve the level of cooperation, to achieve functional integration, combination of medicine and engineering, be better for clinical services.
8.Investigation and Analysis on the Learning Motivation and Learning Interest in Topographic Anatomy
Chinese Journal of Medical Education Research 2003;0(02):-
Good learning motivation can improve the learning interest and learning activity,enable students to form good learning habits,and achieve satisfactory effects.This research is to find out the problems of learning motivation and interest in the teaching of topographic anatomy,and provide some psychological evidences for the reform of topographic anatomy teaching.
10.A clinical observation of heart rate turbulence of diabetes
Chinese Journal of Diabetes 2009;17(12):933-934
Objective To discuss the significance and alteration of heart rate turbulence (HRT) of diabetics with ventricular premature beats of coronary heart disease (CHD). Methods 107 patients were chosen and divided into DM group(n=30), CHD group (n=32)and normal group(n=45).The turbulence onset(TO)and turbulence slope(TS) were calculated and analyzed. Results For the diabetics with ventricular premature beats, TO value was higher and TS value was lower than the normal group(all P<0.05).The value of TO and TS of the diabetics with ventricular premature beats were similar to those of CHD(P>0.05). Conclusions HRT can be used to estimate the integrality and stability of cardiac autonomic nerve function for the diabetics and it is an important factor for diagnosis.