We proposed a multi-resolution-wavelet-transform based method to extract brainstem auditory evoked potential (BAEP) from the background noise and then to identify its characteristics correctly. Firstly we discussed the mother wavelet and wavelet transform algorithm and proved that bi-orthogonal wavelet bior5. 5 and stationary discrete wavelet transform (SWT) were more suitable for BAEP signals. The correlation analysis of D6 scale wavelet coefficients between single trails and the ensemble average of all trails showed that the trails with good correlation (> 0. 4) had higher signal-to-noise ratio, so that we could get a clear BAEP from a few trails by an average and wavelet filter method. Finally, we used this method to select desirable trails, extracted BAEP from every 10 trails and calculated the I-V inter-waves' latency. The results showed that this strategy of trail selection was efficient. This method can not only achieve better de-noising effect, but also greatly reduce the stimulation time needed as well.
Algorithms ; Brain Mapping ; Evoked Potentials, Auditory, Brain Stem ; Humans ; Wavelet Analysis

Autophagy ; Cervical Cord ; injuries ; Humans ; Magnetic Resonance Imaging ; Spinal Cord Injuries ; complications ; diagnosis ; pathology

Cytological Techniques ; methods ; Diagnosis, Computer-Assisted ; Female ; Humans ; Vaginal Smears ; methods

Alzheimer′s disease (AD) is a degenerative neurodegenerative disease of the central nervous system. The disease is concealed. Patients often experienced several years or even more than ten years of course evolution from the beginning of pathological changes to clinical symptoms. Once entering the stage of dementia, there is no ideal drug to reverse the disease. In order to improve the efficiency of early diagnosis, the research on early biomarkers of the disease has become a hot topic in recent years. In addition to the Aβ and tau, microRNAs have been discovered as potential biomarkers of AD.

Objective:To analyze the influencing factors of investment management of hospital intangible assets,so as to provide countermeasures for establishing and optimizing the investment management system of hospital intangible assets.Methods: Taking hospital reputation as an example,we analyzed its role in the investment management of hospital intangible assets and the maintenance of hospital reputation in an economic perspective using Shapiro model and game theory.Results: The factors,such as the blueprint of hospital,efficiency of medical quality information transmission,and cost variance,all influenced the reputation of hospital.Conclusion: In the health care field,stable property right system should be established and market information agents should be cultivated.The administrative actions of involved departments should abide by the related regulation and the running system of hospitals should be optimized.

OBJECTIVE:To raise the price fixing of drugs to a scientific and reasonable level.METHODS:From the view of the whole society,the economic efficiency of newly-developed drugs and original drugs was compared with cost-effec?tiveness analysis.RESULTS&CONCLUSION:Through comparison,the price ranges with economic efficiency of newly-de?veloped drugs would be obtained,which could guide the price fixing.

OBJECTIVE:Using the result of pharmacoeconomic evaluation to instruct the management of drug prices.ME_ THODS:Establishing a reference price and combining economic benefit to decide the price of a drug.RESULTS&CONCLU_ SION:According to the rational value scope,the prices of new drugs can be fixed.A reasonable and timely adjustment of the price can be made.

Objective To study the reconstruction and secretory function of the grafts after adrenal transplantation using fetal rats as donors.Methods Thirty adult SD rats randomly received sham operation(group A),excision of bilateral adrenals(groups B,C,D and E),and additionally adrenal transplantation in groups C,D and E using fetal rats aged 16,18 and 20 days respectively as donors.Results The weight of group A got down to the lowest at the 3rd week,and restored to the preoperation level at the 4th week after sham operation.The weight of group B gradually rose up within 4 weeks.The weight of groups C and D rose up in the first 2 weeks,then down.The weight of group E rose slowly within the first 3 weeks,then down.The serum level of corticosterone decreased sharply in group B after operation,while that of groups C,D and E went down obviously in the first 2 weeks,then up,but that in group C was significantly lower than that in groups D and E.Microscopically,we found the capsule of allografts thicken and underneath many proliferative cells and well-constructed glomerular and fascicular zone 4 weeks after operation.Conclusion After transplantation,the fetal adrenal could survive and reconstruct well,and its secretory function gets better gradually.The graft from the elder donor is better than that from the younger in reconstruction and secretory function,but shows no obvious difference in immunological rejection.

There is a trackphenomenon in the development of hypertension and pediatric hypertension has an important predictive value for adult hypertension. However pediatric hypertension is not typical and normal blood pressure is associated with age,sex and height. The blood pressure level,clinical presentation and complication rates of secondary pediatric hypertension are higher than primary pediatric hypertension. So secondary pediatric hypertension could get timely treatment compared to primary pediatric hypertension. This paper focus on the clinical presentation and diagnosis criterion of pediatric hypertension and provide a reference for the pediatrician.

The core problem of current rural health services is a governance problem, that is, how the basic rural health resources can be used more effectively. Based on the study of history and reality, this paper suggests that in the existing “government-market” framework, the village is the third perspective worthy of consideration. Inside the village community, the trust, network and cooperation between people which were based on the traditional rural acquaintances society capital and the institutional resources in the organizations at the primary level will be able to in-crease the degree of organization, thereby reducing the transaction costs between the government or the market and rural residents. The village power will be able to better take advantage of government and market mechanisms, and thus solve the problem of rural health resource utilization more effectively.