1.Subacute thyroiditis as seen initially in ENT department--a report of 30 cases.
Journal of Huazhong University of Science and Technology (Medical Sciences) 2002;22(1):82-3
To assess the pharyngeal presentations and the diagnostic value of thyroid SPECT and thyroid fine needle aspiratory biopsy (FNAB) in subacute thyroiditis (SAT) as seen initially in ENT department, 30 patients, during the course of SAT, were examined for pharyngeal symptoms and tested for serum T3, T4 level. The thyroid SPECT imaging or thyroid FNAB were performed. Our results showed that, of the 30 patients, 21 had sore throat of various degrees, and 9 had abnormal sensation of throat. Six were diagnosed as having SAT by only SPECT, in the remaining 24, the final diagnoses was established by SPECT combined with FNAB. Two of them were finally diagnosed as having SAT by trial treatment with oral prednisone. It is concluded that sore throat and abnormal sensation of pharynx are the important presentations of SAT, and thyroid SPECT imaging and thyroid FNAB are valuable in diagnosing SAT.
Diagnosis, Differential
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Pharyngeal Diseases/diagnosis
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Pharyngitis/diagnosis
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Thyroid Gland/*radionuclide imaging
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Thyroiditis, Subacute/*diagnosis
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Thyroiditis, Subacute/radionuclide imaging
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Tomography, Emission-Computed, Single-Photon
2.High Prevalence of Thyroid Disease and Role of Salivary Gland Scintigraphy in Patients with Xerostomia
Ji hoon JUNG ; Chang Hee LEE ; Seung Hyun SON ; Ju Hye JEONG ; Shin Young JEONG ; Sang Woo LEE ; Jaetae LEE ; Byeong Cheol AHN
Nuclear Medicine and Molecular Imaging 2017;51(2):169-177
PURPOSE: Although Sjögren's syndrome (SS) is the most common disease causing xerostomia, autoimmune thyroid diseases can also affect the salivary glands. The aim of our study was to estimate the prevalence of thyroid diseases (TD) in subjects with symptoms of xerostomia and evaluate the efficacy of salivary gland scintigraphy (SGS) in the detection of TD in patients with SS and without SS.METHODS: We retrospectively reviewed the SGS findings of 173 subjects (men:women, 29:144) with symptoms of xerostomia. Ejection fractions (EF) in the parotid and submandibular glands were calculated. Thyroid disease was diagnosed on the basis of the results of the visual assessment of tracer uptake in the thyroid gland on SGS images as well as serological thyroid function tests.RESULTS: Based on the American-European Criteria, 94 patients were diagnosed with SS. Hashimoto's thyroiditis was diagnosed in 63 patients, subacute thyroiditis in 23, subclinical hypothyroidism in five, and Graves' disease in one. There were significant differences in the EF values of the parotid and submandibular glands between patients with TD and those with undetermined diagnoses.CONCLUSIONS: More than half of patients with xerostomia exhibited TD. Thyroid assessment by SGS is feasible, and SGS appears to be useful for the patients with xerostomia caused by TD. SGS may be the first imaging modality capable of evaluating both salivary gland function and thyroid gland status in patients with xerostomia. This strategy would make the requirement for additional workup for thyroid disease.
Diagnosis
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Graves Disease
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Humans
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Hypothyroidism
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Prevalence
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Radionuclide Imaging
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Retrospective Studies
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Salivary Glands
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Submandibular Gland
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Thyroid Diseases
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Thyroid Function Tests
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Thyroid Gland
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Thyroiditis
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Thyroiditis, Subacute
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Xerostomia