A study on the healthy voluntary adults without acute or chronic thyroid diseases, with ages of 21-48 who lived in Hanoi, Hai phong and HoChi Minh city has shown that there were no differences of total T3, T4 and FT3, FT4, TSH in the morning, noon and afternoon and there were no significant difference of these between men and women in each region and between regions.
Hormones ; Receptors, Thyrotropin ; Thyroid Hormones

Objective: To present a case of a double ectopic thyroid gland in a 10-year old boy and discuss the pros and cons of the different management options that were available. Methods: Design: Case Report. Setting: Tertiary Hospital in Metro Manila. Subject: One (1). Results: A 10-year-old boy presented with hoarseness and easy fatigability for 6 years. Rigid endoscopy and CT scan showed an infraglottic mass originating from the anterior tracheal wall causing obstruction. Biopsy revealed thyroid tissue with atypia. Thyroid scintigraphy showed uptake in the submental and midline anterior neck. Thyroid hormone levels were consistent with hypothyroidism. Levothyroxine returned hormone levels to normal and resulted in complete regression of the mass with no symptoms of dyspnea, stridor or bleeding. Conclusion The management of ectopic thyroid presents a challenge as there are no guidelines for optimal treatment. Thyroid hormone insufficiency is a frequent occurrence, and emphasis must be given to its monitoring. Surgery in a critical airway lesion such as this may be reserved for cases where the patient experiences dyspnea and stridor or lack of response to thyroid hormone treatment.
Thyroid Dysgenesis ; Thyroid Hormones ; Thyroxine

A study on 352 patients with the first consultation was diagnosed Basedow in the Army central hospital 108 during 1996- 1997. The results have shown that age, models of change of T3, T4 in patients with Basedow and the comparison of T3, T4 with the clinical symptoms played an important indicators to monitor the progress of the disease, evaluation of normalization of thyroid and indication for operation.
Thyroid Hormones ; Thyrotropin

Objectives: Daily levothyroxine is the treatment of choice and standard of care in hypothyroidism, sufficient to restore thyroid stimulating hormone (TSH) to normal range. For many patients, daily lifelong therapy is required, making adherence a major issue. In such cases, weekly replacement may be a suitable alternative to improve adherence. In this study, we aimed to determine the efficacy and safety of weekly levothyroxine replacement among adults with hypothyroidism. Methodology: Electronic databases were searched. Two reviewers (HCC and RBL) independently screened the abstracts, reviewed full-text papers, critically appraised the quality of included studies using PRISMA guidelines. Meta-analysis was performed using the random-effects model. The primary outcome is the difference in serum TSH levels between weekly and daily administration, while secondary outcomes included adverse events and symptoms of hypothyroidism. Results: The primary outcome is the difference in serum TSH levels between weekly and daily administration. Secondary outcomes included adverse events and clinical symptoms. The study included two randomized trials (n=109) in the primary analysis. The difference in TSH levels was 1.78 mIU/mL higher [(95% confidence interval (CI): 1.28 to 2.28, p<0.00001] at 6 weeks and 1.22 mIU/mL higher (95% CI: 0.76 to 1.67, p<0.00001) at 12 weeks for the weekly regimen. There was no significant heterogeneity between the two groups. There was no significant difference in hypothyroid symptoms and adverse events before and after levothyroxine treatment within each group. Conclusions Weekly levothyroxine resulted in less suppression and higher mean serum TSH levels, while still remaining within the normal reference range. It may be a suitable alternative for non-adherent patients. However, larger randomized trials with longer duration of follow-up are needed to firmly establish its role.
Hypothyroidism ; Thyroxine ; Thyroid Hormones

This study relates to stability of the hormones in the thyroid powder of the pig, dried by lyophilizating; vacuum drying at the temperature of 50oC, and by normal drying at the temperature 70oC. Using high performance liquid chromatography (HPLC) to measure thyroid hormone concentration in the powder of thyroid before and after release test at the temperature of 40±2oC and the relative humidity of 75±5% for 3 months. The result is: The hormone of the thyroid powder, dried at 70oC, have got required stability and it is less than the one of the thyroid powder dried by lyophilizating or vacuum drying.
Hormones ; Vacuum ; Thyroid Hormones ; Chromatography, Liquid

No abstract available.
Depression* ; Prolactin* ; Thyroid Gland* ; Thyroid Hormones*

Studying the result of multi-approach combinations: surgery, radioactive iodine (131-I) and hormones for treatment of differentiated thyroid cancer at Bach Mai hospital. The result showed that: surgery was basic method to remove total thyroid gland, nodes, and metastasis. Radioactive iodine 131-I was supplement therapy to destroy thyroid remnant tissue after surgery. Hormone therapy using T3 or T4 make the patients became in euthroidism status and inhibit TSH secretion. The recurrence and metastases can be detected by serum Tg value determination and 131-I systemic scintiography. Therefore the patient must be followed -up every 6 months in the first two years, and then once a year or every two years
Thyroid Neoplasms ; Therapeutics ; Hormones ; Iodine

T3, T4, TSH concentrations in the blood of people without endemic goiter living in the island endemic goiter area (A area) were not changed in comparing with health people in Ha Noi (B area). But T3, TSH concentrations increased and T4 decreased in people with and without goiter in A area to compare with healthy people in B area. These above changes were clear in people with goiter in the A area.
Thyroid Hormones ; Goiter, Endemic ; Thyrotropin

A descriptive surveillance study was carried out at Tien Giang province in 6299 people, 30 clusters has showed that Goitre rate was 24,4% in adult and 12,8% in children with iodine trace in urine 4 mcg/dl. The authors recommended the universal use of iodinized salt.
Thyroid Hormones ; Goiter, Endemic ; Thyrotropin

352 patients were firstly diagnosed as basedow in the Army Central hospital 108 during 1996- 1997 participated to a study. The patients were classified according to the age groups, the types of changing the T3 and T4. The comparison of the level of T3 and T4 with the clinical diagnosis has shown that the level of T3 and T4 were an important criteria to monitor the progress of the disease, evaluate the normalization of the thyroid and help the indication for surgery.
Thyroid Hormones ; Euthyroid Sick Syndromes