1.Evaluation of antibiotic choices in the treatment of septicemia at Bach Mai Hospital
Pharmaceutical Journal 2005;347(3):28-30
Study on the pathogens of septicemia in order to choose appropriately antibiotics in the treatment. Subjects were 138 septicemia patients admitted to Institute of Infectious and Tropical Diseases from June 2001 to May 2002. All patients were taken their blood samples to isolated and culture bacteria during they had high fevers or before taking antibiotics. Some pathogenous bacteria were isolated and identified in 20.3% patients. The most common species were S. aureus (accounted for 42.4%), followed by Enterobacteriaceae (28.8%)
Anti-Bacterial Agents
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Therapeutics
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Sepsis
2.Research on susceptibility of mosquito Ae. aegypti to insecticides in some Northern provinces between 2001 and 2004
Journal of Preventive Medicine 2005;15(5):117-122
Aedes aegypti mosquitoes had been collected at field of some Northern provinces between 2001 and 2004 for studies of their susceptibility to insecticides. It was seen that: all of tested mosquitoes dropped immediately 100% and 100% killed after 24 hours. The results showed that all tested mosquitoes were highly susceptible to insecticides, such as permethrin, lambda cyhalothrin, and malathion from 2001-2004 in Northern region. The provinces participate in the test was up fro 5-7. Using the insecticides to kill Aedes aegypti by ULV spraying was effective in Northern provinces in Vietnam. It is adviced to send mosquitoes and lavae in June and July when the density of mosquitoes and lavae is high. Therefore, expanding studies to other provinces throughout the country to identify susceptibility of Aedes aegypti to insecticides is very necessary for Dengue Hemorrhagic Fever vector control.
Culicidae
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Insecticides
3.Selection of rotavirus strains G1 by doning and passaging on cell culture
Journal of Preventive Medicine 2005;15(5):133-137
A single B17.3 strain was selected from 45 Rotavirus strains by the method of CDC-Atlanta, USA - cloning and adaptation assay on cell culture. The strain is one of seed candidates for Rota vaccine production in Vietnam.
Rotavirus
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Cells
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Cell Culture Techniques
4.Sequencing VP4, VP7, NSP1, NSP4 genes of human Rotavirus strain G1P8
Journal of Preventive Medicine 2005;15(6):27-32
Rotavirus is the main cause of acute viral gastroenteritis in children under 5 years old. The study is to sequence nucleotides and amino acids of VP4, VP7, NSP1, and NSP4 genes of 5 passages of human rotavirus strain G1P8. The number of nucleotide mutations of VP4, VP7, NSP4 genes occuring among the passages were 3, 1, and 3, respectively. All these mutations resulted in changes in amino acid composition. No mutation was found in NSP1 gene.
Rotavirus
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Human
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Genes
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Child
5.The postzosterian pain treatment: A comparison between amitriptyline and Di-antalvic
Journal Ho Chi Minh Medical 2003;7(2):104-109
Prospective clinical trial on two groups of patients: one treated with amitryptyline and the other with diantalvic. Results: At the beginning of study, no difference in the severity of pain in both groups. Group 1 had more effective to control pain than group 2. After one week of treatment, group 1 had one case (3.3%) while group 2 had 15 cases (35.7%) didn’t have any improvement. Amitriptyline had more advantages that Diantalvic to treat the postzosterian pain
Pain
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Amitriptyline
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Drug Combinations
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Herpes Zoster
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Therapeutics
;
drugs
6.Plasma homocystein in type 2 diabetes patients
Journal Ho Chi Minh Medical 2003;7(3):155-160
At the University Medical Center, from August, 2001 to August, 2002, total plasma Homocystein of 31 controls and 50 type 2 diabetes was measured. The mean value of homocystein concentrations in type 2 diabetes is 11.77 4.45 M/l (mean SD). This is significantly higher than the value of controls (9.93 2.93 M/l (mean SD)
Homocysteine
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Diabetes Mellitus, Type 2
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disease
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Plasma
7.The mobility rehabilitation situation for cerebral palsy persons in Ha Tay provine
Journal of Practical Medicine 2004;471(1):23-25
The study was conducted on 238 cerabral palsy palsy patients aged 0-68 years in 19 commune of Ha Tay province. In 41,2% of patients mobility function rehabilited by common methods, among them, 82% by oriental traditional medicine, 13% by western medicine method and 5% by combined methods, 24% by special methods. Provincial hospital played a very modeste role in functional rehabilitation from cerebral palsy and in Hospital at district level, the role was nearly none.
Cerebral Palsy/rehabilitation
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Rehabilitation
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Epimiology
8.To compare clinical, biological and histological features of primary nephrotic syndrome and nephrotic syndrome due to systemic lupus erythematosus in adults
Journal of Medical Research 2005;33(1):110-116
Study on all in-patients treated at Kidney Department of Bach Mai Hospital from 2000 to 2002, which divided into 2 groups: group 1 included 38 patients with lupus nephritis and nephrotic syndrome, group 2 included 45 patients with primary nephrotic syndrome (NS). Results: most of primary NS occurred before the age of 50 years old (95.6%), there was no difference between male and female. NS due to systemic lupus erythematosus (SLE) had multiple clinical signs and was more severe than in primary NS. The prevalence of renal impairment in both primary and secondary NS was high (44.4% and 55.3%, respectively). The serum protein concentration in primary NS was significant lower than secondary NS (p<0.01). Nevertheless, serum cholesterol, HDL-C, LDL-C concentrations in primary NS were significant higher than secondary NS (p<0.01). In primary NS, the rate of minimal change glomerulonephritis was highest (51.1%), but in secondary NS, mesangial proliferative glomerulonephritis accounted for highest rate (63.2%). In type IV in secondary NS due to SLE, there were symptoms of hypertension, renal failure, hemorrhage and the histological damages were more severe than in other types (p<0.05). Histological lesions in secondary membrane and mesangial proliferative glomerulonephritis due to SLE were more severe than primary diseases.
Nephrotic Syndrome, Lupus Erythematosus, Systemic, Adult, Diagnosis
9.Evaluation on chosen antibiotics in treatment for bacterial infection in Bach Mai Hospital
Pharmaceutical Journal 2005;0(5):28-31
138 cases with bacterial septicemia in Bach Mai Hospital were divided into two groups. The first group (n=51, 36.9%) was given single treatment (one antibiotic). The second group (n=87, 63.1%) was given combination treatment (two antibiotics). Due to the rate of cultured negative blood is high (about 70%), so the rate of initial treatment using antibiotic combination (63%) is higher than single antibiotic treatment (37%). Antibiotic groups used in combination treatment is aminosid antibiotics, in which amikacin is selected the most (27/37 cases, 72.9%). Third generation cephalosporin group makes the highest rate in single treatment (49%) as well as in combination treatment (58.7%). Quinolones, pefloxacin group used almost as initial method (single as well as in combination)
Anti-Bacterial Agents
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Therapeutics
10.Fulfilment of the RT - PCR quantitative and application of the quantitation of the CK 20 gen in the peripheric blood of the colon cancer
Journal of Vietnamese Medicine 2004;295(2):27-30
The authors carried out of the study on ARN message extrait from the peripheric blood of the 20 patients diagnosed to have colon cancer and 13 control healthy persons by RT - PCR quantitative with marker CK 20. The obtained results are as follows: The technique have been fulfilled; The CK 20 in the patients and the healthy person is not significant different
Colonic Neoplasms
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Blood
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RNA