1.Inhibition of human cancer cell lines by recombinant trichobakin
Journal of Vietnamese Medicine 2003;284(5):26-30
Recombinant trichobakin (TBK) has been subjected to study its capacity in inhibiting the growth of three lines of human cancer cell - epidermoid carcinoma of the mouth (KB), rabdomyo sarcoma (RD-26) and myelo sarcoma (2/0-Ag-14), it has been shown that TBK has inhibited the cancer cells. Myeloma sarcoma cells were inhibited by TBK at the lowest dose (ID50 2.55 microgram/ml). For RD-26 and KB cell lines, ID50 = 7.27microgram and 10.5 microgram/ml respectively. After 2 year preservation, protein recombinant contains almost the same inhibition activity from its original one
Neoplasms
;
Therapeutics
;
drugs
2.The dysfunction of left ventricular diastolic in type 2 diabete patient
Journal of Practical Medicine 2003;463(10):29-30
Study on 66 men with type 2 diabetic at Military Hospital 108 and 103 healthy persons (with similar age, BIM, HATTh, HATTr, frequence of heart). Results: In type 2 diabetic group, A-C distance front of bicuspid valve extend, slash volume significant reducing compared with control group. Left autrial size, intraventricular septum wall thickness, ventricular wall thickness, left ventricular mass index (LVMI) significant changing compared with control group. Non THA diabetic group include 3 patients ventricular hypertrophy (LVMI > 131 g/m2), in control group hasn’t any patients. In VT Ia diabetic group, VTIe/VTIa rate reduce, DT time lengthen significantly compare with control group
Diabetes Mellitus, Type 2
;
Ventricular Dysfunction, Left
;
Ventricular Function, Left
3.Some observation on the incidence of cerebral paralysis in HaTayprovince
Journal of Practical Medicine 2003;463(10):54-55
The incidence of cerabral paralysis in Ha Tay Province is counted by 2 ways: the incidence on lower 5 years old children an “the incidence on newborn”. The incidence on children who were borned from 1/1/1994 to 31/12/1997 live to 5 years old is 3.01/1000 in which the highest years (1996) is 4.69/1000 and the lowest years (1994) is 1.97/1000. Rate of getting cerebral paralysis take 1/3 new cases at the same age group. Rate of death at ≤ 5 age take 1% nearly (112/1620). The rate include death in newborn. Number of ≤ 5 children death due to cerabral paralysis take 11% death cases total. New suffer cerabral paralysis rate from 1994-1997 is 4,18/1000 alive children
Paralysis
;
Brain Ischemia
;
epidemiology
4.Dosage of nimesulide in tablets by second derivative UV spectrum method
Pharmaceutical Journal 2003;234(4):16-18
Used second order derivative UV (200-500nm) spectrum to determine the quantity of nimesulid in tablets without through process of deal with sample. Assess linear interval, limit of detection, limit of determine the quantity between level of nimesulid solution and value of second order derivative in interval of study level, degree of accuracy of the method and result of determine the quantity of nimesulid. The result showed that: process of quantitative nimesulid was built. The method was accurate, sensitive, precise, and reproducible and could be applied directly and easily to the pharmaceutical preparations.
Spectrum Analysis
;
Pharmaceutical Preparations
;
Adjuvants, Pharmaceutic
;
tablets
5.The results of Denwer and Raven test in 238 cerebral palsy patients
Journal of Practical Medicine 2003;466(11):21-24
The results of Danver test and Raven test on 238 > 6 years old of age children with cerebral palsy in HaTay province were assessed. With Ravent test, only 2% among them had not mental retardation, but 98% had mental retardation in various levels. Among the subjects of floppy form of cerebral palsy there is not any case of normal mental level, but a light level of retardation. With Denver test, 26% of cerebral palsy children had got normal development in comparing with the other. But there are different levels of retardation in various domains, 97% of cerebral palsy children got retardation in mobility domain, 85% in individual and social domain, 61% in adaptative mobility and 53.7% in laguage domain
Cerebral Palsy
;
Brain
;
Brain Diseases
6.Some comments about sex and average age of cerebral palsy
Journal of Practical Medicine 2003;466(11):54-57
In studying 155.633 subjects living in Ha Tay, among them 238 suffered from cerebral palsy, 54% of cases are male, 46% female. Gender ratio male/female: 1.16, varying with age groups. The highest 1.9 in under 10 years of age group. The lowest 0.2 of > 50 years of age group. Cerebral palsy patients mean age are 18.2 versus 28.3 of normal population in this survey. Average age and maximal age of cerebral palsy patients in Ha Tay are lower than those of the patients in developed countries
Cerebral Palsy
;
Brain
;
Brain Diseases
7.Obstetric ultrasound scanning in urban Vietnam: Is it being over used?
Journal of Practical Medicine 2005;530(11):34-37
The study was conducted at Hanoi Obstetrical and Gynecological Hospital, combining quantitative and qualitative research methods. Results: the study showed that there was a tendency for pregnant women to over-use ultrasound scanning. The reasons for this included women’s perceptions of the usefulness of ultrasound scanning, their serious worries for the fetus, as well as the effects of the market economy on this health service. Over-use of obstetrical ultrasound scanning was not only related to the perception, demands and psychology of pregnant women, but also to socio-economic changes associated with the economic reforms and the liberalization of the health care system.
Ultrasonography
;
Epidemiology
8.Antimosquito olyset net used for Dengue hemorrhagic control in some North provinces
Journal of Practical Medicine 2003;442(2):98-101
Olyset net sunk with 2% permethrin was used in Hai Duong, Hai Phong, Thai Binh. The rate of density index and house index were decreased from 0.23 and 23.3 to zero and persisted by 9 months. Breteau index and larve-house index was also decresed from 8.3 and 6.7 to zero. Olyset net showed its effect on Aedes aegypti and in various mosquitos and insects
Dengue Hemorrhagic Fever
;
Mosquito Control
;
Disease
;
epidemiology
9.Clinicopathological study of invasive cervical carcinoma
Journal of Vietnamese Medicine 2002;269(2):1-8
The clinical and histopathological characteristics were studied on 384 cases with invasive cervical cancer (ICC). The results have shown that high rate of ICC was found in the age range from 40 to 49 years. Hemorrhagic symptom is in highest rate (86.46%). Stage II A patient rate is high (30.99%) and the patients of stage II A and IIB are of more than haft of the patients (53.91%). The great majority of cases is nonkeratinisant large cell carcinoma (61.98%) and had strong stromal inflammatory reactions. The difference of stroma inflammatory reactions of histological types has statistical significance (p=0.014). Immunohistochemical stain for AE 1/AE 3 were positive in 96.29% of case and helpul in the identification of tumor cell differentiation.
Carcinoma
;
Uterine Cervical Neoplasms
10.Immunohistochemical and ultrastructural study on the invasive cervical carcinoma
Journal of Vietnamese Medicine 2002;277(10):6-9
The aim of this study is to identify some immunohistochemical, and ultrastructural characteristics of invasive cervical cancer (ICC). Twenty seven cases were immunohistochemically examined for the presence of cytokeratin AE1/AE3, Her-2/neu, CD20 and CD45. Ultrastructural study was carried out on 10 cases. Results: Immunohistochemical stains for AE1/AE3 were positive in 92.29% of cases and very helpful in the identification of tumor cell differentiation. The majority of infiltrating lymphocytes was T-cells. Her 2/neu oncogene expression was high. Ultrastructurally, the cells showed a scantly cytoplasm, decrease of cytoplasmic organelles, decrease of intercellular adhesion and apparition of microvillosities in adenocarcinoma. The presence of HPV virus-like particles was found in two cases. The crystals were revealed in the eosinophilic leukocyte granules.
Carcinoma
;
Uterine Cervical Neoplasms
;
ultrastructure