Vietnamese ginseng leaves had the effect on the central nervous system, shortening pentobarbital-induced sleeping time in smaller doses and lengthening pentobarbital- induced sleeping time in larger doses. Vietnamese ginseng leaves extract (600, 1200mg/kg p.o) and its total saponin (200mg/kg p.o) significantly recovered the stress-induced decrease in pentobarbital sleep to the normal level. In the other hand, Vietnamese ginseng leaves extract and its total saponin have the invigoration and antioxidant effects
Plants, medicinal ; Pharmaceutical Preparations ; Panax

Both ethanol extracts of the bark and leaves of Schefflera elliptica (Blume) Harms (Araliaceae) showed antistress effect on mice at the oral doses of 158 and 167 mg/kg body weight, respectively. The bark proved to be more effective than the leaves, and their efficacity increased with the doses. Both extracts possessed in vitro antioxidant activity at the concentrations of 50-100 mcg/ml, the bark also being more effective than the leaves. The total saponin extract of the bark exhibited antioxidant effects at the levels of 5-25 mcg/ml. So, saponins might be the chemical constituents determining the antioxidant activity.
Plants ; Biochemistry ; Araliaceae ; Therapeutics

Study on 5409 female employees who were directly taking part in agricultural production in 3 regions: the North 1794 persons; the Central 1805 persons; the South 1810 persons. 1218 persons were randomized for clinical examination: the North 418 persons, the Central 392 persons and the South 408 persons. 293/1218 persons were selected for examination of worm eggs. Results: the rate of gynecological disease was 19-23%; dermatological disease in the North was rate of 20.11%, the Central 23.97%, the South 37.64%; Muscular disease was 15.5-18.5%. The infection rate of ascaris was 78.5%, the negative rate was only 8.5%. The physical indexes of female employees were in normal limitation of Vietnamese people.
Health ; Agricultural Workers' Diseases

Background: Severe penetrating eye injury is a common emergency in ophthalmology. Objectives: The evaluation results and complications following vitrectomy in severe penetrating injury in children. Subjects and method: This study included 136 eyes with penetrating eye injury, who were treated at the Trauma department of National Institute of Ophthalmology, Hanoi \ufffd?Vietnam from 1999-2000. Vitrectomy was performed through the limbal and pars plana in 135 patients, 105 boys and 30 girls. Results: Remove intraocular foreign body: 11%, procedure for retinal detachments: 14%. The common functional success (visual acuity of 5/2000 or better) rate was 55,1%. Functional success: absent retinal detachment: 60,7%; present: 21,1%. Anatomic success rate was 66,2%. 4 eyes (2,9%) were eviscerated. Complications of the surgery were: iridocyclite, edema of the cornea, hemorrhage, hyphema. Conclusion:Vitrectomy techniques showed its good effect in treating penetrating eye injury in children. Presence retinal damage and endophthalmitis have significant effect on the final visual outcomes.
Eye Injuries ; Penetrating/ surgery ; Vitrectomy ; Child ;

The acute toxicity (LD50) of herbal extract of HM2 was tested on white mice and the treatment effect of this herbal medication was investigated on 33 in-patients with chronic cerebral circulated hypofunction at Hµ T©y Hospital of Traditional Medicine. The results showed that HM2 was non-toxic in experimental animal at oral dose of 200g per kg. The adverse effect was not observed in clinical. This medication made no change in pulse, blood pressure, liver and renal function parameters as well as in hematological measurements. There was significant improvement in major symptoms.
Abnormalities ; Cerebral Arterial Diseases ; therapeutics

Background: Penetrating eye injury is common cause blind or many long-term complications later. One of the complications such as glaucoma in the eye. There were some research on glaucoma after penetrating eye injury, but no reports about the treatment of glaucoma. Objectives: To describe the clinical characteristics and assess the outcomes of surgery in the treatment of glaucoma after penetrating eye injury. Subjects and method: The author performed a prospective analysis of 32 eyes the underwent surgery causes by glaucoma after penetrating eye injury at Trauma department of National Institute of Ophthalmology. Follow up period: 6 months. Data was processed by using medical statistics methods on SPSS 10.5 software. Results: Of the 32 patients, 21 were men (65.6%) and 11 were women (34.4%). Localization of the injury: in the cornea 93.8%; lens damages 100%; vitreous organization 56.3%; retinal detachment 12.5%. Functional success (visual acuity >0.02): 18.8%, 4 eyes were enucleated. The normal intraocular pressure after surgery was 71.9%. Conclusion: The clinical characteristics of glaucoma after penetrating eye injury are complicated and multivariable. The rate of normal pressure after treatment was 71.9%.
Glaucoma/surgery ; Eye Injuries ; Penetrating ;

Background: Penetrating eye injury caused by mine explosion is a severe ophthalmologic injury. It is rare in Viet Nam and there were no studies on this type of injury. Objectives: To describe the clinical characteristics and evaluate the outcomes of surgery for penetrating eye injury caused by mine explosions. Subjects and method: The prospective analysis was conducted on 34 patients (36 eyes) with penetrating eye injury presented at the Trauma Department of Viet Nam National Institute of Ophthalmology. They were followed up for two years. Results: Out of the \r\n', u'34 patients, 31 were men (91.2%). Types of injury: corneal tear 93.8%, lens damage: 100%, vitreous damage: 56.3%, retinal detachment 25%, intraocular foreign body 72.2%. Initial visual acuity less than 0.02 was 96.9%. The final visual acuity was improved to better than 0.02 in 58.3% of patients. The intraocular pressures were normalized in 72.2% of patients after treatment. Conclusion: Penetrating eye injury caused by exploding mines has very severe clinical features. Despite of improvements in surgical techniques and instruments, the final visual acuity was still poor. The visual outcomes primarily depended on initial damages to the eye.\r\n', u'
Mine ; Penetrating eye injury ; Vitrectomy

Background: Alkali burns are severe injuries of the eyes. Recently, using topical steroid in treatment of ocular alkali burns has provided better outcomes. However, there is no study on treating ocular alkali burns by topical steroid in Vietnam. Objective: To describe the clinical characteristics and assess the outcome with topical steroid used in the treatment of ocular Alkali burns. Subject and Method: The author performed a prospective analysis of 45 alkali eye burns at the Trauma department of the National Institute of Ophalmology, Hanoi. All patients were treated with topical steroid and vitamin C. Results: There were 19 eyes were mild injures, 26 eyes were severe injuries. 32.5% had a good visual acuity. None of patients with severe injuries had a good visual acuity. Complications: corneal opacity: 42.2%, elevated IOP 17.8%. Conclusion: Treatment of ocular alkali burns with topical steroid and vitamin C is not associated with corneal perforating and provide a good outcome.
Alkali burn ; Steroid

Background: The post-traumatic glaucoma is a major cause inducing blindness of traumatic eyes. Recent, researches have shown that 5 fluoruoracil (5 FU) combined with surgery, which have a better result in treatment of general glaucoma and post-traumatic glaucoma. Objectives: To describe the clinical characteristics of post - traumatic glaucoma and assess the results of trabeculectomy with intra-operative application of 5 FU. Subject and methods: A descriptive, prospective analysis was taken on 32 patients, who had trabeculectomy with intra-operative application of 5 FU from August 2005 to December 2007 in the Traumatic Department of National Institute of Ophthalmology. Results: Post-traumatic glaucoma was seen mainly in young adults 71.9%; anterior angle recession combined lesions accounted for 25%; cataract 62.5%; fluid in anterior chamber 25%; anterior haemorrhage 37.5%. The intraocular pressure (lOP) was successfully controlled at least up to the following six months in 93.8% and the visual acuity was 0.02 and better in 62.5%. Conclusions: Trabeculectomy with antimetabolite therapy is an effective procedure in reducing IOP in post - traumatic glaucoma.
5 Fluorouracil ; post-traumatic glaucoma

30 patients with anemia due to bone marrow depression and 60 healthy people (control) ages of 17-50 were monitored the rate of MetHb, number of erythrocyte and amount of Hb. The results have showns that percentage of MetHb in the control was the same as other studies. The average number of erythrocyte in patients with anemia was 1,85 +/- 0,5 million/lit, significant lower than this of control. The percentage of MetHb in patients with anemia due to the bone marrow depression much higher than normal level. The disease occurred mainly in young men and its progress also was more servere.
Anemia ; Bone marrow ; Methemoglobin