A clinical trial was performed to evaluate the tocolytic possibility of nifedipin and to propose a treatment regimen for preterm labor in the National Hospital of Gynecol-Obstet from July 2003 to December 2003. There were 40 cases of preterm labor with gestational age 31 weeks and 3 uterine contractions per minute on average. Patients received a 10 mg sublingual loading dose every 20 minutes (maximum dose 40mg), and followed by 20 mg oral dose every 6- 8 hours. Result: the effectiveness in tocolysis of nifedipin is very fast. It took 60-80 minutes to arrest uterine contraction (70- 80%) (including contractions of high frequency and intensity), especially in urgent tocolysis. The lower the frequency and intensity is, the higher and sooner the effectiveness is. 92.5% of delivery were delayed for 48 hours. 82.85% were postponed until 36 weeks, and the mean time of prolonged pregnacy was 39 days. Side-effects were mild and transient and in normotensive pregnant women blood pressure was almost unaffected. This treatment regimen of nifedipin showed the effectiveness in preterm labor. In brief, nifedipin is an effective, safe, convenient and economic tocolytic agent. It may well represent the best suitable tocolytic alternative currently available and can be used widely in Viet Nam.
Obstetric Labor, Premature, Nifedipine, Tocolysis

After 5 years, since 1993, the strategies for polio eradication have been well implemented. Coverage of routine immunization with 3 doses of OPV to children under 1 year of age has always been maintained higher than 90%. Coverage of supplementary immunization with 2 doses of OPV to children under 5 years of age during the NIDs has been achieved greater than 98%, surveillance of all the acute flaccid paralysis cases with collection of 2 adequate stool specimens for the identification of wild poliovirus. The results of the surveillance show that wild poliovirus cases have disappeared, decreasing from 152 cases in 1993 to 0 cases in 1998. The last cases of wild poliovirus identified in Phu Yen province of Central region had the date of onset on the 29th January 1997.
Poliomyelitis ; Child ; Poliovirus

The results of the basic immunization of 3 doses of oral poliomyelitis vaccines for infant and boost immunization of 2 doses of oral poliomyelitis vaccine during 1993-1997 have shown that the poliomyelitis was significant reduced from 152 cases in 1993 to no case in 1998. The last case of poliomyelitis occurred in Phu yen province in 19th January 1997. In 2000, the poliomyelitis was eradicated in Vietnam. However, in order to prevent from returning the disease
Poliomyelitis ; Achievement

In the flowers of Sambicus nigra, flavonoids, amino acids and sugars were determined. Among them the main components were flavonoids, which accounted for 7,19±0,10%. From total flavonoid extracts, ,2 compounds were isolated by column chromatography and identified by UV,MS,and NMR spectroscope as quercetin-3-α rhamnopyranosyl- β -glucopyranose and quercetin
Chemistry ; Flowers ; Flavonoids ; Amino Acids ; Carbohydrates

Experimentally, hepatoprotective effect of DinhLang was expressed in mice. The extract of Dinh Lang leaf suppressed the increase of MDA level in brain and in liver of mice suffered from CCl4- induced hepatitis with antioxydant activity stronger than that of mixed extract and extract prepared from the root. Dinh Lang had manifested liver protective effect in tetrachlorurcarbone –induced acute hepatitis. Antioxydant effect expressed in the inhibition against the processes of peroxydation of cell membrane can be one of the mechanism of liver protective effect of Dinh Lang
Antioxidants ; Araliaceae ; liver

The primary school-based helminthiasis control project was carried out in 767 communes (39 districts of 11 provinces). It is a combinate of IEC activities and periodical deworming every 6 months with mebendazole 500mg. 1,217,754 school children times (in 1,146 primary schools) have been drug administrated, coverage 97.2% - 100%. Side effects were not high 0.03% - 0.29%. Stool examinations have shown that the prevalence of infection is 98.4% - 78.8% and 19.2% respectively in the North, Center and the South. The intensity of Ascaris, Trichuris and hookworm infection in almost of schools is not rather high. The KAP surveys have shown that the majority of school children and their parents have knowledges of the reasons and the complications of helminthiasis 62.3% - 80.5% and 99.0%. However, percentage of people using nightsoil as fertilizer is 10.3%
Helminthiasis ; World Health Organization ; Schools

The study was carried out on 35 subjects diagnosed definitely as Basedow by clinical symptoms and T3, T4, TSH reactions. The controlled group composes of 15 healthy persons. Results showed that the rate of females is more than males. Some functional indicators of the left ventricle, Co, EF% were higher than those of control, the volume of systolic blow decreased (p<0.05) due to the intoxication by thyroid hormone level and the volume of left ventrical and the negative correlation between the duration of disease and the blood expelling power of the left ventricle
Graves Disease ; Heart ; patients ; heart ; Ultrasonography ; anatomy & histology

The study included 112 patients with diagnosis of DMD at National Institute of Pediatrics and 24 patient’s brothers. The results showed that: value of definitive diagnosis of creatine kinase (CK) test were 100% (CK levels of 100% patients were higher than CK levels of normal children). CK method could detect very early DMD even patients who were not yet clinical expression (11/24 patient’s were not yet clinical expression detected DMD by CK). The value of CK for heterozygote detection was 82.3% for DMD patient’s mothers who had clearly family history and 35.3% for DMD patient’s mothers who had only one child with DMD in the family. Based on PCR result analysis, gene mutation of two DMD patient with clearly family history had not belonged to 48- exon.
diagnosis ; Creatine Kinase ; Heterozygote ; Muscular Dystrophy, Duchenne

The study of 122 children were rickets from 1 - 6 month old at Hai Phong Children Hospital from 2002 to 2003. The results: the most of mothers were in shortage of knowledge in rickets. There were many risk factors: mothers keeping their child from sunlight after birth, mothers on diet for the first 3 months, solid food complement before 4 months. Frequent signs of rickets were crying all the time, perspiration, alopecia. Hypocalcemia was found in 80.33%
Rickets ; Child ; Epidemiology

74 type 2 diabetes patients in Thai Nguyen were studied, there is an incidence of 70,2% of opthalmic complication, among them retine damage accounts for 47,3%. Cardiovasculary complications account for 72,2%, myocardiac ischema accounts for 67, renal complications compose of kidney failure of I stage to IIIa stage. There is a high rate of 39,2% of infection complications. There is a correlation between the increase of blood insuline and the complications. Elevated level of triglycerde predicts ophthalmic complications and cardiovasculary complication HLD-C decrease predicts kidney complications
Disease ; Diabetes Mellitus, Type 2 ; Cardiology