1.Surveillance of the relationship between arteriosclerosis condition and the changes of some coagulation factors
Journal of Vietnamese Medicine 2003;280(1):46-55
Studying retrospectively 117 cases of atherosclerosis in the Hospital of Hematology and Blood Transfusion in Ho Chi Minh city showed that: atherosclerosis is very common in elderly and the form of calcified plaque accounts for highest rate. Atherosclerosis is usually associated with other pathological status such as CHA, blood lipid disorder, diabetes and obesity
Blood Coagulation Factors
;
Arteriosclerosis
;
Blood
2.Studies on Antioxidant Activity of Polyscias fruticosa Harms. (Araliaceae)
Journal of Medicinal Materials - Hanoi 2003;8(5):142-146
Extracts from roots and leaves of Polyscias fruticosa Harms. (Araliaceae) and their combination have been studied on lipid peroxidation in mouse brain using an auto-oxidation and a free radical generating system: the Fenton’s reagent (ferrous iron + hydrogen peroxide). All the root, leaf and combined extracts have inhibitory action on peroxidation of lipids and trolox, a water-soluble analogue of vitamin E used as a reference antioxidant compound. The results also indicate that the leaf extract is the strongest of all.
Biochemistry
;
Plants
;
Plants, Medicinal
;
Araliaceae
3.Study on Japanese encephalitis immunization and control policy in Viet nam
Journal of Preventive Medicine 2005;15(2):71-74
National Institute of Hygiene and Epidemiology combined with International Vaccine
Institute to conduct a qualitative study on Japanese encephalitis immunization and control policy in Viet Nam in 2002. The study applied quick assess method including collection information from many source and interview. In 2 months, the study determined experienced lesson of Vietnam in giving Japanese encephalitis vaccine into open immunization program. The study showed that policy of Japanese encephalitis immunization in Vietnam was effect due to suitable strategies and correct decisions.
Encephalitis, Japanese
;
Immunization
4.Study on the tocolysis effectiveness of nifedipin on uterine contraction in the management of preterm labor
Journal of Medical Research 2005;36(3):44-52
A clinical trial was performed to evaluate the tocolytic possibility of nifedipin and to propose a treatment regimen for preterm labor in the National Hospital of Gynecol-Obstet from July 2003 to December 2003. There were 40 cases of preterm labor with gestational age 31 weeks and 3 uterine contractions per minute on average. Patients received a 10 mg sublingual loading dose every 20 minutes (maximum dose 40mg), and followed by 20 mg oral dose every 6- 8 hours. Result: the effectiveness in tocolysis of nifedipin is very fast. It took 60-80 minutes to arrest uterine contraction (70- 80%) (including contractions of high frequency and intensity), especially in urgent tocolysis. The lower the frequency and intensity is, the higher and sooner the effectiveness is. 92.5% of delivery were delayed for 48 hours. 82.85% were postponed until 36 weeks, and the mean time of prolonged pregnacy was 39 days. Side-effects were mild and transient and in normotensive pregnant women blood pressure was almost unaffected. This treatment regimen of nifedipin showed the effectiveness in preterm labor. In brief, nifedipin is an effective, safe, convenient and economic tocolytic agent. It may well represent the best suitable tocolytic alternative currently available and can be used widely in Viet Nam.
Obstetric Labor, Premature, Nifedipine, Tocolysis
5.Study on chemical composition of Sambucus nigra ssp. canadensis
Journal of Medicinal Materials - Hanoi 2004;9(2):39-42
In the flowers of Sambicus nigra, flavonoids, amino acids and sugars were determined. Among them the main components were flavonoids, which accounted for 7,19±0,10%. From total flavonoid extracts, ,2 compounds were isolated by column chromatography and identified by UV,MS,and NMR spectroscope as quercetin-3-α rhamnopyranosyl- β -glucopyranose and quercetin
Chemistry
;
Flowers
;
Flavonoids
;
Amino Acids
;
Carbohydrates
6.Studies on hepatoprotective activity of Polyscias fruticosa based on antioxidant mechanism
Journal of Medicinal Materials - Hanoi 2004;9(3):85-89
Experimentally, hepatoprotective effect of DinhLang was expressed in mice. The extract of Dinh Lang leaf suppressed the increase of MDA level in brain and in liver of mice suffered from CCl4- induced hepatitis with antioxydant activity stronger than that of mixed extract and extract prepared from the root. Dinh Lang had manifested liver protective effect in tetrachlorurcarbone –induced acute hepatitis. Antioxydant effect expressed in the inhibition against the processes of peroxydation of cell membrane can be one of the mechanism of liver protective effect of Dinh Lang
Antioxidants
;
Araliaceae
;
liver
7.Mid - evaluation activities of the primary school-base helminthiasis control project supported by Who (in 2002 - 2003)
Journal of Malaria and parasite diseases Control 2003;0(1):82-88
The primary school-based helminthiasis control project was carried out in 767 communes (39 districts of 11 provinces). It is a combinate of IEC activities and periodical deworming every 6 months with mebendazole 500mg. 1,217,754 school children times (in 1,146 primary schools) have been drug administrated, coverage 97.2% - 100%. Side effects were not high 0.03% - 0.29%. Stool examinations have shown that the prevalence of infection is 98.4% - 78.8% and 19.2% respectively in the North, Center and the South. The intensity of Ascaris, Trichuris and hookworm infection in almost of schools is not rather high. The KAP surveys have shown that the majority of school children and their parents have knowledges of the reasons and the complications of helminthiasis 62.3% - 80.5% and 99.0%. However, percentage of people using nightsoil as fertilizer is 10.3%
Helminthiasis
;
World Health Organization
;
Schools
8.Some changes of morphology and function of the heart of Basedow disease patients observed in TM and 2D ultrasonic image
Journal of Practical Medicine 2003;442(2):62-63
The study was carried out on 35 subjects diagnosed definitely as Basedow by clinical symptoms and T3, T4, TSH reactions. The controlled group composes of 15 healthy persons. Results showed that the rate of females is more than males. Some functional indicators of the left ventricle, Co, EF% were higher than those of control, the volume of systolic blow decreased (p<0.05) due to the intoxication by thyroid hormone level and the volume of left ventrical and the negative correlation between the duration of disease and the blood expelling power of the left ventricle
Graves Disease
;
Heart
;
patients
;
heart
;
Ultrasonography
;
anatomy & histology
9.Value of creatine kinase in early diagnosis, detection of the heterozygote, primary research gene level of Duchenne muscular dystrophy in Vietnamese patients
Journal of Medical Research 2003;23(3):114-119
The study included 112 patients with diagnosis of DMD at National Institute of Pediatrics and 24 patient’s brothers. The results showed that: value of definitive diagnosis of creatine kinase (CK) test were 100% (CK levels of 100% patients were higher than CK levels of normal children). CK method could detect very early DMD even patients who were not yet clinical expression (11/24 patient’s were not yet clinical expression detected DMD by CK). The value of CK for heterozygote detection was 82.3% for DMD patient’s mothers who had clearly family history and 35.3% for DMD patient’s mothers who had only one child with DMD in the family. Based on PCR result analysis, gene mutation of two DMD patient with clearly family history had not belonged to 48- exon.
diagnosis
;
Creatine Kinase
;
Heterozygote
;
Muscular Dystrophy, Duchenne
10.Rickets in children from 1 - 6 month old at Hai Phong Children Hospital in two years (2002 - 2003)
Journal of Vietnamese Medicine 2004;304(11):40-47
The study of 122 children were rickets from 1 - 6 month old at Hai Phong Children Hospital from 2002 to 2003. The results: the most of mothers were in shortage of knowledge in rickets. There were many risk factors: mothers keeping their child from sunlight after birth, mothers on diet for the first 3 months, solid food complement before 4 months. Frequent signs of rickets were crying all the time, perspiration, alopecia. Hypocalcemia was found in 80.33%
Rickets
;
Child
;
Epidemiology