Immune thrombocytopenia is the most common diagnosis of isolated thrombocytopenia. The dilemma encountered by paediatricians is missing diagnosis of acute leukaemia in children with isolated thrombocytopenia. We demonstrated childhood ITP could be diagnosed using a four point clinical criteria without missing a diagnosis of acute leukaemia. Hence, bone marrow examination is not necessary in children with typical features compatible with ITP prior to steroid therapy. This can encourage paediatricians to choose steroid therapy, which is cheaper and non-blood product, as first line platelet elevating therapy in children with significant haemorrhage.
Thrombocytopenic

No abstract available.
Purpura, Thrombocytopenic, Idiopathic*

No abstract available.
Purpura, Thrombocytopenic, Idiopathic*

No abstract available.
Purpura, Thrombocytopenic, Idiopathic*

No abstract available.
Purpura, Thrombocytopenic* ; Rifampin*

From Aug-2000 to Aug-2003 at HCM City Blood Transfusion and Hematology hospital, 31 cases of endoscopic splenectomy were studied to evaluate the effect of this surgery to treat chronical immuno-thrombocytopenic purpurea once corticotherapy and immunosupressive therapy failed. Results showed that one year after splenectomy, 64,52 – 76,92%, and 2 years after, 50% of cases had had completely positive response. There was absolute failure in 38,7% of cases within 3 first months, but from the 4th month, there was no relapse case. A half number of patients with failed splenectomy had had quick response to corticotherapy more.The duration of treatment was short, endoscopic splenectomy was safe. There was no death. No case of blood transfusion was needed. There were no complications
Splenectomy ; Therapeutics ; Purpura, Thrombocytopenic

Background: Idiopathic or Immune Thrombocytopenic Pupura (ITP) is a common disease in Vietnamese children. This is a hemostatic disorder disease diagnosed by clinical symptoms combining with tests of platelet quantity in peripheral blood and other tests. Objectives: to study epidemiology, clinical, para-clinical characteristics and their relations in ITP disease. Subjects and methods: This was a prospective and retrospective study. The study included 579 pediatric patients from 3 months to 16 ages who were diagnosed and treated ITP disease in National Pediatric Hospital from 1/1/2003 to 12/31/2004. Results: Data were analyzed, including 191 infants from >3-<12 months (33.0%), 293 children from 1 - 10 ages (50.6%), 95 children >10-<16 ages (16.4%). The male/female ratio was highest in infants and decreased with age (P < 0.001). The disease occurred more in September, October and November with advantage factor being acute respiratory infection before 2 to 3 weeks. Subcutaneous hemorrhage ratio was highest with 557 cases (96.2%), intracranial hemorrhage happened in 7 cases (1.7%). There were differences among age groups about hemorrhage situation. Anemia level did not corresponding with the decrease of the platelet count. Conclusion: Characteristics of ITP depend on the number of platelet and age. \r\n', u'\r\n', u'\r\n', u'
Purpura ; Thrombocytopenic ; Idiopathic/ epidemiology

Production of platelet concentrates (PCs) have an important role in the replacement therapy for severe thrombocytopenic conditions. PCs can be prepared by centrifugal technique which have two main methods: platelet rich plasma and buffy coat. We studied on 40 blood units (volume 450 ml, anticoagulant: CPD-A1, triple bags-type) and evaluated the yield of platelet (PLT) separation red blood cell (RBC) and white blood cell (WBC) contamination from these methods. The result show that the yield of PLT separation from PRP method is significantly higher than those from BC (82.60+ 7.20x1010, yield: 56.75% vs 50.59 + 2.97 yield: 32.4%) The WBC and RBC’s contamination in PCs from two methods are higher than the standard of Council of Europe. By sum up, follow studies will be necessary for decreasing the WBC and RPC’s contamination in PCs, the PRP method may be evaluated as a high-yield method in PCs production
Blood Platelets ; Purpura, Thrombocytopenic

The authors present a study on the pathological features of 45 spleens which were splenectomised by immune thrombocytopenic purpura (TTP) from 1/1/1990 to 31/12/1997 at Viet Duc hospital, 43/45 were women, age from 12 to 50, in which 35/45 were under 30 ages. Weight and sexe of these spleens were observed. They are in normal size or rather enlarged, but their weight are hyperplasis, but no sclerosis and nomalignacy: neutrophils, eosinophils, macrophages and sometimes megakaryocytes may be found in the red
Purpura, Thrombocytopenic ; Pathology

No abstract available.
Purpura, Thrombotic Thrombocytopenic*