1.Fluoride and Functionalised β-tricalcium Phosphate (fTCP) Fluoride Toothpaste Affect the Primary Dentin Caries Surface: A Comparison by Estimation Statistics
Trieu Kim Ly ; Thoai Quoc Kieu ; Nam Cong-Nhat Huynh ; Lan Thi Quynh Ngo
Archives of Orofacial Sciences 2021;16(1):57-67
ABSTRACT
This study aims to compare the effect of fTCP-contained toothpaste in combination with 950 ppm
fluoride on primary dentin caries surface to ordinary 1100 ppm fluoride toothpaste by using estimation
statistics. Dental caries with deep lesion and dentin exposure from nine primary teeth were cut into two
equal parts and randomly divided into two groups in a before-after study. Each group was brushed with
one type of toothpaste two times per day for 28 days and rested in artificial saliva. SEM images of cavity
bottom surfaces and energy-dispersive X-ray spectrometry (EDX) were used to determine the percentage
of calcium (Ca), phosphorus (P), fluoride (F) and oxygen (O) at six continuous measured areas from
the surface of the cavity bottom into 45 µm depth before and after brushing. About 95% confidence
interval of the mean difference was calculated by performing bootstrap resampling with 5000 resamples
followed by comparison analysis. The percentage of Ca, P, F, O was shifted after treatment. There was
no difference between the two groups. The SEM images reflected a similar illustration of EDX data. The
combination of fTCP and 950 ppm fluoride in toothpaste showed equivalent effectiveness to the 1100
ppm fluoride toothpaste in primary dentin caries.
Fluorosis, Dental
;
Dental Caries