The study involved 44 patients (22 males, 18 females, aged from 33 to 94 years) with acute ischemia of extremities due to peripheral arterial embolism, who were undergoing surgery for removing clots at ViÖt - §øc Hospital from January 1998 to December 2001. Results: the common clinical signs included the lack of pulse, cold extremities; loss sense and movement were advanced signs. Rate of amputation was high. 5 cases were given preoperative anticoagulation. One had to be amputated. 2 cases were received conservative management with fasiotomy. 2 cases were fail to angioplasty because of necrosis. Maintaining postoperative anticoagulation improved the chance of full extremity repairing prevented from recurrence, especially when the embolism was resolved
Embolism ; Diagnosis ; Therapeutics

Background:Rheumatic heart disease is an acquired heart disease which often seen in the year of 90's. Nowaday, due to the development of health care system, population benefit much of knowledge to prevent this disease, the rate of prevenlence reduce significant. Objectives:This study aims to diagnose and prevent relapse in childen with rheumatic heart diseasewho treated in National Hospital for Pediatrict. Subjects and method:A retrospective study was conducted on 236 children with rheumatic heart diseaseor cardiac valve diseasewho admitted at Cardiology department of the National Hospital for Pediatrics from 1st January 2001 to December 31, 2005. Results:29.7% (70/236) were hospitalized for rheumatic valve disease. Among 166 hospitalized children due to continuous rheumatic heart disease, the result showed that: The types of carditis and arthritis were the most frequent and at least 22.9% (38/166) of children had definitive permanent valve lesions . 65.7% (44/76 responses) children received proper prevention. Some of them were not monitored at the center of prevention. The greater part of the rest had no knowledge of this disease. Conclusion:Rheumatic heart disease reduced but the prevalence of heart valve complication increased.\r\n", u'\r\n', u'
Rheumatic Heart Disease/ diagnosis ; therapy ; Infant

Background: Mitral valve diseases are the most frequent in the cardiac valvular acquired diseases. Valvuloplasty is a very good surgical treatment, also its techniques are difficult. Objective: (1) To describe features of valvular lesion and technique of valvuloplasty. (2) To evaluate the effects of these operations. Subject and Method: 95 cases of mitral valve reconstruction were studied and described retrospectively about pre- operative features, mitral valvuloplasty, and post-operative results. Results: Pre-operative cardiac failure >=2 nd level (NYHA) is 96.8%, with 100% of mitral valve insufficiency, 28.4% associated with valvular stenosis. Mean age of patient is 34.5 +/- 13.2. Each case must do an average 4/15 valvuloplasty techniques, the most frequent are: mitral valvular ring (67.4%), commissurotomy (57.9%), cordage section (45.3%)\u2026 Early post \u2013 operative result is very good: no mortality, mitral valvular function is improved significantly than pre-operative (p<0.001), no severe mitral stenosis or insufficiency. Long-term post operative control (3 months, 3 years, 5 years post \u2013 operation) present the stability of this valvuloplasty with high survival frequency (96.8% in 3 months, 96.2% in 3 years, 93.4% in 5 years), in the 78.5% ranges a good level, re-operation is only required in 3 cases with valvular replacement. Conclusions: Although the difficult technique of valvuloplasty \u2013 especially in rheumatic lesion, mitral valve reconstruction is a good and safe technique to treat the mitral valve diseases.
Alkali burn ; Steroid

Background: Flail chest is a severe condition of thoracic trauma, and it requires diagnosis and treatment as soon as possible. From year 2000, we developed an improved technique of open fixation in order to adapt the situations of Vietnam health settings. Objectives: To report preliminary results of application of improved open fixation technique in Viet Duc Hospital from 2001 to 2006. Subjects and method: This descriptive, prospective and retrospective study involved 19 patients with flail chest due to closed thoracic trauma or multiple traumas, treated by open fixation technique. The parameters included features of patients, characteristics of this technique and postoperative progression.Results: Of 19 patients, there were 16 males and 3 females, mean age: 47.8 years. All patients presented obvious signs of flail chest preoperatively, but only 9 cases were treated by open fixation technique and pleural drainage immediately. This technique canbe applied in all sugical settings with single local anaesthesia, and any kind of common surgical threads. The most suitable initial pulled weight is 2000 g. All cases of flail chest required pleural drainage. All patients had good outcomes with open fixation technique, no death. There were 3 patients with postoperative complications, all were severe multiple trauma patients. Conclusion: Improved open fixation technique applied in Viet Duc Hospital is simple, effective and safe, and can be widely used in all surgical settings.
Flail Chest ; Flank Pain/ therapy ;

Background: Chronic obstructive pulmonary disease (COPD) remains a major public health problem. It is the fourth leading cause of chronic morbidity and mortality in the United States, and is projected to rank fifth in 2020 in burden of disease caused worldwide. Objective: To research the epidemiology of COPD in the population of Bac Giang city and finding out the risk factors of COPD. Subjects and method: Cross-sectional survey of general population sample of 2,104 men and women with the age \ufffd?0 years in 30 wards of 11 communes of Bac Giang city. Data on respiratory symptoms, diseases, and risk factors were collected. Lung function tests were performed with Spiroanalyzer snoo, Japan. Results and conclusions: The incidence of COPD was 2.3%; in men 3.0% and in women 1.7%. The incidence of simple chronic bronchitis was 6.4%. People who smoked had higher rate of COPD than the others (OR = 2.8). The incidence of smoking in COPD was 55.9%. The three most important risk factors of COPD was the age \ufffd?0; smoking >15 pack/year and medical history of asthma.
Pulmonary Disease ; Chronic Obstructive/ epidemiology

Background: Gastric cancer is a common disease in the world. For treatment, gastrectomy is still considered as the first choice. However, recovering of postoperative gastrointestinal circulation remains a controversial issue. Objectives: To assess the early results of 2 methods as gastroduodenostomy (Billroth I type) and gastrojejunostomy (Billroth type II) in recovering of gastrointestinal circulation. Subjects and method: A descriptive, retrospective study was conducted on 98 patients (61 males, 37 females, mean aged 48.1\xb112.7), were confirmed diagnosed with gastric cancer, treated in Military Central Hospital N.108 from May, 2001 to December, 2005. Results: Tumor positions were seen in 1/3 lower and 1/3 middle of gastric organ (59.2% and 40.8%, respective). There was no significant difference for invasive level of tumor between 2 groups (P>0.05). 62.2% patients with invasive level of tumor in stage of T4 in both 2 groups. Generally, the lesion between 2 forms of ulcer and rough differed significantly. The patients with and without metastatic lymph nodes were 57 and 41 patients, respective. All of patients were conducted with lymph node dissection at the stage of DIII-DIV. The difference between 2 groups for surgical time was no statistic significant. Conclusion: Billroth type I method combined with lymph nodes dissection was a safe and feasible technique in treatment of gastric cancer.
Stomach Neoplasms/ surgery ; Gastrectomy ; Lymph Node Excision ;

Background: Human Heparansulphate interacting protein (hHip) has been shown to participate in biological processes of cells. Several studies indicated that hHip transcript is up regulated in several of cancer tissues including those of thyroid, colon, breast and prostate. Antibody against hHIP is necessary for methods to evaluate protein level of HIP in cancer tissues. Objectives:The aims of study was to induce anti hHIP antibody in rabbit and purify and conserve purified anti hHIP antibody. Subjects and method: The study included 9 adult and healthy rabbits with the weight 2 - 2.5kg. Immunization hHIP peptide-KLH in rabbit. Purify anti hHIP antibody using affinity chromatography. Results: The results shown synthesize hHIP peptide and conjugate it with carrier protein. Sensitive rabbit better meet with hHIP-KLH antibody. The Ig concentration obtained in sensitive rabbit was rather high and equal. Immunization hHIP-KLH successfully in rabbit. Obtainment valuable amount of anti hHIP antibody. Conclusion: Successfully induce and purify anti hHIP antibody from rabbit. Establish a standard protocol for polyclonal antibody against small peptide in rabbit.\r\n', u'\r\n', u'
Carrier Proteins/ administration & ; dosage ; chemistry ; Rabbits

Background: Phu Cat district, Binh Dinh province is one of the areas contaminated with Agent Orange in Wartime and now up to it still continues to affect the environmental life and health of people living there. Objectives: Investigate the factual status of mortality rate from 2002 to 2006 in Phu Cat district, Binh Dinh province and determine the burden of mortality based on the number of Years of Lost Life (YLLs). Subject and methods: A retrospective study was conducted on all deaths from January 1, 2002 to December 31, 2006 in Phu Cat population. Burden of mortality was analyzed using the WHO standard method. The dead cases were causal diagnosed by Verbal Autopsy tools and update information for mortality rate. Results: Mortality rates were 3.1%o (2002), 3.3%o (2003), 4.08%o (2004) and 2.67% (2005). YLLs from 2002 to 2006 in order are: 55.87%, 57.98%, 73.82%, 48.74% and 49.01%, respectively. The number of mortality in men was higher than women and had a tendency to increase from 2002 to 2004, to decrease during 2005 and 2006. YLLs in group of ages 0-4 was highest in 2004 (150.76%o), followed by 2002 (126.28%o) and was lowest in 2005 (39.72%o). YLLs in groups of ages >60 was high, especially in non-communicable disease. Conclusions: Mortality model from 2002 to 2006 in Phu Cat district, Binh Dinh province was appropriate for the national mortality model. According to YLLs, the burden of mortality was determined as the general burden of mortality from 2002 to 2006 and burden of mortality followed disease groups: communicable disease, nutrition disease and pregnancy; non-communicable disease; poisoned and accident related diseases.
burden of mortality ; mortality

Background: Video-assisted thoracoscopic surgery (VATS) is a now new, effective approach in diagnosis and treatment of thoracic diseases. Objective: To summarize and evaluate the results of VATS for mediastinal tumors. Subjects and method: A retrospective study included patients with mediastinal tumors who performed VATS in Viet Duc Hospital from March 2006 to August 2007. The measurements about age, sex, hospital-admitted reasons, tumor\u2019s size and location, outcomes and complications were analysed. Results: There were sixteen patients, included 9 males and 7 females. The patients\ufffd?average age was 35.3 years (ranged from 16 to 72 years). Clinical characteristics of mediastinal tumors were chest pain (11 cases), trouble breathing (4 cases), cough (2 cases). CT scanner detected mediastinal tumors in all patients (16 cases). Pathologically, 15 patients had benign tumors and only one had malignant tumor. The average time for postoperative drainage withdrawal was 3.0625 days (ranged from 2 to 5 days). The average time of hospital stay was 5 days (ranged from 3 to 11 days). There was no postoperative complication. Conclusion: VATS for mediastinal tumors obtained good outcomes. This was a selective method with many advantages for mediastinal tumors.
Mediastinal Neoplasms/surgery ; Thoracic Surgery ; Video-Assisted ;

Background: In 2006, the project of global fund for malaria prevention in Vietnam provided a large number of rapid diagnostic test Paracheck F for Vietnam for the purpose of rapid malaria diagnose. However, there is no study on evaluation the effect of rapid diagnostic test compared with microscopy method. Objective: To evaluate the diagnostic yield and cost of paracheck F test and microscopy in malaria diagnosis and treatment. Subject and Method: The study was carried out in 6 communes belongs to Quang Tri and Quang Binh provinces from September to November - 2006. The study was divided into 3 phases. Phase 1: diagnoses and treatments are based on clinical symptoms, phase 2: diagnoses and treatments are based on the results of paracheck and phase 3: diagnoses and treatments are based on the results of microscopy. All phases, both the common patients and malarial patients and the amount of anti-malarial drugs were treated, the amount of money was spent on transport and days work off of malarial patients and their relatives were calculated. Result: The investigation data on expenditure of malaria patients showed that: the average direct cost of malaria patient in phase 1 is VND 116.100; phase 2: VND 119.400 and phase 3: VND 120.800 per 1 treatment course. There is no significant difference between direct costs in three phases (p > 0.05). Conclusion: The expense efficiency for finding out a case of malaria by paracheck and microscopy is equivalent and lower than the expense of diagnosis based on clinical symptoms.
Malaria diagnosis ; RDT Paracheck F ; microscopy